Monisha Prasad
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View article: Mechanistic Understanding of Finerenone in Hypertension Management: A Narrative Review
Mechanistic Understanding of Finerenone in Hypertension Management: A Narrative Review Open
This review explores the mechanistic role of finerenone, a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, in the management of hypertension. Finerenone exerts its antihypertensive effects by selectively targeting MR pat…
View article: Comment on “The interplay of hypoxia, inflammation, and microbiota as indicators of malignant transformation in oral potentially malignant disorders”
Comment on “The interplay of hypoxia, inflammation, and microbiota as indicators of malignant transformation in oral potentially malignant disorders” Open
View article: Friedelin induces apoptosis in oral cancer: Insights from in vitro and in silico studies
Friedelin induces apoptosis in oral cancer: Insights from in vitro and in silico studies Open
View article: Recent advances in tumor targeted polymeric nanoparticles for HNC treatment: Enhancing therapeutic efficacy via engineered and biocompatible drug delivery systems
Recent advances in tumor targeted polymeric nanoparticles for HNC treatment: Enhancing therapeutic efficacy via engineered and biocompatible drug delivery systems Open
View article: In vitro and Computational Studies of Compounds from Coleus amboinicus against Osteosarcoma
In vitro and Computational Studies of Compounds from Coleus amboinicus against Osteosarcoma Open
View article: Interpreting nirtetralin's anticancer efficacy in oral squamous cell carcinoma: Integrating experimental and computational perspectives
Interpreting nirtetralin's anticancer efficacy in oral squamous cell carcinoma: Integrating experimental and computational perspectives Open
Oral cancer, particularly oral squamous cell carcinoma (OSCC), poses a formidable challenge in global health, urging the quest for innovative therapeutic interventions. Our study delved into exploring the anticancer efficacy of nirtetralin…
View article: Synthesis of Biogenic Silver Nanoparticles using Phyllanthus niruri Extract for Photocatalytic Dye Degradation and Antifungal Applications
Synthesis of Biogenic Silver Nanoparticles using Phyllanthus niruri Extract for Photocatalytic Dye Degradation and Antifungal Applications Open
View article: Investigating the collective advantages of sodium-glucose cotransporter-2 inhibitors and GLP-1 analogs in addressing metabolic health issues linked to obese type 2 diabetes mellitus and related comorbidities
Investigating the collective advantages of sodium-glucose cotransporter-2 inhibitors and GLP-1 analogs in addressing metabolic health issues linked to obese type 2 diabetes mellitus and related comorbidities Open
View article: An update on the molecular mechanisms underlying the progression of miR-21 in oral cancer
An update on the molecular mechanisms underlying the progression of miR-21 in oral cancer Open
View article: Differential Expression of Hard Tissue Proteins in Hypomineralized Second Primary Molars in Comparison to Normal Teeth
Differential Expression of Hard Tissue Proteins in Hypomineralized Second Primary Molars in Comparison to Normal Teeth Open
Objective This study aims to identify the proteins in hypomineralized second primary molars (HSPMs) and correlate their function in Amelogenesis. HSPM is a qualitative defect of the enamel of the second primary molars with no clear etiolog…
View article: Sociogenomics: Gene-environment Interactions in Enamel Defects
Sociogenomics: Gene-environment Interactions in Enamel Defects Open
Sociogenomics, an interdisciplinary field at the intersection of genomics and social sciences, offers a unique lens to understand the complex interplay between genetic predispositions and social/environmental influences on human health. Wh…
View article: Molecular insight into histone methylation as a novel target for oral squamous cell carcinoma: future hope in personalised medicine
Molecular insight into histone methylation as a novel target for oral squamous cell carcinoma: future hope in personalised medicine Open
Oral squamous cell carcinoma (OSCC) is the most prevalent type of malignant epithelial neoplasm that affects the oral cavity. It has been a significant health concern in many countries for a long time since it was usually treated with surg…
View article: Esculetin Loaded Chitosan Nanoparticles (ESC-CNPs) Ameliorates 7, 12 Dimethylbenz [a] Anthracene (DMBA) Induced Breast Cancer in Rat Model
Esculetin Loaded Chitosan Nanoparticles (ESC-CNPs) Ameliorates 7, 12 Dimethylbenz [a] Anthracene (DMBA) Induced Breast Cancer in Rat Model Open
View article: Therapeutic Potential of Bioactive Compounds from Millettia pinnata: Computational and In Vitro Approaches
Therapeutic Potential of Bioactive Compounds from Millettia pinnata: Computational and In Vitro Approaches Open
Osteosarcoma is a very aggressive malignancy mostly of the long bones, including the arms and legs, and is most common in children and young adults. Defined by the uncontrolled proliferation of immature bone cells, this malignancy can lead…
View article: Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review
Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review Open
The incidence of Type-2 Diabetes Mellitus (T2DM) has increased significantly in the last several decades, which is an important challenge for health professionals and researchers. The systems that mediate the interaction between environmen…
View article: Exploring the potential of Rosa chinensis, Rosa cymosa, and Rosa indica in oral disease prevention: A multifaceted approach
