Monia Garofolo
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View article: Oral polychemotherapy to induce remission in newly diagnosed type 2 diabetes: a pragmatic, multicenter, randomized controlled trial
Oral polychemotherapy to induce remission in newly diagnosed type 2 diabetes: a pragmatic, multicenter, randomized controlled trial Open
Objective: to assess the incremental efficacy of a four-drug (POLYCHEM: metformin/pioglitazone/sitagliptin/empagliflozin) regimen vs standard diabetes care (SDC) in inducing remission in patients with newly diagnosed type 2 diabetes. Resea…
View article: Association of Albuminuria Within the Normoalbuminuric Range With All‐Cause Mortality in People With Type 2 Diabetes
Association of Albuminuria Within the Normoalbuminuric Range With All‐Cause Mortality in People With Type 2 Diabetes Open
Aims To investigate the independent association of albuminuria within the normoalbuminuric range with all‐cause mortality in normoalbuminuric people with type 2 diabetes with and without chronic kidney disease (CKD). Materials and Methods …
View article: Prognostic impact of switching to the 2021 chronic kidney disease epidemiology collaboration creatinine-based equation in Caucasian patients with type 2 diabetes: the Renal Insufficiency and Cardiovascular events (RIACE) Italian Multicenter Study
Prognostic impact of switching to the 2021 chronic kidney disease epidemiology collaboration creatinine-based equation in Caucasian patients with type 2 diabetes: the Renal Insufficiency and Cardiovascular events (RIACE) Italian Multicenter Study Open
ClinicalTrials.gov, NCT00715481, retrospectively registered 15 July, 2008.
View article: Relationship between degree of risk factor control and all-cause mortality in individuals with type 2 diabetes: A prospective cohort study
Relationship between degree of risk factor control and all-cause mortality in individuals with type 2 diabetes: A prospective cohort study Open
View article: Association between age at diagnosis and all-cause mortality in type 2 diabetes: the Renal Insufficiency and Cardiovascular Events (RIACE) Italian Multicenter Study
Association between age at diagnosis and all-cause mortality in type 2 diabetes: the Renal Insufficiency and Cardiovascular Events (RIACE) Italian Multicenter Study Open
Aims It is unclear whether type 2 diabetes diagnosed in young adulthood is associated with increased severity than that occurring later in life beyond longer lifetime exposure to hyperglycemia. This study aimed at assessing the independent…
View article: Fatty liver index is an independent risk factor for all-cause mortality and major cardiovascular events in type 1 diabetes: an 11-year observational study
Fatty liver index is an independent risk factor for all-cause mortality and major cardiovascular events in type 1 diabetes: an 11-year observational study Open
View article: Independent association of history of diabetic foot with all-cause mortality in patients with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study
Independent association of history of diabetic foot with all-cause mortality in patients with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study Open
View article: Independent association of estimated pulse-wave velocity with all-cause mortality in individuals with type 2 diabetes
Independent association of estimated pulse-wave velocity with all-cause mortality in individuals with type 2 diabetes Open
Background Estimated pulse-wave velocity (ePWV), a surrogate measure of arterial stiffness, was shown to independently predict morbidity and mortality from cardiovascular disease and other causes in both the general population and high-ris…
View article: Empagliflozin in adults hospitalised with COVID-19: a (null) hypothesis for RECOVERY
Empagliflozin in adults hospitalised with COVID-19: a (null) hypothesis for RECOVERY Open
View article: Short-term effectiveness of dapagliflozin versus DPP-4 inhibitors in elderly patients with type 2 diabetes: a multicentre retrospective study
Short-term effectiveness of dapagliflozin versus DPP-4 inhibitors in elderly patients with type 2 diabetes: a multicentre retrospective study Open
View article: Body mass index versus surrogate measures of central adiposity as independent predictors of mortality in type 2 diabetes
Body mass index versus surrogate measures of central adiposity as independent predictors of mortality in type 2 diabetes Open
View article: Type 2 diabetes albuminuric and non‐albuminuric phenotypes have different morphological and functional ultrasound features of diabetic kidney disease
Type 2 diabetes albuminuric and non‐albuminuric phenotypes have different morphological and functional ultrasound features of diabetic kidney disease Open
Aims Whether different diabetic kidney disease (DKD) phenotypes recognise differences in morphological and vascular properties of the kidney is still unexplored. We evaluated the potential role of kidney ultrasonography in differentiating …
View article: Risk of all-cause mortality according to the European Society of Cardiology risk categories in individuals with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study
Risk of all-cause mortality according to the European Society of Cardiology risk categories in individuals with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study Open
View article: Distribution according to the European Society of Cardiology risk categories and associated risk of all-cause mortality in individuals with type 2 diabetes: A prospective cohort study
Distribution according to the European Society of Cardiology risk categories and associated risk of all-cause mortality in individuals with type 2 diabetes: A prospective cohort study Open
Background. Atherosclerotic cardiovascular disease (ASCVD) is the main cause for the excess mortality in type 2 diabetes. In 2019, the European Society of Cardiology (ESC) identified three risk categories, with the very high-risk category …
