Monisha R. Alla
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View article: <i>Chlamydia</i> iron starvation links nutritional immunity to pathogen recognition
<i>Chlamydia</i> iron starvation links nutritional immunity to pathogen recognition Open
Nutritional immunity is an antimicrobial strategy that evolved to starve pathogens of essential nutrients, with death as the desired outcome. Here, we report that transient iron starvation of the obligate intracellular pathogen Chlamydia t…
View article: Host Cell Amplification of Nutritional Stress Contributes To Persistence in Chlamydia trachomatis
Host Cell Amplification of Nutritional Stress Contributes To Persistence in Chlamydia trachomatis Open
Bacteria respond to nutritional stress through universal and unique mechanisms. Genome reduction in the Chlamydiaceae , a consequence of coevolution with their obligate eukaryotic hosts, has reduced their repertoire of stress response mech…
View article: Host cell amplification of nutritional stress contributes to persistence in<i>Chlamydia trachomatis</i>
Host cell amplification of nutritional stress contributes to persistence in<i>Chlamydia trachomatis</i> Open
Persistence, a viable but non-replicating growth state, has been implicated in diseases caused by Chlamydia trachomatis . Starvation of distinct nutrients produce a superficially similar persistent state, implying convergence on a common i…