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View article: Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis
Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis Open
Background Sepsis is a life-threatening condition characterized by organ dysfunction resulting from a dysregulated host response to infection. Sepsis induces systemic inflammation and increases adhesion molecule expression and activation, …
View article: Beta-Blockers as Potential Adjuvants in Melanoma Treatment
Beta-Blockers as Potential Adjuvants in Melanoma Treatment Open
Melanoma, in advanced stages, is the most invasive type of skin cancer, with currently available treatments showing limited efficiency. The number of melanoma cancer cases is expected to increase in the coming years, emphasizing the need f…
View article: Tecnologia Educacional Multidisciplinar para a Educação das Relações Etnicorraciais
Tecnologia Educacional Multidisciplinar para a Educação das Relações Etnicorraciais Open
The Multidisciplinary Educational Technology (TE) “Inspiring Black Women” was created by students of the Specialization Course in Afro-Brazilian and Indigenous Knowledge and Practices in the Amazon at Federal Institute of Pará - Campus Tuc…
View article: NKE-Arduíno - Um Nanokernel Educacional
NKE-Arduíno - Um Nanokernel Educacional Open
This paper presents the development and implementationof NKE-Arduino, an educational multiprogrammable operatingsystem specifically designed for the Arduino platform. Thisproject involved porting the existing NKE system, originallydevelope…
View article: Do Waterborne Nanoplastics Affect the Shore Crab Carcinus maenas? A Case Study with Poly(methyl)methacrylate Particles
Do Waterborne Nanoplastics Affect the Shore Crab Carcinus maenas? A Case Study with Poly(methyl)methacrylate Particles Open
Nanoplastics (NPs) pose a significant environmental threat due to their small sizes, widespread distribution, and bioavailability, enabling interactions with marine organisms from pelagic to benthic species. In this study, the effects of 1…
View article: Bioclimatic Variables Used in Predictive Modeling: A Literature Review for the Caatinga Biome
Bioclimatic Variables Used in Predictive Modeling: A Literature Review for the Caatinga Biome Open
Modeling species distribution is a predictive technique, and its search has increased due to the need to obtain rapid information for decision-making in the face of the loss and fragmentation of natural habitats, climate change, and anthro…
View article: Influence of polystyrene nanoplastics on the toxicity of haloperidol to amphibians: An in vivo and in vitro approach
Influence of polystyrene nanoplastics on the toxicity of haloperidol to amphibians: An in vivo and in vitro approach Open
Chemical pollution is a major driver for the current worldwide crisis of amphibian decline. The present study aimed to assess the influence of polystyrene nanoplastics (PS-NPLs) on the toxicity of haloperidol to aquatic life stages of amph…
View article: The Role of Life Stages in the Sensitivity of Hediste diversicolor to Nanoplastics: A Case Study with Poly(Methyl)Methacrylate (PMMA)
The Role of Life Stages in the Sensitivity of Hediste diversicolor to Nanoplastics: A Case Study with Poly(Methyl)Methacrylate (PMMA) Open
The presence of plastic particles in oceans has been recognized as a major environmental concern. The decrease in particle size increases their ability to directly interact with biota, with particles in the nanometer size range (nanoplasti…
View article: Polyhydroxybutyrate (PHB) nanoparticles modulate metals toxicity in Hydra viridissima
Polyhydroxybutyrate (PHB) nanoparticles modulate metals toxicity in Hydra viridissima Open
The use of bioplastics (e.g., polyhydroxybutyrate) emerged as a solution to help reduce plastic pollution caused by conventional plastics. Nevertheless, bioplastics share many characteristics with their conventional counterparts, such as d…
View article: Optimized Synthesis of Poly(Lactic Acid) Nanoparticles for the Encapsulation of Flutamide
Optimized Synthesis of Poly(Lactic Acid) Nanoparticles for the Encapsulation of Flutamide Open
Biopolymeric nanoparticles (NPs) have gained significant attention in several areas as an alternative to synthetic polymeric NPs due to growing environmental and immunological concerns. Among the most promising biopolymers is poly(lactic a…
View article: Sub-chronic exposure to paroxetine disrupts ecologically relevant behaviours in fish
Sub-chronic exposure to paroxetine disrupts ecologically relevant behaviours in fish Open
The functional conservation of important selective serotonin reuptake inhibitor (SSRI) targets in non-target organisms raises concerns about their potential adverse effects on the ecosystems. Although the environmental levels of SSRIs like…
View article: Short- and long-term toxicity of nano-sized polyhydroxybutyrate to the freshwater cnidarian Hydra viridissima
Short- and long-term toxicity of nano-sized polyhydroxybutyrate to the freshwater cnidarian Hydra viridissima Open
The accumulation of increasingly smaller plastic particles in aquatic ecosystems is a prominent environmental issue and is causing a significant impact on aquatic biota. In response to this challenge, biodegradable plastics have emerged as…
View article: The Number of Ethylene Oxide Groups of Sulphate-Based Surfactants Influences the Cytotoxicity of Mixed Micelles to an Amphibian Cell Line
The Number of Ethylene Oxide Groups of Sulphate-Based Surfactants Influences the Cytotoxicity of Mixed Micelles to an Amphibian Cell Line Open
Sodium lauryl ether sulphate (SLEnS) is an anionic surfactant that is widely used in many fields, such as cosmetics and detergents, among others. This study evaluated the influence of the number of ethylene oxide (EO) units, present in the…
View article: How hazardous can polymethyl methacrylate nanoparticles be to marine polychaetes?