View article: Insuline oltre l’insulina
Insuline oltre l’insulina Open
Insulin pumps, or systems for Continuous Subcutaneous Insulin In-fusion (CSII), have changed from rudimentary devices with limited dosing flexibility to “smart” systems able to modulate insulin administration with greater flexibility and a…
View article: <i>SIRT1</i> rs7896005 polymorphism affects major vascular outcomes, not all‐cause mortality, in Caucasians with type 2 diabetes: A 13‐year observational study
<i>SIRT1</i> rs7896005 polymorphism affects major vascular outcomes, not all‐cause mortality, in Caucasians with type 2 diabetes: A 13‐year observational study Open
Aims SIRT1 exerts effects on ageing and lifespan, as well cardiovascular (CV) disease risk. SIRT1 gene is very polymorph with a few tagging single nucleotide polymorphisms (SNPs) so far identified. Some SNPs, including rs7896005, were asso…
View article: Contents
Contents Open
View article: Glycaemic control during the lockdown for COVID-19 in adults with type 1 diabetes: A meta-analysis of observational studies
Glycaemic control during the lockdown for COVID-19 in adults with type 1 diabetes: A meta-analysis of observational studies Open
View article: All-cause mortality prediction models in type 2 diabetes: applicability in the early stage of disease
All-cause mortality prediction models in type 2 diabetes: applicability in the early stage of disease Open
View article: Response to Comment on Garofolo et al. Insulin Resistance and Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-up Study. Diabetes Care 2020;43:e139–e141
Response to Comment on Garofolo et al. Insulin Resistance and Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-up Study. Diabetes Care 2020;43:e139–e141 Open
Gonzalez-Clemente et al. (1) claim that a simpler though efficient assessment of cardiovascular risk in people with type 1 diabetes (T1D) is much needed. Since we showed that the estimated glucose disposal rate (eGDR) was an independent pr…
View article: Insulin Resistance and Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-up Study
Insulin Resistance and Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-up Study Open
In spite of being at target for glucose (1) or traditional cardiovascular (CV) risk factors (2), individuals with type 1 diabetes (T1D) still have an excess of CV mortality and morbidity implying a role for other mechanisms including insul…
View article: MON-661 Association of 25-Hydroxyvitamin D Serum Levels with Markers of Glycemic Control in Diabetic and Nondiabetic Patients on Maintenance Hemodialysis
MON-661 Association of 25-Hydroxyvitamin D Serum Levels with Markers of Glycemic Control in Diabetic and Nondiabetic Patients on Maintenance Hemodialysis Open
Introduction: In type 2 diabetic patients (T2DM) with end-stage renal disease (ESRD) on hemodialysis (HD), an inverse relationship between 25(OH)D and glycated hemoglobin (HbA1c) have been reported. However, because of anemia and altered r…
View article: The Synergic Association of hs-CRP and Serum Amyloid P Component in Predicting All-Cause Mortality in Patients With Type 2 Diabetes
The Synergic Association of hs-CRP and Serum Amyloid P Component in Predicting All-Cause Mortality in Patients With Type 2 Diabetes Open
OBJECTIVE Type 2 diabetes is characterized by increased death rate. In order to tackle this dramatic event, it becomes essential to discover novel biomarkers capable of identifying high-risk patients to be exposed to more aggressive preven…
View article: LA MALATTIA RENALE CRONICA NON-ALBUMINURICA NEL DIABETE MELLITO TIPO 1
LA MALATTIA RENALE CRONICA NON-ALBUMINURICA NEL DIABETE MELLITO TIPO 1 Open
View article: Microvascular complications burden (nephropathy, retinopathy and peripheral polyneuropathy) affects risk of major vascular events and all-cause mortality in type 1 diabetes: a 10-year follow-up study
Microvascular complications burden (nephropathy, retinopathy and peripheral polyneuropathy) affects risk of major vascular events and all-cause mortality in type 1 diabetes: a 10-year follow-up study Open
Background Microvascular complications (MC) have been claimed to increase the risk for cardiovascular disease in diabetic subjects. However, the effect of MC burden on the risk of major vascular outcomes and all-cause mortality in type 1 d…
View article: Estimation of Mortality Risk in Type 2 Diabetic Patients (ENFORCE): An Inexpensive and Parsimonious Prediction Model
Estimation of Mortality Risk in Type 2 Diabetic Patients (ENFORCE): An Inexpensive and Parsimonious Prediction Model Open
Context We previously developed and validated an inexpensive and parsimonious prediction model of 2-year all-cause mortality in real-life patients with type 2 diabetes. Objective This model, now named ENFORCE (EstimatioN oF mORtality risk …
View article: Microvascular Complications Burden Affects Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-Up Study
Microvascular Complications Burden Affects Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-Up Study Open
View article: Influence of high density lipoprotein cholesterol levels on circulating monocytic angiogenic cells functions in individuals with type 2 diabetes mellitus
Influence of high density lipoprotein cholesterol levels on circulating monocytic angiogenic cells functions in individuals with type 2 diabetes mellitus Open
View article: Normoalbuminuric chronic kidney disease in type 1 diabetes: is it real and is it serious? Reply to Rigalleau V, Blanco L, Alexandre L et al [letter]
Normoalbuminuric chronic kidney disease in type 1 diabetes: is it real and is it serious? Reply to Rigalleau V, Blanco L, Alexandre L et al [letter] Open
View article: Pharmacogenetics of oral antidiabetes drugs: evidence for diverse signals at the IRS1 locus
Pharmacogenetics of oral antidiabetes drugs: evidence for diverse signals at the IRS1 locus Open