Moshe Hoshen
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View article: Epidemiology of hepatitis delta virus (HDV) infection and comparison of clinical characteristics and disease progression among patients with HDV vs. hepatitis B mono-infection: real-world data from a large healthcare insurer-provider in Israel
Epidemiology of hepatitis delta virus (HDV) infection and comparison of clinical characteristics and disease progression among patients with HDV vs. hepatitis B mono-infection: real-world data from a large healthcare insurer-provider in Israel Open
Not applicable.
View article: Data from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort
Data from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort Open
Background:Ferritin, an iron storage protein and acute phase reactant, has been implicated in various aspects of human health and disease, including cancer. Previous studies have identified elevated serum ferritin (SF) levels in several ca…
View article: Table S3 - Bias in SF testing from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort
Table S3 - Bias in SF testing from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort Open
Comparison of MHS members who did or did not perform SF test, based on synthetic data of members who performed lab tests in 2016
View article: Table S1 - Sub-group Definition from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort
Table S1 - Sub-group Definition from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort Open
Detail on the different malignancies defining each sub-group used in the study
View article: Table S2 - Confounder ICD Codes from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort
Table S2 - Confounder ICD Codes from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort Open
ICD codes used in the study as confounding variables for the connection between SF and malignancy
View article: Table S5 - Sensitivity Analysis from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort
Table S5 - Sensitivity Analysis from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort Open
SF sensitivity analysis for the diagnosis of cancer
View article: Table S4 - Corrected p-values from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort
Table S4 - Corrected p-values from Strength in Numbers: Identifying a Significant Association between High Serum Ferritin Levels and Newly Diagnosed Malignancy in a Large Health Organization Cohort Open
FDR-Adjusted p values of subgroup analysis
View article: Real-world treatment patterns, biomarker testing, and clinical outcomes of metastatic non-small cell lung cancer patients in the immunotherapy era
Real-world treatment patterns, biomarker testing, and clinical outcomes of metastatic non-small cell lung cancer patients in the immunotherapy era Open
Background Treatment for first-line (1L) metastatic non-small cell cancer (mNSCLC) changed with the introduction of immunotherapy. We describe treatment utilization and clinical outcomes in a real-world mNSCLC cohort in a 2.7-million-membe…
View article: Healthcare resource utilization and associated cost in patients with metastatic non-small cell lung cancer treated in the immunotherapy era
Healthcare resource utilization and associated cost in patients with metastatic non-small cell lung cancer treated in the immunotherapy era Open
Background Treatment approach for metastatic non-small cell lung cancer (mNSCLC) has revolutionized in the recent decade with the introduction of immunotherapy and targeted medications in first-line (1L) therapy. We present real-world data…
View article: Benign transient hyperphosphatasemia in infants and children: a retrospective database study
Benign transient hyperphosphatasemia in infants and children: a retrospective database study Open
View article: Data from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma
Data from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma Open
The inability to forecast outcomes for malignant mesothelioma prevents clinicians from providing aggressive multimodality therapy to the most appropriate individuals who may benefit from such an approach. We investigated whether specific m…
View article: Supplementary Table 1 from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma
Supplementary Table 1 from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma Open
Supplementary Table 1 from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma
View article: Data from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma
Data from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma Open
The inability to forecast outcomes for malignant mesothelioma prevents clinicians from providing aggressive multimodality therapy to the most appropriate individuals who may benefit from such an approach. We investigated whether specific m…
View article: Supplementary Table 1 from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma
Supplementary Table 1 from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma Open
Supplementary Table 1 from hsa-miR-29c* Is Linked to the Prognosis of Malignant Pleural Mesothelioma
View article: Time-varying association of acute and post-acute COVID-19 with new-onset diabetes mellitus among hospitalized and non-hospitalized patients
Time-varying association of acute and post-acute COVID-19 with new-onset diabetes mellitus among hospitalized and non-hospitalized patients Open
Introduction Previous studies have shown disruption of glycometabolic control and new diabetes mellitus (DM) diagnosis among patients with COVID-19. It is still unclear how the association of COVID-19 and new-onset DM may be modified by di…
View article: Regional analgesia with or without general anaesthesia for breast cancer surgery: a network meta-analysis
Regional analgesia with or without general anaesthesia for breast cancer surgery: a network meta-analysis Open
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess whether the analgesic efficacy and safety differ according to the regional analgesia technique used in women undergoing breast c…
View article: Continuous Decline in Myocardial Infarction and Heart Failure Hospitalizations During the First 12 Months of the COVID-19 Pandemic in Israel
Continuous Decline in Myocardial Infarction and Heart Failure Hospitalizations During the First 12 Months of the COVID-19 Pandemic in Israel Open
Background A decline in cardiovascular hospitalizations was observed during the initial phases of the COVID-19 pandemic. We examine the continued effect of the pandemic on cardiovascular hospitalizations and the associated mortality rates …
View article: During evolution from the earliest tetrapoda, newly-recruited genes are increasingly paralogues of existing genes and distribute non-randomly among the chromosomes
During evolution from the earliest tetrapoda, newly-recruited genes are increasingly paralogues of existing genes and distribute non-randomly among the chromosomes Open
View article: The current distribution of recently-recruited genes among chromosomes appears increasingly non-random along the evolutionary series from the tetrapoda to the primata
The current distribution of recently-recruited genes among chromosomes appears increasingly non-random along the evolutionary series from the tetrapoda to the primata Open
Background: The present availability of full genome sequences of a broad range of animal species across the whole range of evolutionary history enables one to ask questions as to the distribution of genes across the chromosomes. Do newly r…
View article: <p>Combining Inpatient and Outpatient Data for Diagnosis of Non-Valvular Atrial Fibrillation Using Electronic Health Records: A Validation Study</p>
Combining Inpatient and Outpatient Data for Diagnosis of Non-Valvular Atrial Fibrillation Using Electronic Health Records: A Validation Study Open
In this study, involving a comprehensive data collection from inpatient and outpatient sources, incorporating outpatient data with inpatient data improved the diagnosis of non-valvular AF compared to inpatient data alone.
