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View article: Gut mycobiome and neuropsychiatric disorders: insights and therapeutic potential
Gut mycobiome and neuropsychiatric disorders: insights and therapeutic potential Open
Background The human gut mycobiome, a minor but integral component of the gut microbiome, has emerged as a significant player in host homeostasis and disease development. While bacteria have traditionally been the focus of gut microbiome s…
View article: Keratoconus in children in Tunisia: Epidemiological, clinical and therapeutic features
Keratoconus in children in Tunisia: Epidemiological, clinical and therapeutic features Open
Aim: To report the clinical and therapeutic particularities of pediatric keratoconus (KC). Methods: Retrospective study focusing on patients aged less than 18 years, presenting with KC and followed in a tertiary reference center in Sfax, T…
View article: CSIG-05. IS THERE ANY BRAIN TUMOR PREDISPOSITION IN RELATED PALLISTER-HALL SYNDROMES AT THE NEW GENOMICS ERA
CSIG-05. IS THERE ANY BRAIN TUMOR PREDISPOSITION IN RELATED PALLISTER-HALL SYNDROMES AT THE NEW GENOMICS ERA Open
Pallister-Hall Syndrome (PHS) and its related syndromes are a spectrum of congenital malformations. They are associated to GLI3 mutations and specific brain tumors. Considered as lethal, it is now well established that this disease may be …
View article: The gut-eye axis: the retinal/ocular degenerative diseases and the emergent therapeutic strategies
The gut-eye axis: the retinal/ocular degenerative diseases and the emergent therapeutic strategies Open
The interplay between human microbiota and various physiological systems has garnered significant attention in recent years. The gut microbiota plays a critical role in maintaining physiological homeostasis and influences various aspects o…
View article: Evaluation of nerve fiber layer and ganglion cell complex changes in patients with migraine using optical coherence tomography
Evaluation of nerve fiber layer and ganglion cell complex changes in patients with migraine using optical coherence tomography Open
Our study emphasize the significant impact of both types of migraine on retinal structures. OCT would serve as a valuable biomarker in migraine.
View article: Preoperative anxiety and postoperative pain associated with cataract surgery under local anesthesia
Preoperative anxiety and postoperative pain associated with cataract surgery under local anesthesia Open
Introduction: Although cataract surgery is a routine outpatient surgery, anxiety and pain remain two significant concerns seen in patients. Purpose: To describe preoperative anxiety and postoperative pain related to cataract surgery under …
View article: A rare ocular manifestation of mycoplasma pneumoniae infection.
A rare ocular manifestation of mycoplasma pneumoniae infection. Open
Management of atypical optic neuritis in a young adult requires consideration and serologic testing for Mycoplasma Pneumoniae especially in endemic regions.
View article: PCR Assay Using 22q11.2 Highly Polymorphic Markers for Exclusion of 22q Microdeletion: Technical Optimization and Application in North Africa
PCR Assay Using 22q11.2 Highly Polymorphic Markers for Exclusion of 22q Microdeletion: Technical Optimization and Application in North Africa Open
22q11.2 deletion syndrome is a genomic disorder with a broader clinical and genetic spectrum. To exclude the presence of 22q11.2 microdeletion, we optimize a PCR-RFLP analysis of three SNP located in the typically proximal 22q11.21 deleted…
View article: Advances in Genetic Polymorphisms
Advances in Genetic Polymorphisms Open
The field of single nucleotide polymorphisms (SNPs) analysis has undergone impressive advancement, mainly due to the advent of modern high-throughput genotyping technologies and the emergence of innovative algorithms and computational meth…
View article: Clinical and therapeutic characteristics of childhood uveitis in a tertiary center in Tunisia.
Clinical and therapeutic characteristics of childhood uveitis in a tertiary center in Tunisia. Open
Childhood uveitis is a serious pathology with frequent and vision-threatening complications. The etiologies are variable and the assessment can remain negative. A rigorous diagnostic approach, an oriented etiological assessment in collabor…