Montserrat García‐Retortillo
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View article: Isolated IgG elevation in patients with persistently normal transaminases does not affect the outcome of autoimmune hepatitis
Isolated IgG elevation in patients with persistently normal transaminases does not affect the outcome of autoimmune hepatitis Open
View article: Occurrence and Management of Opportunistic Infections in Patients With Autoimmune Hepatitis: A Spanish Multicentre Study
Occurrence and Management of Opportunistic Infections in Patients With Autoimmune Hepatitis: A Spanish Multicentre Study Open
Background The management of autoimmune hepatitis (AIH) is based on immunosuppressive agents that may increase the risk of opportunistic infections (OI). However, data on their prevalence and incidence are lacking, which may explain the ab…
View article: Development and pilot evaluation of an evidence-based algorithm for MASLD (formerly NAFLD) management in primary care in Europe
Development and pilot evaluation of an evidence-based algorithm for MASLD (formerly NAFLD) management in primary care in Europe Open
Background Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), emerges as major cause of morbidity and mortality globally, with chronic patients facing increased risk. Guidelines on MASLD management in primary…
View article: Towards Value Awareness in the Medical Field
Towards Value Awareness in the Medical Field Open
View article: Further decompensation in cirrhosis: Results of a large multicenter cohort study supporting Baveno VII statements
Further decompensation in cirrhosis: Results of a large multicenter cohort study supporting Baveno VII statements Open
Background and Aims: The prognostic weight of further decompensation in cirrhosis is still unclear. We investigated the incidence of further decompensation and its effect on mortality in patients with cirrhosis. Approach and Results: Multi…
View article: Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study
Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study Open
View article: Correction: LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
Correction: LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries Open
View article: Development and implementation of a continuing medical education program on non-alcoholic fatty liver disease for primary care practitioners in Europe
Development and implementation of a continuing medical education program on non-alcoholic fatty liver disease for primary care practitioners in Europe Open
Background Primary care has a crucial role to play in the prevention, early detection, referral, and risk factor management of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NAFLD/NASH). In 2021, a team of European co…
View article: Tenofovir Disoproxil Fumarate Reduces the Severity of COVID-19 in Patients with Chronic Hepatitis B
Tenofovir Disoproxil Fumarate Reduces the Severity of COVID-19 in Patients with Chronic Hepatitis B Open
View article: Global Real-World Evidence of Sofosbuvir/Velpatasvir as a Highly Effective Treatment and Elimination Tool in People with Hepatitis C Infection Experiencing Mental Health Disorders
Global Real-World Evidence of Sofosbuvir/Velpatasvir as a Highly Effective Treatment and Elimination Tool in People with Hepatitis C Infection Experiencing Mental Health Disorders Open
Hepatitis C virus (HCV) is prevalent in people with mental health disorders, a priority population to diagnose and cure in order to achieve HCV elimination. This integrated analysis pooled data from 20 cohorts in seven countries to evaluat…
View article: LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries Open
View article: Should we seek complete liver tests normalization in primary biliary cholangitis? Data from ColHai registry
Should we seek complete liver tests normalization in primary biliary cholangitis? Data from ColHai registry Open
View article: Follow‐up evaluation of patients with liver test abnormalities detected during <scp>SARS‐CoV2</scp> infection
Follow‐up evaluation of patients with liver test abnormalities detected during <span>SARS‐CoV2</span> infection Open
Abnormal liver function tests (A‐LFTs) during admission for coronavirus disease‐19 (COVID‐19) are frequent, but its evolution after COVID‐19 resolution remains unexplored. We evaluated factors related to A‐LFTs during COVID‐19 and assessed…
View article: Effect of rifaximin on infections, acute‐on‐chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA‐AH)
Effect of rifaximin on infections, acute‐on‐chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA‐AH) Open
Background & Aims Alcoholic hepatitis (AH) is associated with a high incidence of infection and mortality. Rifaximin reduces bacterial overgrowth and translocation. We aimed to study whether the administration of rifaximin as an adjuvant t…
View article: On-therapy HBsAg kinetics can predict HBsAg loss after nucleos(t)ide analogues interruption in HBeAg-negative patients. The cup is half full and half empty
On-therapy HBsAg kinetics can predict HBsAg loss after nucleos(t)ide analogues interruption in HBeAg-negative patients. The cup is half full and half empty Open
View article: Microwave versus radiofrequency ablation for the treatment of liver malignancies: a randomized controlled phase 2 trial
Microwave versus radiofrequency ablation for the treatment of liver malignancies: a randomized controlled phase 2 trial Open
Microwave (MWA) and radiofrequency ablation (RFA) are main ablative techniques for hepatocellular carcinoma (HCC) and colorectal liver metastasis (MT). This randomized phase 2 clinical trial compares the effectiveness of MWA and RFA as wel…