View article: M152. IS MEDICAL SERVICES UTILISATION A MODERATING FACTOR OF EARLY EXCESS MORTALITY IN PATIENTS WITH SCHIZOPHRENIA
M152. IS MEDICAL SERVICES UTILISATION A MODERATING FACTOR OF EARLY EXCESS MORTALITY IN PATIENTS WITH SCHIZOPHRENIA Open
Background Unlike the general population, patients with schizophrenia have an excess of chronic physical morbidities such as diabetes, cardiovascular and respiratory disorders. In addition, they do no gain from primary and secondary medica…
View article: Adherence to antidepressant medications is associated with reduced premature mortality in patients with cancer: A nationwide cohort study
Adherence to antidepressant medications is associated with reduced premature mortality in patients with cancer: A nationwide cohort study Open
The present study is the first to demonstrate that higher adherence to AD is associated with a decrease of all-cause mortality in a large nationwide cohort of cancer patients. Our data add to the pressing need to encourage adherence to AD …
View article: F113. LONG-TERM PHYSICAL HEALTH AND MORTALITY OUTCOMES OF PATIENTS WITH SCHIZOPHRENIA WITH CLOZAPINE AUGMENTATION WITH ANTI-PSYCHOTIC DRUGS
F113. LONG-TERM PHYSICAL HEALTH AND MORTALITY OUTCOMES OF PATIENTS WITH SCHIZOPHRENIA WITH CLOZAPINE AUGMENTATION WITH ANTI-PSYCHOTIC DRUGS Open
About a third of schizophrenia patients would not have sufficient clinical response to antipsychotic treatment. The only drug approved for this population is clozapine, yet worldwide reports suggest underuse of clozapine and significant de…
View article: Pre- and within hospitalization risk factors for readmission of older adults
Pre- and within hospitalization risk factors for readmission of older adults Open
The International Journal of Integrated Care (IJIC) is an online, open-access, peer-reviewed scientific journal that publishes original articles in the field of integrated care on a continuous basis.IJIC has an Impact Factor of 5.120 (2020…
View article: A prospective observational study of the change in regional cerebral oxygen saturation during cesarean delivery in women receiving phenylephrine prophylaxis for spinal hypotension
A prospective observational study of the change in regional cerebral oxygen saturation during cesarean delivery in women receiving phenylephrine prophylaxis for spinal hypotension Open
View article: Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality
Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality Open
Among obese patients in a large integrated health fund in Israel, bariatric surgery using laparoscopic banding, gastric bypass, or laparoscopic sleeve gastrectomy, compared with usual care nonsurgical obesity management, was associated wit…
View article: P1086Creating a prediction model to identify patients at high risk of undetected non-valvular atrial fibrillation
P1086Creating a prediction model to identify patients at high risk of undetected non-valvular atrial fibrillation Open
View article: Low adherence to antidepressants is associated with increased mortality in Parkinson disease patients
Low adherence to antidepressants is associated with increased mortality in Parkinson disease patients Open
Our findings suggest that poor adherence to AD is associated with increased all-cause mortality in people with PD. Given the high prevalence of depression and AD effectiveness, efforts to promote adherence should be prioritized in clinical…
View article: P721 A switch in the prevalence ratio of Crohn's disease vs. ulcerative colitis in Israel between 2003 and 2015 – a report from the epi-IIRN group
P721 A switch in the prevalence ratio of Crohn's disease vs. ulcerative colitis in Israel between 2003 and 2015 – a report from the epi-IIRN group Open
Background: Crohn's disease (CD) has been considered a condition limited mostly to westernized countries, while ulcerative colitis (UC) may be more common in some developing countries. We aimed to utilize data from all four Israeli …
View article: Association Between Achieved Low-Density Lipoprotein Levels and Major Adverse Cardiac Events in Patients With Stable Ischemic Heart Disease Taking Statin Treatment
Association Between Achieved Low-Density Lipoprotein Levels and Major Adverse Cardiac Events in Patients With Stable Ischemic Heart Disease Taking Statin Treatment Open
Patients with LDL-C levels of 70 to 100 mg/dL taking statins had lower risk of adverse cardiac outcomes compared with those with LDL-C levels between 100 and 130 mg/dL, but no additional benefit was gained by achieving LDL-C of 70 mg/dL or…