Exploring the potential of Rosa chinensis, Rosa cymosa, and Rosa indica in oral disease prevention: A multifaceted approach Open
Introduction: Rose species that are well-known for their therapeutic qualities include Rosa chinensis, Rosa cymosa , and Rosa indica . The study employs in vitro assays and in silico molecular docking to investigate their phytochemical com…
View article: An unusual surgical complication: Slipped molar lodged in vocal cords and its anesthetic management
An unusual surgical complication: Slipped molar lodged in vocal cords and its anesthetic management Open
View article: A new perspective on diagnostic strategies concerning the potential of saliva-based miRNA signatures in oral cancer
A new perspective on diagnostic strategies concerning the potential of saliva-based miRNA signatures in oral cancer Open
Oral cancer, the most prevalent cancer worldwide, is far more likely to occur after the age of forty-five, according to the World Health Organization. Although many biomarkers have been discovered over the years using non-invasive saliva s…
View article: Bridging the gap between epigenetics and cisplatin resistance: Implications for oral cancer management
Bridging the gap between epigenetics and cisplatin resistance: Implications for oral cancer management Open
View article: Unveiling the Potential Role of Glucagon-Like Peptide-1 (Glp-1) Receptor Agonists in Offering Protection of the Cardiovascular, Renal, and Neural Systems: An Updated Narrative Review
Unveiling the Potential Role of Glucagon-Like Peptide-1 (Glp-1) Receptor Agonists in Offering Protection of the Cardiovascular, Renal, and Neural Systems: An Updated Narrative Review Open
Glucagon-like peptide-1 (GLP-1) receptor agonists have drawn a lot of interest lately for their therapeutic advantages over controlling blood sugar levels in the management of type 2 diabetes mellitus (T2DM). This review aims to provide an…
View article: Exploring efferocytosis in oral cancer: Implications for treatment strategies and prognostic insights
Exploring efferocytosis in oral cancer: Implications for treatment strategies and prognostic insights Open
• Efferocytosis, a critical process in maintaining tissue homeostasis. • Tumor cells exploit the efferocytic machinery to evade immune surveillance. • CSCs can hijack the efferocytic process, evading clearance by TAMs and establishing a ni…
View article: Navigating ablation treatment side effects in oral cancer: a call for informed patient care
Navigating ablation treatment side effects in oral cancer: a call for informed patient care Open
Prasad, Monisha; Karobari, Mohmed Isaqali BDS, MSC (Endo), MFDS. RCPS(Galsg), PhD (Endo) Author Information
View article: Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells
Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells Open
View article: Next-generation sequencing (NGS) for the personalized treatment of head and neck squamous cell carcinoma (HNSCC)
Next-generation sequencing (NGS) for the personalized treatment of head and neck squamous cell carcinoma (HNSCC) Open
• Next Generation Sequencing (NGS) identifies genomic mutations in Head and Neck Squamous Cell Carcinoma (HNSCC), guiding personalized treatment approaches. • Customized immunotherapies or targeted treatments based on NGS data may improve …
View article: Decoding the molecular maestros: ADAMs shaping the path of head and neck cancer progression
Decoding the molecular maestros: ADAMs shaping the path of head and neck cancer progression Open
• ADAMs (A Disintegrin And Metalloproteinase) emerges as a central player in the complex narrative of cancer development and advancement • ADAMs facilitate crosstalk between cancer cells and surrounding stromal cells, orchestrating to tumo…
View article: Analysing the Anticancer Properties of Pterostilbene Through Absorption, Distribution, Metabolism, and Excretion (ADME) and Molecular Docking Studies
Analysing the Anticancer Properties of Pterostilbene Through Absorption, Distribution, Metabolism, and Excretion (ADME) and Molecular Docking Studies Open
View article: The potential carbon quantum dots for diagnostic and treatment of oral cancer
The potential carbon quantum dots for diagnostic and treatment of oral cancer Open
• CQDs have high fluorescent nature to recognize the visually. • The small nanoparticles to reach the target cell for diagnostic purposes. • CQDs based drug delivery systems can encapsulate chemotherapeutic agents.
View article: Metal nanocluster-enhanced photoluminescence for head and neck cancer detection: A promising approach
Metal nanocluster-enhanced photoluminescence for head and neck cancer detection: A promising approach Open
• In India, head and neck cancer ranks 2nd in cancer deaths, comprising 10.2% of new cases. • Nanocluster-enhanced photoluminescence aids cancer detection and personalized treatment. • Metal nanoclusters functionalized with cancer-specific…
View article: Exploring the therapeutic effects of seaweed bioactive compounds in oral cancer
Exploring the therapeutic effects of seaweed bioactive compounds in oral cancer Open
• Compounds derived from marine sources have emerged as a promising frontier in cancer research. • Seaweeds contain lot of bioactive compounds. • Bioactive compounds have holding anticancer effect against oral cancer.
View article: Exploring PD-1 methylation in oral cancer: A crucial frontier in immunotherapy
Exploring PD-1 methylation in oral cancer: A crucial frontier in immunotherapy Open
• Programmed Cell Death Protein 1 (PD-1), in regulating immune responses against cancer. • PD-1 is a critical mechanistic player to prevent autoimmunity and maintain peripheral tolerance. • PD-L1, PD-L2 methylation and immune cell infiltra…