How hazardous can polymethyl methacrylate nanoparticles be to marine polychaetes? Open
The low production costs of plastics have led to their increased use and, ultimately, to their release into the environment, raising concerns about their impact on marine organisms. Polymethyl methacrylate (PMMA) has been used in a wide ra…
View article: Is fish response to nanoplastics exposure modulated by neuropharmaceuticals pre-exposure? A case study with zebrafish (Danio rerio)s
Is fish response to nanoplastics exposure modulated by neuropharmaceuticals pre-exposure? A case study with zebrafish (Danio rerio)s Open
Knowledge on the effects of nanoplastics (NPLs) on freshwater biota has progressed greatly in recent years. However, most of the studies have focused on NPLs individual exposures, a condition that lacks environmental relevance as NPLs do n…
View article: Liprobe, a vital dye for lipid aggregates detection in imaging and high-content screens
Liprobe, a vital dye for lipid aggregates detection in imaging and high-content screens Open
Pathological lipid accumulation is a hallmark of several metabolic disorders, and detection of lipid aggregates is an essential step for initial diagnosis and drug screening purposes. However, low-cost, simple, and reliable detection fluor…
View article: Effects of nanoplastics on zebrafish embryo-larval stages: A case study with polystyrene (PS) and polymethylmethacrylate (PMMA) particles
Effects of nanoplastics on zebrafish embryo-larval stages: A case study with polystyrene (PS) and polymethylmethacrylate (PMMA) particles Open
Plastic production has been rising consistently in the last 30 years and with it, the presence of plastic particles in the environment. A decrease in size often increases the bioavailability and reactivity of the particles. In this study t…
View article: Effects of propranolol and haloperidol on non-target organisms: A case study with amphibians
Effects of propranolol and haloperidol on non-target organisms: A case study with amphibians Open
The technological expansion allowed the development of active substances that promoted an improvement of human life quality and a population increase. However, the increase in the consumption of pharmaceutical substances, in terms of quant…
View article: Non-selective beta-blockers as potential coadjutants for the treatment of prostate cancer
Non-selective beta-blockers as potential coadjutants for the treatment of prostate cancer Open
Prostate cancer is the third most diagnosed cancer worldwide, and the second cause of cancer death in men. Currently available treatments are not always effective. For that reason, new treatment options need to be explored, which may inclu…
View article: Bio-macromolecular detection: new organic vital dyes
Bio-macromolecular detection: new organic vital dyes Open
Aggregates of lipids or proteins are associated with high incidence diseases. The detection of these bio-macromolecules is a key issue in both fundamental research studies and in medical diagnostics. Push-pull chromophores and luminogenic …
View article: Are Crabs Killing the Nation's Salt Marshes?
Are Crabs Killing the Nation's Salt Marshes? Open
The National Estuarine Research Reserve System provides an ideal platform for evaluating the relative importance of different threats to US salt marshes, because vegetation is sampled across all marsh elevations and across many regions. Ou…
View article: Pattern and scale: evaluating generalities in crab distributions and marsh dynamics from small plots to a national scale
Pattern and scale: evaluating generalities in crab distributions and marsh dynamics from small plots to a national scale Open
The generality of ecological patterns depends inextricably on the scale at which they are examined. We investigated patterns of crab distribution and the relationship between crabs and vegetation in salt marshes at multiple scales. By usin…