Mubarak Patel
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View article: Exploring decision-making in home care nursing: a commentary
Exploring decision-making in home care nursing: a commentary Open
View article: Reduced duration adjuvant trastuzumab in the treatment of patients with HER2-positive breast cancer: a meta-analysis of randomised controlled non-inferiority trials including IPD data
Reduced duration adjuvant trastuzumab in the treatment of patients with HER2-positive breast cancer: a meta-analysis of randomised controlled non-inferiority trials including IPD data Open
Objectives Adjuvant trastuzumab in combination with chemotherapy has significantly improved survival in patients with HER2-positive early breast cancer but, since introduction in 2005, the 12 months duration has been questioned and trials …
View article: When Evidence Falls Short—Belzutifan for Treating Tumours Associated with von Hippel-Lindau Disease: An External Assessment Group Perspective on a NICE Single Technology Appraisal
When Evidence Falls Short—Belzutifan for Treating Tumours Associated with von Hippel-Lindau Disease: An External Assessment Group Perspective on a NICE Single Technology Appraisal Open
View article: Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation
Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation Open
Background Lung cancer is one of the most common types of cancer and the leading cause of cancer death in the United Kingdom. Artificial intelligence-based software has been developed to reduce the number of missed or misdiagnosed lung nod…
View article: Effectiveness and Cost-Effectiveness of Empathic Healthcare: A Systematic Review and Meta-analysis
Effectiveness and Cost-Effectiveness of Empathic Healthcare: A Systematic Review and Meta-analysis Open
View article: Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling
Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling Open
Background Hybrid closed-loop systems are a new class of technology to manage type 1 diabetes mellitus. The system includes a combination of real-time continuous glucose monitoring from a continuous glucose monitoring device and a control …
View article: Ethnic-Specific Threshold Analysis and BMI and Waist Circumference Cutoffs for Cardiovascular Disease and Subjective Wellbeing: Results using Data from the UK Biobank
Ethnic-Specific Threshold Analysis and BMI and Waist Circumference Cutoffs for Cardiovascular Disease and Subjective Wellbeing: Results using Data from the UK Biobank Open
Objectives We aimed to identify ethnicity-specific BMI and waist circumference cutoffs for cardiovascular disease (CVD) and to define optimal thresholds for CVD risk and subjective wellbeing (SWB) through predictive modelling, to inform pr…
View article: Software using artificial intelligence for nodule and cancer detection in CT lung cancer screening: systematic review of test accuracy studies
Software using artificial intelligence for nodule and cancer detection in CT lung cancer screening: systematic review of test accuracy studies Open
Objectives To examine the accuracy and impact of artificial intelligence (AI) software assistance in lung cancer screening using CT. Methods A systematic review of CE-marked, AI-based software for automated detection and analysis of nodule…
View article: Artificial intelligence software for analysing chest X-ray images to identify suspected lung cancer: an evidence synthesis early value assessment
Artificial intelligence software for analysing chest X-ray images to identify suspected lung cancer: an evidence synthesis early value assessment Open
Background Lung cancer is one of the most common types of cancer in the United Kingdom. It is often diagnosed late. The 5-year survival rate for lung cancer is below 10%. Early diagnosis may improve survival. Software that has an artificia…
View article: Bayesian Hierarchical Modelling for Histology-Independent Time-to-Event Outcomes in the NICE Single Technology Appraisal of Pembrolizumab for Solid Tumours with MSI-H/dMMR: External Assessment Group Perspective
Bayesian Hierarchical Modelling for Histology-Independent Time-to-Event Outcomes in the NICE Single Technology Appraisal of Pembrolizumab for Solid Tumours with MSI-H/dMMR: External Assessment Group Perspective Open
View article: Factors associated with cardiovascular disease: A comparative study of the UK Asian diaspora and residents of India
Factors associated with cardiovascular disease: A comparative study of the UK Asian diaspora and residents of India Open
Introduction The aim of this paper is to investigate what factors are associated to cardiovascular disease and what differences exists between Asians living in the UK (from the English Longitudinal Study of Ageing) and the Asians living in…
View article: Translating potential improvement in the precision and accuracy of lung nodule measurements on computed tomography scans by software derived from artificial intelligence into impact on clinical practice—a simulation study
Translating potential improvement in the precision and accuracy of lung nodule measurements on computed tomography scans by software derived from artificial intelligence into impact on clinical practice—a simulation study Open
Objectives Accurate measurement of lung nodules is pivotal to lung cancer detection and management. Nodule size forms the main basis of risk categorization in existing guidelines. However, measurements can be highly variable between manual…
View article: Commentary: Exploring predictors of perceived stress: a cross-sectional study among nursing students during their clinical practice
Commentary: Exploring predictors of perceived stress: a cross-sectional study among nursing students during their clinical practice Open
View article: Risk factors for newly-developed cardiovascular disease and quality of life during the COVID − 19 pandemic: an analysis of the English longitudinal study of ageing