View article: Noninvasive Prediction of Outcomes in Autoimmune Hepatitis–Related Cirrhosis
Noninvasive Prediction of Outcomes in Autoimmune Hepatitis–Related Cirrhosis Open
The value of noninvasive tools in the diagnosis of autoimmune hepatitis (AIH)–related cirrhosis and the prediction of clinical outcomes is largely unknown. We sought to evaluate (1) the utility of liver stiffness measurement (LSM) in the d…
View article: Global real-world evidence of sofosbuvir/velpatasvir (SOF/VEL) as a highly effective treatment in underserved patient populations because of mental health disorders, incarceration or homelessness
Global real-world evidence of sofosbuvir/velpatasvir (SOF/VEL) as a highly effective treatment in underserved patient populations because of mental health disorders, incarceration or homelessness Open
Introduction and Objectives: The treatment of vulnerable populations must be prioritized to accomplish the WHO HCV elimination goals by 2030, including patients with mental health disorders, incarcerated patients or homeless patients. Simp…
View article: Real-World Evidence of Sofosbuvir/Velpatasvir as an Effective and Simple Hepatitis C Virus Treatment and Elimination Tool in Homeless Populations
Real-World Evidence of Sofosbuvir/Velpatasvir as an Effective and Simple Hepatitis C Virus Treatment and Elimination Tool in Homeless Populations Open
Lay abstract Reducing the prevalence of HCV in people experiencing homelessness is an important step toward elimination of viral hepatitis as a major public health threat. However, several patient and social factors can complicate treatmen…
View article: Early Hypertransaminasemia after Kidney Transplantation: Significance and Evolution According to Donor Type
Early Hypertransaminasemia after Kidney Transplantation: Significance and Evolution According to Donor Type Open
Early hypertransaminasemia after kidney transplantation (KT) is frequent. It has been associated with the crosstalk produced between the liver and the kidney in ischemia-reperfusion situations. However, the influence of the donor type has …
View article: Worse outcome and distinct mutational pattern in follicular lymphoma with anti-HBc positivity
Worse outcome and distinct mutational pattern in follicular lymphoma with anti-HBc positivity Open
Epidemiological studies have demonstrated the association between hepatitis B virus (HBV) infection and B-cell non–Hodgkin lymphoma (NHL), mainly for diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). We studied a cohort o…
View article: Population screening for liver fibrosis: Toward early diagnosis and intervention for chronic liver diseases
Population screening for liver fibrosis: Toward early diagnosis and intervention for chronic liver diseases Open
Cirrhosis, highly prevalent worldwide, develops after years of hepatic inflammation triggering progressive fibrosis. Currently, the main etiologies of cirrhosis are non‐alcoholic fatty liver disease and alcohol‐related liver disease, altho…
View article: Hepatitis B surface antigen and hepatitis B core-related antigen kinetics after adding pegylated-interferon to nucleos(t)ids analogues in hepatitis B e antigen-negative patients
Hepatitis B surface antigen and hepatitis B core-related antigen kinetics after adding pegylated-interferon to nucleos(t)ids analogues in hepatitis B e antigen-negative patients Open
The addition of Peg-IFN to NAs caused a greater and faster decrease of HBsAg levels compared to NA therapy. Side effects of Peg-IFN can limit its use in clinical practice.
View article: Efficacy and safety of treatment interruption in patients with HBeAg negative chronic hepatitis B
Efficacy and safety of treatment interruption in patients with HBeAg negative chronic hepatitis B Open
View article: Global real-world evidence of sofosbuvir/velpatasvir (SOF/VEL) as a highly effective treatment and elimination tool in underserved patient populations experiencing mental health disorders, incarceration or homelessness
Global real-world evidence of sofosbuvir/velpatasvir (SOF/VEL) as a highly effective treatment and elimination tool in underserved patient populations experiencing mental health disorders, incarceration or homelessness Open
View article: Expansion of a multidisciplinary support program for patients with addictions and hepatitis C: strategies for an effective approach
Expansion of a multidisciplinary support program for patients with addictions and hepatitis C: strategies for an effective approach Open
View article: Prevention of hepatitis B virus reactivation in lymphoma patients
Prevention of hepatitis B virus reactivation in lymphoma patients Open
View article: Correction: Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study
Correction: Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study Open
[This corrects the article DOI: 10.1371/journal.pone.0184550.].
View article: Quantification of HBsAg to predict low levels and seroclearance in HBeAg-negative patients receiving nucleos(t)ide analogues
Quantification of HBsAg to predict low levels and seroclearance in HBeAg-negative patients receiving nucleos(t)ide analogues Open
Reduction of qHBsAg is slow in HBeAg-negative patients receiving NAs, although low levels or faster qHBsAg decline may occur in 14%. A qHBsAg reduction >0.3 log IU/mL at year 3 can identify patients with a higher probability of achieving l…
View article: Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study
Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study Open
In patients with hematological malignancy and resolved hepatitis B infection receiving RTX-based regimens, HBV reactivation did not occur in patients given TDF prophylaxis.