Morin Beyeler
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View article: Anticoagulant versus antiplatelet treatment for secondary stroke prevention in patients with active cancer
Anticoagulant versus antiplatelet treatment for secondary stroke prevention in patients with active cancer Open
Background Approximately 5–10% of patients with acute ischemic stroke (AIS) have known active cancer. These patients are at high risk for both recurrent AIS and major bleeding. The optimal antithrombotic strategy for cancer-related stroke …
View article: Focal Hypoperfusion on Baseline Perfusion-Weighted MRI and the Risk of Subsequent Cerebrovascular Events in Patients With TIA
Focal Hypoperfusion on Baseline Perfusion-Weighted MRI and the Risk of Subsequent Cerebrovascular Events in Patients With TIA Open
Focal hypoperfusion on acute PWI MRI was found in 1 in 5 patients with TIA. It was associated with a higher incidence of AIS during long-term follow-up, especially when within the expected TIA territory. Further research is needed to clari…
View article: Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use
Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use Open
BACKGROUND: Intravenous thrombolysis (IVT) in patients with recent ingestion of direct oral anticoagulants (DOACs) is a frequent challenge and remains controversial. The benefit of DOAC reversal before IVT is uncertain. METHODS: Using targ…
View article: History of Cancer and Atrial Cardiopathy: A Secondary Analysis of the ARCADIA Clinical Trial
History of Cancer and Atrial Cardiopathy: A Secondary Analysis of the ARCADIA Clinical Trial Open
Background Approximately 50% of strokes in patients with cancer are classified as cryptogenic after standard evaluation. Atrial cardiopathy could explain some cancer‐related cryptogenic strokes. However, the relationship between cancer and…
View article: Susceptibility Vessel Sign and Intravenous Alteplase in Stroke Patients Treated with Thrombectomy
Susceptibility Vessel Sign and Intravenous Alteplase in Stroke Patients Treated with Thrombectomy Open
View article: How Good Are Neurologists? A Diagnostic Accuracy Study on the Performance of Neurologists in the Emergency Room
How Good Are Neurologists? A Diagnostic Accuracy Study on the Performance of Neurologists in the Emergency Room Open
Background In people with suspected stroke the first assessment occurs under time pressure in the emergency department and is based solely on clinical information. Working hypotheses include mechanism and localization of the clinical defic…
View article: Recanalization Outcomes and Procedural Complications in Patients With Acute Ischemic Stroke and COVID-19 Receiving Endovascular Treatment
Recanalization Outcomes and Procedural Complications in Patients With Acute Ischemic Stroke and COVID-19 Receiving Endovascular Treatment Open
View article: Field-testing the explicit diagnostic criteria for transient ischemic attack: a diagnostic accuracy study
Field-testing the explicit diagnostic criteria for transient ischemic attack: a diagnostic accuracy study Open
Background and aim Explicit diagnostic criteria for transient ischemic attack (TIA) (EDCT) have been recently proposed based on the assumption, that a migraine aura-like symptom is not typical for a TIA. However, migraine-like symptoms hav…
View article: Uptake of Dual Antiplatelet Therapy After High-Risk Transient Ischemic Attack at a University Hospital
Uptake of Dual Antiplatelet Therapy After High-Risk Transient Ischemic Attack at a University Hospital Open
Multiple randomized controlled trials have demonstrated that dual antiplatelet therapy (DAPT) significantly reduces the risk of subsequent stroke as compared to aspirin monotherapy after high-risk transient ischemic attack (TIA) or minor i…
View article: Apixaban vs Aspirin in Patients With Cancer and Cryptogenic Stroke
Apixaban vs Aspirin in Patients With Cancer and Cryptogenic Stroke Open
Importance Approximately 10% to 15% of ischemic strokes are associated with cancer; cancer-associated stroke, particularly when cryptogenic, is associated with high rates of recurrent stroke and major bleeding. Limited data exist on the sa…
View article: Mortality in acute ischemic stroke patients with new cancer diagnosed during the index hospitalization versus after discharge
Mortality in acute ischemic stroke patients with new cancer diagnosed during the index hospitalization versus after discharge Open
View article: Factors impacting D-dimer levels in patients with acute ischemic cerebrovascular events
Factors impacting D-dimer levels in patients with acute ischemic cerebrovascular events Open
The time from symptom onset may affect D-dimer levels in patients with AIS but not those with TIA. Further studies confirming these findings and validating time-specific variations are needed to enable D-dimer levels to be used efficiently…
View article: Atrial fibrillation and short-term outcomes after cancer-related ischemic stroke
Atrial fibrillation and short-term outcomes after cancer-related ischemic stroke Open
Introduction: Atrial fibrillation (AF) and cancer are each associated with worse outcomes in patients with acute ischemic stroke (AIS). Few studies have evaluated the impact of AF on outcomes of cancer-related stroke. Patients and methods:…
View article: Intravenous thrombolysis in patients with recent intake of direct oral anticoagulants: A target trial analysis after the liberalization of institutional guidelines
Intravenous thrombolysis in patients with recent intake of direct oral anticoagulants: A target trial analysis after the liberalization of institutional guidelines Open
Introduction: This study aimed to report the safety and efficacy of off-label intravenous thrombolysis (IVT) with alteplase after sequentially liberalizing our institutional guidelines allowing IVT for patients under direct oral anticoagul…
View article: Frequency of ischaemic stroke and intracranial haemorrhage in patients with reversible cerebral vasoconstriction syndrome (<scp>RCVS</scp>) and posterior reversible encephalopathy syndrome (<scp>PRES</scp>) – A systematic review
Frequency of ischaemic stroke and intracranial haemorrhage in patients with reversible cerebral vasoconstriction syndrome (<span>RCVS</span>) and posterior reversible encephalopathy syndrome (<span>PRES</span>) – A systematic review Open
Background Posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) may cause ischaemic stroke and intracranial haemorrhage. The aim of our study was to assess the frequency of the afore‐…
View article: Characteristics of acute ischemic stroke and unusual aura in patients with migraine with aura
Characteristics of acute ischemic stroke and unusual aura in patients with migraine with aura Open
Background Sometimes migraine aura changes from attack to attack, raising the question of whether the change is heralding an ischemic stroke or an unusual aura. Differentiating unusual migraine aura from the onset of an acute ischemic stro…
View article: Effect of Asymptomatic and Symptomatic COVID-19 on Acute Ischemic Stroke Revascularization Outcomes
Effect of Asymptomatic and Symptomatic COVID-19 on Acute Ischemic Stroke Revascularization Outcomes Open
BACKGROUND: The association of COVID-19 with higher bleeding risk and worse outcomes in acute ischemic stroke (AIS) undergoing revascularization may be related to the presence of infection symptoms. We aimed to assess the safety and outcom…
View article: Transient ischemic attacks in patients with active and occult cancer
Transient ischemic attacks in patients with active and occult cancer Open
Background and aim Paraneoplastic coagulopathy can present as stroke and is associated with specific biomarker changes. Identifying paraneoplastic coagulopathy can help guide secondary prevention in stroke patients, and early cancer detect…
View article: Long-Term Effect of Mechanical Thrombectomy in Stroke Patients According to Advanced Imaging Characteristics.