Risk factors for newly-developed cardiovascular disease and quality of life during the COVID − 19 pandemic: an analysis of the English longitudinal study of ageing Open
Introduction The COVID-19 pandemic had a wide range of effects on the English population, including on health and quality of life due to the subsequent lockdown restrictions set. Aims To investigate longitudinal changes in developing cardi…
View article: Commentary: Gluteal muscle and subcutaneous tissue thicknesses in adults: a systematic review and meta-analysis
Commentary: Gluteal muscle and subcutaneous tissue thicknesses in adults: a systematic review and meta-analysis Open
View article: Risk factors for newly-developed cardiovascular disease and quality of life during the COVID -19 pandemic: an analysis of the English Longitudinal Study of Ageing
Risk factors for newly-developed cardiovascular disease and quality of life during the COVID -19 pandemic: an analysis of the English Longitudinal Study of Ageing Open
Introduction The COVID-19 pandemic had a wide range of effects on the English population, including on health and quality of life due to the subsequent lockdown restrictions set. Aims To investigate longitudinal changes in developing cardi…
View article: Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review
Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review Open
View article: Impact of quality of life in developing cardiovascular disease later in life: Graphical chain model of the English Longitudinal Study of Ageing (ELSA)
Impact of quality of life in developing cardiovascular disease later in life: Graphical chain model of the English Longitudinal Study of Ageing (ELSA) Open
Events related to cardiovascular disease only affected quality of life in later life up to 4 years. Factors such as age, depression, perceived position on social ladder, and high levels of physical activity affected quality of life through…
View article: Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review
Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review Open
Background Cardiovascular disease is the leading cause of death worldwide, with significantly worse mortality-related outcomes in ethnic minorities in developed countries. A systematic literature review and meta-analysis of observational s…
View article: Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol
Ethnic differences between South Asians and white Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review protocol Open
Introduction Cardiovascular disease (CVD) is the leading cause of death worldwide, with significantly worse CVD outcomes in ethnic minorities in developed countries, especially South Asians, compared with the prevailing white ethnic group.…
View article: Additional file 1 of Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review
Additional file 1 of Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review Open
Additional file 1. a. PRISMA 2020 Checklist. b. PRISMA 2020 abstract checklist.
View article: Impact of Quality of Life in Developing Cardiovascular Disease Later in Life: Graphical Chain Model of the English Longitudinal Study of Ageing (ELSA)
Impact of Quality of Life in Developing Cardiovascular Disease Later in Life: Graphical Chain Model of the English Longitudinal Study of Ageing (ELSA) Open
View article: Prevalence and determinants of depression up to 5 years after colorectal cancer surgery: results from the ColoREctal Wellbeing (CREW) study
Prevalence and determinants of depression up to 5 years after colorectal cancer surgery: results from the ColoREctal Wellbeing (CREW) study Open
Aim Depression experienced by people with colorectal cancer (CRC) is an important clinical problem affecting quality of life. Recognition of depression at key points in the pathway enables timely referral to support. This study aimed to ex…
View article: Rationale and design of a cross-sectional study to investigate and describe the chronotype of patients with type 2 diabetes and the effect on glycaemic control: the CODEC study
Rationale and design of a cross-sectional study to investigate and describe the chronotype of patients with type 2 diabetes and the effect on glycaemic control: the CODEC study Open
Introduction A person’s chronotype is their entrained preference for sleep time within the 24 hours clock. It is described by the well-known concept of the ‘lark’ (early riser) and ‘owl’ (late sleeper). Evidence suggests that the ‘owl’ is …
View article: Supportive care needs of patients following treatment for colorectal cancer: risk factors for unmet needs and the association between unmet needs and health-related quality of life—results from the ColoREctal Wellbeing (CREW) study
Supportive care needs of patients following treatment for colorectal cancer: risk factors for unmet needs and the association between unmet needs and health-related quality of life—results from the ColoREctal Wellbeing (CREW) study Open
Purpose To investigate unmet needs of patients with colorectal cancer (CRC) at the end of treatment and whether unmet needs improve over time. Identify predictors of need following treatment and whether unmet need is associated with worse …
View article: Comorbidities are associated with poorer quality of life and functioning and worse symptoms in the 5 years following colorectal cancer surgery: Results from the ColoREctal Well‐being (CREW) cohort study
Comorbidities are associated with poorer quality of life and functioning and worse symptoms in the 5 years following colorectal cancer surgery: Results from the ColoREctal Well‐being (CREW) cohort study Open
Objective More people are living with the consequences of cancer and comorbidity. We describe frequencies of comorbidities in a colorectal cancer cohort and associations with health and well‐being outcomes up to 5 years following surgery. …