Moritz Kaths
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View article: Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability
Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability Open
Purpose The prognosis of patients with metastatic GIST and imatinib-sensitive primary mutations has significantly improved. However, limited data are available to inform patients about outcomes across different lines of treatment. This ret…
View article: Lymph Node Staging in Perihilar Cholangiocarcinoma: The Key to the Big Picture
Lymph Node Staging in Perihilar Cholangiocarcinoma: The Key to the Big Picture Open
Klatskin tumors have a bad prognosis despite aggressive therapy. The role and extent of lymph node dissection during surgery is a matter of discussion. This retrospective study analyzes our current experience of surgical treatments in the …
View article: Plasma Sequencing for Patients with GIST—Limitations and Opportunities in an Academic Setting
Plasma Sequencing for Patients with GIST—Limitations and Opportunities in an Academic Setting Open
Circulating tumor DNA (ctDNA) from circulating free DNA (cfDNA) in GIST is of interest for the detection of heterogeneous resistance mutations and treatment monitoring. However, methodologies for use in a local setting are not standardized…
View article: HTK‐N as a new preservation solution for human kidney preservation: Results of a pilot randomized controlled clinical phase II trial in living donor transplantation
HTK‐N as a new preservation solution for human kidney preservation: Results of a pilot randomized controlled clinical phase II trial in living donor transplantation Open
Background HTK‐N was developed based on the traditional HTK preservation solution, resulting in stronger protection against reactive oxygen species as well as better tolerance to hypothermia and ischemia. Aim of the present study was to co…
View article: Clinical use of controlled oxygenated rewarming of kidney grafts prior to transplantation by ex vivo machine perfusion. A pilot study
Clinical use of controlled oxygenated rewarming of kidney grafts prior to transplantation by ex vivo machine perfusion. A pilot study Open
Background Sudden restoration of normothermic conditions upon reperfusion of cold‐stored grafts has been suggested to entail a massive energy demand not yet met by the cells that still suffer from hypothermic torpor. An adapted and gentle …
View article: Controlled Oxygenated Rewarming Compensates for Cold Storage–induced Dysfunction in Kidney Grafts
Controlled Oxygenated Rewarming Compensates for Cold Storage–induced Dysfunction in Kidney Grafts Open
Background. Normothermic machine perfusion (NMP) provides a promising strategy for preservation and conditioning of marginal organ grafts. However, at present, high logistic effort limits normothermic renal perfusion to a short, postponed …
View article: Should We Exclude Live Donor Liver Transplantation for Liver Transplant Recipients Requiring Mechanical Ventilation and Intensive Care Unit Care?
Should We Exclude Live Donor Liver Transplantation for Liver Transplant Recipients Requiring Mechanical Ventilation and Intensive Care Unit Care? Open
The LDLT may provide a faster access to transplantation and therefore, offers an alternative treatment option for critically ill patients requiring ICU care and mechanical ventilation support at the time of transplantation.