Explanipedia

Remote interviews for medical residency selection during the initial COVID-19 crisis: a national survey Open

Mohamad‐Hani Temsah, Fadiah Alkhattabi, Fadi Aljamaan, Khalid Alhasan, Adi Alherbish , et al. · 2021

Remote Interviews for Medical Residency Selection During the Initial COVID-19 Crisis: a National Survey Open

Mohamad‐Hani Temsah, Fadiah Alkhattabi, Khalid Alhasan, Adi Alherbish, Mona F. Philby , et al. · 2021

Background: During the coronavirus disease 2019 (COVID-19) pandemic, structured medical training is challenging because the necessary travel for on-site interviews could increase the spread of the disease.Aim: This study was conducted to d…

Altered Regional Brain Cortical Thickness in Pediatric Obstructive Sleep Apnea Open

Paul M. Macey, David Gozal, J. Prasad, A. Richard, Rajesh Kumar , et al. · 2018

Changes in cortical thickness are present in children with OSA and likely indicate disruption to neural developmental processes, including maturational patterns of cortical volume increases and synaptic pruning. Regions with thicker cortic…

Nocturnal Oximetry–based Evaluation of Habitually Snoring Children Open

Roberto Hornero, David Gozal, Gonzalo C. Gutiérrez‐Tobal, Mona F. Philby, María Luz Alonso-Álvarez , et al. · 2017

Neural network-based automated analyses of nSp_O₂ recordings provide accurate identification of OSA severity among habitually snoring children with a high pretest probability of OSA. Thus, nocturnal oximetry may enable…

Angiopoietin‐2 and soluble Tie‐2 receptor plasma levels in children with obstructive sleep apnea and obesity Open

David Gozal, Abdelnaby Khalyfa, Zhuanghong Qiao, Dale L. Smith, Mona F. Philby , et al. · 2017

Objective Obstructive sleep apnea (OSA) is a prevalent condition, especially in children with obesity, and is associated with increased risk for metabolic syndrome (MetS). Angiopoietins have been identified as potential biomarkers of endot…

Reduced Regional Grey Matter Volumes in Pediatric Obstructive Sleep Apnea Open

Mona F. Philby, Paul M. Macey, A. Richard, Rajesh Kumar, David Gozal , et al. · 2017

EFECTO DE LA GRAVEDAD DEL TRASTORNO RESPIRATORIO DEL SUEÑO SOBRE EL DESEMPEÑO COGNITIVO EN UNA COHORTE DE NIÑOS EN EDAD ESCOLAR Open

Stephanie A Hunter, David Gozal, David Smith, Mona F. Philby, J Kaylegian , et al. · 2017

Comentario de experto 80Tal como ya se ha mencionado, los trastornos respiratorios del sueño (TRS)se asocian con una alto riesgo de desarrollar alteraciones cognitivas en los niños.Sin embargo no está claro si la asociación es dependiente …

Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Elevated Lipoprotein‐Associated Phospholipase A2 Plasma Activity Levels Open

David Gozal, Mona F. Philby, Zhuanghong Qiao, Abdelnaby Khalyfa, David Gozal · 2017

Background Obstructive sleep apnea ( OSA ) is a highly prevalent condition, especially in obese children, and has been associated with increased risk for endothelial dysfunction and dislipidemia, which are precursors of atherosclerosis. Li…

<i>ERJ</i>Podcast December 2016: Assessing the worldwide epidemiology of sarcoidosis Open

Martin R. Miller, Mina Gaga, Εleftherios Ζervas, Marc Humbert, Yvette C. Cozier , et al. · 2016

Impact of sleep disordered breathing on behaviour among elementary school-aged children: a cross-sectional analysis of a large community-based sample Open

Dale L. Smith, David Gozal, Scott J. Hunter, Mona F. Philby, Jaeson Kaylegian , et al. · 2016

Sleep disordered breathing (SDB) in children has been associated with inattention, impulsivity and hyperactivity, but the associations between SDB severity and the type and severity of behavioural disruption are unclear. 1022 children aged…

Biomarkers of Alzheimer Disease in Children with Obstructive Sleep Apnea: Effect of Adenotonsillectomy Open

David Gozal, Mona F. Philby, María Luz Alonso-Álvarez, Joaquín Téran‐Santos, David Gozal · 2016

Thus, OSA, and particularly OSA+OB, are associated with increased plasma levels of AD biomarkers, which decline upon treatment of OSA in a representative, yet not all- encompassing subset of patients, suggesting that OSA may accelerate AD-…

Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea Open

Abdelnaby Khalyfa, David Gozal, Ahamed Khalyfa, Mona F. Philby, María Luz Alonso-Álvarez , et al. · 2016

These observations elucidate a novel role of exosomal miRNA-360 as a putative key mediator of vascular function and cardiovascular disease risk in children with underlying OSA and/or obesity, and identify therapeutic targets.

Table of Contents Open

Shahid Farhan, Eduard Shantsila, Gregory Y.H. Lip, Richard Allman, Apostolos Perelas , et al. · 2016

Effect of Sleep-disordered Breathing Severity on Cognitive Performance Measures in a Large Community Cohort of Young School-aged Children Open

Scott J. Hunter, David Gozal, Dale L. Smith, Mona F. Philby, Jaeson Kaylegian , et al. · 2016

This large community-based sample of children highlights the significant deleterious impact of SDB, particularly in children with moderate to severe obstructive sleep apnea, and also that even snoring alone affects neurocognitive function.…

Impact of obstructive sleep apnoea on insulin resistance in nonobese and obese children Open

Dorit Koren, David Gozal, Mona F. Philby, Rakesh Bhattacharjee, David Gozal · 2016

Obstructive sleep apnoea (OSA) has been inconsistently associated with insulin resistance and adverse metabolic states. We aimed to assess independent contributions of OSA to insulin resistance and dyslipidaemia in a large paediatric cohor…

Impact of Adenotonsillectomy on Insulin Resistance and Lipoprotein Profile in Nonobese and Obese Children Open

Dorit Koren, David Gozal, Rakesh Bhattacharjee, Mona F. Philby, David Gozal · 2015

Automated analysis of nocturnal oximetry as screening tool for childhood obstructive sleep apnea-hypopnea syndrome Open

Daniel Álvarez, David Gozal, Gonzalo C. Gutiérrez‐Tobal, Andrea Crespo, Mona F. Philby , et al. · 2015

Childhood obstructive sleep apnea-hypopnea syndrome (OSAHS) is a highly prevalent condition that negatively affects health, performance and quality of life of infants and young children. Early detection and treatment improves neuropsycholo…

Analysis and classification of oximetry recordings to predict obstructive sleep apnea severity in children Open

Gonzalo C. Gutiérrez‐Tobal, David Gozal, Daniel Álvarez, Andrea Crespo, Mona F. Philby , et al. · 2015

Current study is focused around the potential use of oximetry to determine the obstructive sleep apnea-hypopnea syndrome (OSAHS) severity in children. Single-channel SpO2 recordings from 176 children were divided into three severity groups…

Pupillometric findings in children with obstructive sleep apnea Open

Mona F. Philby, Seçil Aydınöz, David Gozal, Selim Kılıç, Rakesh Bhattacharjee , et al. · 2015

Insights into Selected Aspects of Pediatric Sleep Medicine Open

Alex Gileles‐Hillel, Mona F. Philby, Gabrielle Lapping‐Carr · 2015

Quality of Life and Obstructive Sleep Apnea Symptoms

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