Mónica Mendes Sousa YOU? Author Swipe

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Referral to liver transplant: a national survey from Portugal Open

Filipe S. Cardoso, Mónica Mendes Sousa, Luís Bagulho, Milena Mendes, Élia Mateus , et al. · 2025

Objectives The referral of patients with cirrhosis to liver transplant (LT) is a multi-stage complex process. There is lack of data on potential challenges to this process. We aimed to characterize challenges faced by Portuguese referring …

Author Correction: Dynamics of CD44+ bovine nucleus pulposus cells with inflammation Open

João N. Ferreira, Joana Caldeira, Mónica Mendes Sousa, Mário A. Barbosa, Meriem Lamghari , et al. · 2025

Análise comparativa da eficiência da tomossíntese em relação à mamografia na detecção do câncer de mama: revisão da literatura Open

Mónica Mendes Sousa, A. Guimarães, Idna de Carvalho Barros Taumaturgo · 2025

Introdução: O câncer de mama é o segunda neoplasia com maior ocorrência entre as mulheres brasileiras. Em virtude disso, exames de imagem como a mamografia e tomossíntese mostram sua relevância associada ao diagnóstico do câncer de mama. O…

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2025

Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities. Whereas peripheral DRG axons regenerate, centr…

Author response: Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2025

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2025

Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities. Whereas peripheral DRG axons regenerate, centr…

Author response: Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2025

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2024

Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities. Whereas peripheral DRG axons regenerate, centr…

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2024

Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities. Whereas peripheral DRG axons regenerate, centr…

Author response: Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2024

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons Open

Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva , et al. · 2024

Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities. Whereas peripheral DRG axons regenerate, centr…

Dynamics of CD44+ bovine nucleus pulposus cells with inflammation Open

João N. Ferreira, Joana Caldeira, Mónica Mendes Sousa, Mário A. Barbosa, Meriem Lamghari , et al. · 2024

Intervertebral Disc (IVD) degeneration has been associated with a chronic inflammatory response, but knowledge on the contribution of distinct IVD cells, namely CD44, to the progression of IVD degeneration remains elusive. Here, bovine nuc…

Beyond a Transmission Cable—New Technologies to Reveal the Richness in Axonal Electrophysiology Open

José C. Mateus, Mónica Mendes Sousa, Juan Burrone, Paulo Aguiar · 2024

The axon is a neuronal structure capable of processing, encoding, and transmitting information. This assessment contrasts with a limiting, but deeply rooted, perspective where the axon functions solely as a transmission cable of somatodend…

Growth rate, evolutionary entropy and ageing across the tree of life Open

Jorge Buescu, Henrique M. Oliveira, Mónica Mendes Sousa · 2023

The growth rate of a population serves as a measure of its Darwinian fitness, while its sensitivity indicates the intensity of selection. Generally, the sensitivity of r decreases with age, resulting in an expected increase in popul…

HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease Open

Sandra Bráz, Marlene M. Morgado, Marta Pereira, Ana C. Monteiro, Olga Golonzhka , et al. · 2023

Introduction In Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine. This neurol…

HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease Open

Sandra Bráz, Marlene M. Morgado, Marta Pereira, Ana Monteiro, Olga Golonzhka , et al. · 2023

In Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, lead to the accumulation of its substrates galactocerebroside and psychosine. This neurologic condition…

Alcohol Consumption Post-Liver Transplantation: A Cross-Sectional Study Open

Carolina Chálim Rebelo, Catarina Félix, Filipe S. Cardoso, Luís Bagulho, Mónica Mendes Sousa , et al. · 2022

Background: Listing patients with alcohol-associated liver disease (ALD) for liver transplant (LT) remains challenging especially due to the risk of alcohol resumption post-LT. We aimed to evaluate post-LT alcohol consumption at a Portugue…

8 The impact of a hands-on nutrition course focus in cardiovascular disease and type 2 diabetes for medical students in Portugal: an observational pilot study Open

Inês Barreiros-Mota, Inês Maldonado, Diana Teixeira, Conceição Calhau, Mónica Mendes Sousa · 2022

Background Physicians have a critical role in promoting healthy behaviors, a cost-effective intervention that results in reduction of disease morbidity and mortality. It is essential that medical students have a nutritional education that …

Neurons contribute to pathology in a mouse model of Krabbe disease in a cell-autonomous manner Open

Pedro Brites, Mónica Mendes Sousa · 2022

In this issue of PLOS Biology, Kreher and colleagues show in a mouse model that in vivo, neurons and not only myelinating glia are primary effectors of disease progression in Krabbe disease. The neuron-specific model generated allows the u…

The Role of Spastin in Axon Biology Open

Ana Catarina Costa, Mónica Mendes Sousa · 2022

Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. …

Sensory neurons have an axon initial segment that initiates spontaneous activity in neuropathic pain Open

Ana Isabel Nascimento, Tiago F. Da Silva, Elisabete C. Fernandes, Liliana L. Luz, Fernando Milhazes Mar , et al. · 2022

The axon initial segment is a specialized compartment of the proximal axon of CNS neurons where action potentials are initiated. However, it remains unknown whether this domain is assembled in sensory dorsal root ganglion neurons, in which…

Supplementary Material for: Alcohol Consumption Post-Liver Transplantation: A Cross-Sectional Study Open

C. ChálimRebelo, Catarina Félix, Cardoso F.S., Luís Bagulho, Mónica Mendes Sousa , et al. · 2022

Background: Listing patients with alcohol-associated liver disease (ALD) for liver transplant (LT) remains challenging especially due to the risk of alcohol resumption post-LT. We aimed to evaluate post-LT alcohol consumption…

Variants in ADD1 cause intellectual disability, corpus callosum dysgenesis, and ventriculomegaly in humans Open

Qi Cai, Irena Feng, Ana Rita Costa, Rita Pinto‐Costa, Jennifer E. Neil , et al. · 2021

Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation Open

Jessica Eira, Joana Magalhães, Nídia Macedo, Maria Elena Pero, Thomas Misgeld , et al. · 2021

Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of function…

The role of the membrane-associated periodic skeleton in axons Open

Ana Rita Costa, Mónica Mendes Sousa · 2021

Transthyretin promotes axon growth via regulation of microtubule dynamics and tubulin acetylation Open

Jessica Eira, Joana Magalhães, Nídia Macedo, Maria Elena Pero, Thomas Misgeld , et al. · 2021

Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. These TTR functions were suggested to underlie its activity in promoting nerve regeneration. While neurons ext…

Variants in ADD1 Cause Intellectual Disability, Corpus Callosum Dysgenesis, and Ventriculomegaly in Humans Open

Qi Cai, Irena Feng, Ana Rita Costa, Rita Pinto‐Costa, Jennifer Neil , et al. · 2021

Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment Open

Ana Rita Costa, Mónica Mendes Sousa · 2020

By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone f…

The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction Open

Ana Rita Costa, Sara Sousa, Rita Pinto‐Costa, José C. Mateus, Cátia D. F. Lopes , et al. · 2020

Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected by spectrin. Here, combining chemical and genetic gain- and loss-of-function assays, we show that in rat hippocampal neurons the MPS is an actomyosin ne…

Author response: The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction Open

Ana Rita Costa, Sara Sousa, Rita Pinto‐Costa, José C. Mateus, Cátia D. F. Lopes , et al. · 2020

Article Figures and data Abstract Introduction Results and discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Neurons have a membrane periodic skele…

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