Long-Term Effect of Mechanical Thrombectomy in Stroke Patients According to Advanced Imaging Characteristics. Open
View article: Small vessel disease burden and risk of recurrent cerebrovascular events in patients with lacunar stroke and intracerebral haemorrhage attributable to deep perforator arteriolopathy
Small vessel disease burden and risk of recurrent cerebrovascular events in patients with lacunar stroke and intracerebral haemorrhage attributable to deep perforator arteriolopathy Open
Introduction: Deep perforator arteriolopathy (DPA) causes intracerebral haemorrhage (ICH) and lacunar strokes (LS). We compare patient characteristics, MRI findings and clinical outcomes among patients with deep ICH and LS. Patients and me…
View article: Correction: Changes of migraine aura with advancing age of patients
Correction: Changes of migraine aura with advancing age of patients Open
View article: Changes of migraine aura with advancing age of patients
Changes of migraine aura with advancing age of patients Open
Aim Given the similar presentation of migraine aura and acute ischemic stroke, advancing patient age might change the characteristics of migraine with aura (MA) and be clinically important. Clinical data, however, are limited. Experimental…
View article: Intra-Arterial Thrombolysis is Associated with Delayed Reperfusion of Remaining Vessel Occlusions following Incomplete Thrombectomy
Intra-Arterial Thrombolysis is Associated with Delayed Reperfusion of Remaining Vessel Occlusions following Incomplete Thrombectomy Open
Rescue intra-arterial thrombolytics is associated with delayed reperfusion of remaining vessel occlusions following incomplete mechanical thrombectomy. The value of intra-arterial thrombolytics as a potential therapy for incomplete reperfu…
View article: Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial
Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial Open
BACKGROUND: Evidence-based hemostatic treatment for intracerebral hemorrhage (ICH) associated with non–vitamin K antagonist oral anticoagulants (NOACs) is lacking. Tranexamic acid (TXA) is an antifibrinolytic drug potentially limiting hema…
View article: IV Thrombolysis With or Without Endovascular Treatment for Suspected Ischemic Stroke in Patients With Intracranial Tumors
IV Thrombolysis With or Without Endovascular Treatment for Suspected Ischemic Stroke in Patients With Intracranial Tumors Open
In our dataset from routine clinical care, we provide insights on the safety of IVT for suspected ischemic stroke in patients with intracranial tumors, a population that is commonly withheld thrombolysis in clinical practice and prospectiv…
View article: Correction to: Factors associated with migraine aura-like symptoms in acute ischemic stroke
Correction to: Factors associated with migraine aura-like symptoms in acute ischemic stroke Open
View article: Impact of sex in stroke in the young
Impact of sex in stroke in the young Open
Background and purpose Limited data is available on sex differences in young stroke patients describing discrepant findings. This study aims to investigate the sex differences in young stroke patients. Methods Prospective cohort study comp…
View article: Prediction of delayed reperfusion in patients with incomplete reperfusion following thrombectomy
Prediction of delayed reperfusion in patients with incomplete reperfusion following thrombectomy Open
Background: The clinical course of patients with incomplete reperfusion after thrombectomy, defined as an expanded Thrombolysis in Cerebral Infarction (eTICI) score of 2a–2c, is heterogeneous. Patients showing delayed reperfusion (DR) have…
View article: Absence of susceptibility vessel sign and hyperdense vessel sign in patients with cancer-related stroke
Absence of susceptibility vessel sign and hyperdense vessel sign in patients with cancer-related stroke Open
Background and aim Identification of paraneoplastic hypercoagulability in stroke patients helps to guide investigations and prevent stroke recurrence. A previous study demonstrated an association between the absence of the susceptibility v…
View article: Abstract Number ‐ 184: Prediction Model For Medical Rescue Treatment Strategies In Patients With Incomplete Reperfusion
Abstract Number ‐ 184: Prediction Model For Medical Rescue Treatment Strategies In Patients With Incomplete Reperfusion Open
Introduction After successful reperfusion is achieved (extended Thrombolysis in Cerebral Infarction (eTICI) ≥ 2b50), decision on pursuing additional treatment strategies in order to achieve complete reperfusion (eTICI = 2c/3), is multifact…