Mosab Ali Awadelkareem YOU? Author Swipe

Last 10y

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates Open

Valentina Davì, Pierre Parutto, Cécile C. Crapart, Yingxin Zhang, Tasuku Konno , et al. · 2025

The endoplasmic reticulum (ER)'s continuous morphology is tightly controlled by ER-shaping proteins, whose genetic or expression defects drive a spectrum of neurodegenerative disorders from Hereditary Spastic Paraplegia to Alzheimer's dise…

Strengthening Africa’s brain health and economic resilience Open

Mie Rizig, Connor McLaughlin, Vaibhav A. Narayan, Mohamed Salama, Chinedu Udeh‐Momoh , et al. · 2025

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport Open

Tasuku Konno, Pierre Parutto, Cécile C. Crapart, Valentina Davì, David M. Bailey , et al. · 2024

Cell functions rely on intracellular transport systems distributing bioactive molecules with high spatiotemporal accuracy. The endoplasmic reticulum (ER) tubular network constitutes a system for delivering luminal solutes, including Ca

A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons Open

Jimena Pérez-Sánchez, Steven J. Middleton, Luke A. Pattison, Helen Hilton, Mosab Ali Awadelkareem , et al. · 2023

Hyperexcitability in sensory neurons is known to underlie many of the maladaptive changes associated with persistent pain. Chemogenetics has shown promise as a means to suppress such excitability, yet chemogenetic approaches suitable for h…

Inhibition of sensory neuron driven acute, inflammatory, and neuropathic pain using a humanised chemogenetic system Open

Jimena Pérez-Sánchez, Steven J. Middleton, Luke A. Pattison, Helen Hilton, Mosab Ali Awadelkareem , et al. · 2023

North and East African mitochondrial genetic variation needs further characterization towards precision medicine Open

Anke Fähnrich, Isabel Stephan, Misa Hirose, Franziska Haarich, Mosab Ali Awadelkareem , et al. · 2023

Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP Open

Eduardo P. Melo, Tasuku Konno, Ilaria Farace, Mosab Ali Awadelkareem, Lise R. Skov , et al. · 2022

North and East African mitochondrial genetic variation needs further characterization towards precision medicine Open

Anke Fähnrich, Isabel Stephan, Misa Hirose, Franziska Haarich, Mosab Ali Awadelkareem , et al. · 2021

Introduction Mitochondria are maternally inherited cell organelles with their own genome, and perform various functions in eukaryotic cells such as energy production and cellular homeostasis. Due to their inheritance and manifold biologica…

Two decades of neuroscience publication trends in Africa Open

Mahmoud Bukar Maina, Umar Ahmad, Ibrahim Harun Arrashid, SALIHU HAMIDU, Fayza Eid Nasr , et al. · 2021

Endoplasmic Reticulum morphological regulation by RTN4/NOGO modulates neuronal regeneration by curbing luminal transport Open

Tasuku Konno, Pierre Parutto, David M. Bailey, Valentina Davì, Cécile C. Crapart , et al. · 2021

Cell and tissue functions rely on an elaborate intracellular transport system responsible for distributing bioactive molecules with high spatiotemporal accuracy. The tubular network of the Endoplasmic Reticulum (ER) constitutes a system fo…

Stress-induced protein disaggregation in the Endoplasmic Reticulum catalysed by BiP Open

Eduardo P. Melo, Ilaria Farace, Tasuku Konno, Mosab Ali Awadelkareem, Lise R. Skov , et al. · 2021

Protein synthesis is supported by cellular machineries that ensure polypeptides fold to their native three-dimensional conformation with high fidelity whilst eliminating misfolded, aggregation-prone species. While protein aggregates can co…

TReND in Africa: Toward a Truly Global (Neuro)science Community Open

Tom Baden, Mahmoud Bukar Maina, André Maia Chagas, Yunusa Garba Mohammed, Thomas O. Auer , et al. · 2020

African neuroscience on the global stage: Nigeria as a model Open

Mahmoud Bukar Maina, Yunusa Garba Mohammed, Ali Maina Bukar, Umar Ahmad, Abubakar Tijjani Salihu , et al. · 2019

Of the 572 neuroscience-related studies published in Nigerian from 1996 to 2017, <5% used state-of-the-art techniques, none used transgenic models, and only one study was published in a top-tier journal.