Moritz Meusel
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View article: Clinical characteristics and BGA-optimized pretest probability of pulmonary embolism in the elderly
Clinical characteristics and BGA-optimized pretest probability of pulmonary embolism in the elderly Open
Background Pulmonary arterial embolism (PE) is not well characterized in elderly patients. In addition, unnecessary computed tomography pulmonary angiography (CTPA) examinations are often performed within this patient group, especially if …
View article: Myocardial injury and clinical outcome in octogenarians after non–ST-elevation myocardial infarction
Myocardial injury and clinical outcome in octogenarians after non–ST-elevation myocardial infarction Open
Introduction The aim of this study was to analyze age-associated myocardial injury and clinical outcome after non-ST-elevation myocardial infarction (NSTEMI). Methods This prospective, multicenter study consists of 440 patients with NSTEMI…
View article: The Platelet Anaphylatoxin Receptor C5aR1 (CD88) Is a Promising Target for Modulating Vessel Growth in Response to Ischemiaa
The Platelet Anaphylatoxin Receptor C5aR1 (CD88) Is a Promising Target for Modulating Vessel Growth in Response to Ischemiaa Open
© . The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. …
View article: Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor–modulating factors
Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor–modulating factors Open
In ischemic tissue, platelets can modulate angiogenesis. The specific factors influencing this function, however, are poorly understood. Here, we characterized the complement anaphylatoxin C5a-mediated activation of C5a receptor 1 (C5aR1) …
View article: PrEdictive value of coMbined pre-test proBability and blOod gas anaLysis In pulmonary emboliSM—the EMBOLISM study
PrEdictive value of coMbined pre-test proBability and blOod gas anaLysis In pulmonary emboliSM—the EMBOLISM study Open
View article: JUUL™ing and Heating Lead to a Worsening of Arterial Stiffness
JUUL™ing and Heating Lead to a Worsening of Arterial Stiffness Open
Background: The widespread use of the JUUL™ device ignited a discussion about the effects these products have on harm reduction. Therefore, we conducted a study directly comparing the JUUL™ device with a cigarette, a heated tobacco product…
View article: Measurement of Blood Pressure by Ultrasound—The Applicability of Devices, Algorithms and a View in Local Hemodynamics
Measurement of Blood Pressure by Ultrasound—The Applicability of Devices, Algorithms and a View in Local Hemodynamics Open
Objective: Due to ongoing technical progress, the ultrasonic measurement of blood pressure (BP) as an alternative to oscillometric measurement (NIBP) or the continuous non-invasive arterial pressure method (CNAP) moves further into focus. …
View article: The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets
The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets Open
Platelets contribute to the regulation of tissue neovascularization, although the specific factors underlying this function are unknown. Here, we identified the complement anaphylatoxin C5a-mediated activation of C5a receptor 1 (C5aR1) on …
View article: Microcirculation in Patients with Takotsubo Syndrome—The Prospective CIRCUS-TTS Study
Microcirculation in Patients with Takotsubo Syndrome—The Prospective CIRCUS-TTS Study Open
The pathophysiology of Takotsubo syndrome (TTS) is incompletely understood. A sympathetic overdrive with coronary microvascular dysfunction might play a central role. The aim of our study was to assess the status of the systemic microcircu…
View article: Differential Effects of Angiotensin-II Compared to Phenylephrine on Arterial Stiffness and Hemodynamics: A Placebo-Controlled Study in Healthy Humans
Differential Effects of Angiotensin-II Compared to Phenylephrine on Arterial Stiffness and Hemodynamics: A Placebo-Controlled Study in Healthy Humans Open
The α1-adrenoceptor agonist phenylephrine (PE) and Angiotensin II (Ang II) are both potent vasoconstrictors at peripheral resistance arteries. PE has pure vasoconstrictive properties. Ang II, additionally, modulates central nervous blood p…
View article: Prognostic Value of Different CMR-Based Techniques to Assess Left Ventricular Myocardial Strain in Takotsubo Syndrome
Prognostic Value of Different CMR-Based Techniques to Assess Left Ventricular Myocardial Strain in Takotsubo Syndrome Open
Cardiac magnetic resonance (CMR)-derived left ventricular (LV) global longitudinal strain (GLS) provides incremental prognostic information on various cardiovascular diseases but has not yet been investigated comprehensively in patients wi…
View article: Impact of Morphine Treatment on Infarct Size and Reperfusion Injury in Acute Reperfused ST-Elevation Myocardial Infarction
Impact of Morphine Treatment on Infarct Size and Reperfusion Injury in Acute Reperfused ST-Elevation Myocardial Infarction Open
Current evidence regarding the effect of intravenous morphine administration on reperfusion injury and/or cardioprotection in patients with myocardial infarction is conflicting. The aim of this study was to evaluate the impact of morphine …
View article: GHRH-mediated GH release is associated with sympathoactivation and baroreflex resetting: a microneurographic study in healthy humans
GHRH-mediated GH release is associated with sympathoactivation and baroreflex resetting: a microneurographic study in healthy humans Open
Previous research suggested substantial interactions of growth hormone (GH) and sympathetic nervous activity. This cross talk can be presumed both during physiological (e.g., slow-wave sleep) and pathological conditions of GH release. Howe…
View article: E-cigarettes and cigarettes worsen peripheral and central hemodynamics as well as arterial stiffness: A randomized, double-blinded pilot study
E-cigarettes and cigarettes worsen peripheral and central hemodynamics as well as arterial stiffness: A randomized, double-blinded pilot study Open
The introduction of electronic cigarettes has led to widespread discussion on the cardiovascular risks compared to conventional smoking. We therefore conducted a randomized cross-over study of the acute use of three tobacco products, inclu…
View article: Thermoregulatory and Cardiovascular Consequences of a Transient Thyrotoxicosis and Recovery in Male Mice
Thermoregulatory and Cardiovascular Consequences of a Transient Thyrotoxicosis and Recovery in Male Mice Open
Thyroid hormones play a major role in body homeostasis, regulating energy expenditure and cardiovascular function. Given that obese people or athletes might consider rapid weight loss as beneficial, voluntary intoxication with T4 preparati…