Moritz Sander
YOU?
Author Swipe
View article: Secondary malignancy of T-cell origin after CAR T-cell therapy: EMA’s conclusions from the evaluation of 38 suspected cases
Secondary malignancy of T-cell origin after CAR T-cell therapy: EMA’s conclusions from the evaluation of 38 suspected cases Open
This article provides a regulatory perspective on secondary malignancy of T-cell origin as a rare adverse reaction to the currently marketed CD19- or BCMA-directed chimeric antigen receptor (CAR) T-cell therapies. To assess the risk, causa…
View article: The miRNA<i>bantam</i>regulates growth and tumorigenesis by repressing the cell cycle regulator<i>tribbles</i>
The miRNA<i>bantam</i>regulates growth and tumorigenesis by repressing the cell cycle regulator<i>tribbles</i> Open
One of the fundamental issues in biology is understanding how organ size is controlled. Tissue growth has to be carefully regulated to generate well-functioning organs, and defects in growth control can result in tumor formation. The Hippo…
View article: Oncogenic cooperation between Yorkie and the conserved microRNA<i>miR-8</i>in the wing disc of<i>Drosophila</i>
Oncogenic cooperation between Yorkie and the conserved microRNA<i>miR-8</i>in the wing disc of<i>Drosophila</i> Open
Tissue growth has to be carefully controlled to generate well-functioning organs. microRNAs are small noncoding RNAs that modulate the activity of target genes and play a pivotal role in animal development. Understanding the functions of m…