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View article: Characterizing the consistency of motion of spermatozoa through nanoscale motion tracing
Characterizing the consistency of motion of spermatozoa through nanoscale motion tracing Open
Kinematic features derived from nanoscale motion traces of spermatozoa contain information complementary to the speed of the sperms, allowing further distinction among the progressively motile sperms. Some highly progressive spermatozoa ma…
View article: Super-resolution histology of paraffin-embedded samples via photonic chip-based microscopy
Super-resolution histology of paraffin-embedded samples via photonic chip-based microscopy Open
Fluorescence-based super-resolution optical microscopy (SRM) techniques allow the visualization of biological structures beyond the diffraction limit of conventional microscopes. Despite its successful adoption in cell biology, the integra…
View article: Chitosan-based delivery system enhances antimicrobial activity of chlorhexidine
Chitosan-based delivery system enhances antimicrobial activity of chlorhexidine Open
Infected chronic skin wounds and other skin infections are increasingly putting pressure on the health care providers and patients. The pressure is especially concerning due to the rise of antimicrobial resistance and biofilm-producing bac…
View article: Biallelic <i>ANGPT2</i> loss-of-function causes severe early-onset non-immune hydrops fetalis
Biallelic <i>ANGPT2</i> loss-of-function causes severe early-onset non-immune hydrops fetalis Open
Background Hydrops fetalis, a pathological fluid accumulation in two or more body compartments, is aetiologically heterogeneous. We investigated a consanguineous family with recurrent pregnancy loss due to severe early-onset non-immune hyd…
View article: Photonic chip-based multimodal super-resolution microscopy for histopathological assessment of cryopreserved tissue sections
Photonic chip-based multimodal super-resolution microscopy for histopathological assessment of cryopreserved tissue sections Open
Histopathological assessment involves the identification of anatomical variations in tissues that are associated with diseases. While diffraction-limited optical microscopes assist in the diagnosis of a wide variety of pathologies, their r…
View article: Photonic chip-based multimodal super-resolution microscopy for histopathological assessment of cryopreserved tissue sections
Photonic chip-based multimodal super-resolution microscopy for histopathological assessment of cryopreserved tissue sections Open
1. Abstract Histopathological assessment involves the identification of anatomical variations in tissues that are associated with diseases. While diffraction-limited optical microscopes assist in the diagnosis of a wide variety of patholog…
View article: Photonic-chip: a multimodal imaging tool for histopathology
Photonic-chip: a multimodal imaging tool for histopathology Open
We propose the photonic-chip as a multimodal imaging platform for histopathological assessment, allowing large fields-of-view across diverse microscopy methods including total internal reflection fluorescence and single-molecule localizati…
View article: High throughput spatially sensitive single-shot quantitative phase microscopy
High throughput spatially sensitive single-shot quantitative phase microscopy Open
High space-bandwidth product with high spatial phase sensitivity is indispensable for a single-shot quantitative phase microscopy (QPM) system. It opens avenue for widespread applications of QPM in the field of biomedical imaging. Temporal…
View article: Replication data for: Following the Fate of Dye-Containing Liposomes in Vitro
Replication data for: Following the Fate of Dye-Containing Liposomes in Vitro Open
This dataset contains the experimental work associated to the publication "Following the Fate of Dye-Containing Liposomes In Vitro" Int. J. Mol. Sci. 2020, 21(14), 4847; https://doi.org/10.3390/ijms21144847. The rather limited success of …
View article: Following the Fate of Dye-Containing Liposomes In Vitro
Following the Fate of Dye-Containing Liposomes In Vitro Open
The rather limited success of translation from basic research to clinical application has been highlighted as a major issue in the nanomedicine field. To identify the factors influencing the applicability of nanosystems as drug carriers an…
View article: Visualizing ultrastructural details of placental tissue with super-resolution structured illumination microscopy
Visualizing ultrastructural details of placental tissue with super-resolution structured illumination microscopy Open
Super-resolution fluorescence microscopy is a widely employed technique in cell biology research, yet remains relatively unexplored in the field of histo-pathology. Here, we describe the sample preparation steps and acquisition parameters …
View article: Role of Laeverin in the pathophysiology of preeclampsia
Role of Laeverin in the pathophysiology of preeclampsia Open
Preeclampsia is a pregnancy-specific disease, affecting 5-10% of human pregnancies worldwide. It is defined as new-onset hypertension after 20 weeks of gestation with either proteinuria and/or organ failure. Laeverin is a membrane-bound am…
View article: Maternal serum laeverin (aminopeptidase Q) measured in the first trimester of pregnancy does not predict preeclampsia
Maternal serum laeverin (aminopeptidase Q) measured in the first trimester of pregnancy does not predict preeclampsia Open
Objective: The aim of this study was to compare the laeverin level in maternal serum from first trimester (11-14 weeks) of pregnancy between normal pregnancies and pregnancies that later developed preeclampsia (PE). Material and methods: T…
View article: Laeverin protein expression in normal and preeclamptic placentas using tissue microarray analysis
Laeverin protein expression in normal and preeclamptic placentas using tissue microarray analysis Open
Introduction Laeverin is a placenta‐specific protein that is normally expressed in the plasma membrane of human trophoblasts. In previous studies, we showed higher expression levels of laeverin gene in preeclamptic compared with normal pla…
View article: Longitudinal reference ranges for maternal plasma laeverin, and its role as a potential biomarker of preeclampsia
Longitudinal reference ranges for maternal plasma laeverin, and its role as a potential biomarker of preeclampsia Open
Maternal plasma levels of laeverin decrease with advancing gestation during the second half of normal pregnancy and lower levels measured at 22-24 weeks might be associated with the development of preeclampsia later in gestation.
View article: Differentially Expressed MicroRNAs in Meningiomas Grades I and II Suggest Shared Biomarkers with Malignant Tumors
Differentially Expressed MicroRNAs in Meningiomas Grades I and II Suggest Shared Biomarkers with Malignant Tumors Open
Meningiomas represent the most common primary tumors of the central nervous system, but few microRNA (miRNA) profiling studies have been reported so far. Deep sequencing of small RNA libraries generated from two human meningioma biopsies W…