Talat Nasim
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View article: Regulation of TGF-β and BMP Signaling by Natural Triterpene Compounds in Pulmonary Arterial Hypertension (PAH)
Regulation of TGF-β and BMP Signaling by Natural Triterpene Compounds in Pulmonary Arterial Hypertension (PAH) Open
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder caused by right heart failure leading to premature death. The TGFBR2 and BMPR-II receptors, which are members of the TGF-β receptor family, are considered promi…
View article: Anti-Inflammatory, Analgesic, and Anxiolytic Effects of Crude Extracts and Isolated Bioactive Fractional Compounds from Pouzolzia sanguinea
Anti-Inflammatory, Analgesic, and Anxiolytic Effects of Crude Extracts and Isolated Bioactive Fractional Compounds from Pouzolzia sanguinea Open
Pharmacological relevance: Ethnic people residing in the Chittagong Hill Tracts (CHTs) of Bangladesh use Pouzolzia sanguinea to alleviate flatulence, for menstruation, inflammation, insomnia, and analgesia. However, there is no scientific …
View article: The Effects of Antipsychotic Drugs and Non-Pharmacological Therapies on Schizophrenia
The Effects of Antipsychotic Drugs and Non-Pharmacological Therapies on Schizophrenia Open
Schizophrenia is a severe and complex psychological disorder characterised by psychosis, affecting approximately 20 million people worldwide, with its prevalence on the rise. It is hypothesised to arise from a multifactorial aetiology invo…
View article: Therapeutic Resolution of Pulmonary Arterial Hypertension (PAH) Using Natural Products
Therapeutic Resolution of Pulmonary Arterial Hypertension (PAH) Using Natural Products Open
Pulmonary arterial hypertension (PAH) is a progressive and rare condition characterised by the occlusion of pulmonary arterioles, with clinical manifestations resulting from the cross-sectional area reduction of the small pulmonary arterie…
View article: The Prospect and Challenges of Repurposing Established Drugs in Pulmonary Arterial Hypertension
The Prospect and Challenges of Repurposing Established Drugs in Pulmonary Arterial Hypertension Open
Pulmonary arterial hypertension (PAH) is a progressive disorder caused by the narrowing of small blood vessels in the lungs, which, in the absence of therapies, leads to right heart failure and premature death. No cure for this devastating…
View article: Supplementary Figure 1 from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing
Supplementary Figure 1 from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing Open
PDF file - 183K
View article: Data from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing
Data from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing Open
The c-jun gene regulates cellular proliferation and apoptosis via direct regulation of cellular gene expression. Alternative splicing of pre-mRNA increases the diversity of protein functions, and alternate splicing events occur in t…
View article: Data from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing
Data from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing Open
The c-jun gene regulates cellular proliferation and apoptosis via direct regulation of cellular gene expression. Alternative splicing of pre-mRNA increases the diversity of protein functions, and alternate splicing events occur in t…
View article: Supplementary Figure 1 from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing
Supplementary Figure 1 from Mammary Gland Selective Excision of <i>c-Jun</i> Identifies Its Role in mRNA Splicing Open
PDF file - 183K
View article: Development and Optimisation of Inhalable EGCG Nano-Liposomes as a Potential Treatment for Pulmonary Arterial Hypertension by Implementation of the Design of Experiments Approach
Development and Optimisation of Inhalable EGCG Nano-Liposomes as a Potential Treatment for Pulmonary Arterial Hypertension by Implementation of the Design of Experiments Approach Open
Epigallocatechin gallate (EGCG), the main ingredient in green tea, holds promise as a potential treatment for pulmonary arterial hypertension (PAH). However, EGCG has many drawbacks, including stability issues, low bioavailability, and a s…
View article: 186 Effects of an established drug on smad signalling pathway in the rat model of monocrotaline pulmonary hypertension
186 Effects of an established drug on smad signalling pathway in the rat model of monocrotaline pulmonary hypertension Open
Introduction Pulmonary arterial hypertension (PAH) is a complex multifactorial disease with both genetic and environmental dynamics contributing to disease progression that characterized by unbalanced proliferation and apoptosis of pulmona…
View article: Targeting the TGF-β signaling pathway for resolution of pulmonary arterial hypertension
Targeting the TGF-β signaling pathway for resolution of pulmonary arterial hypertension Open
View article: COVID-19: A natural phenomena or laboratory-based origin?
COVID-19: A natural phenomena or laboratory-based origin? Open
The novel coronavirus, otherwise known as COVID-19 has fast become a major health concern. The current pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV‐ 2) is the third coronavirus outbreak, following severe acut…
View article: Aminoglycoside-mediated promotion of translation readthrough occurs through a non-stochastic mechanism that competes with translation termination
Aminoglycoside-mediated promotion of translation readthrough occurs through a non-stochastic mechanism that competes with translation termination Open
Attempts have been made to treat nonsense-associated genetic disorders by chemical agents and hence an improved mechanistic insight into the decoding of readthrough signals is essential for the identification and characterisation of factor…
View article: AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors Open
Alternative splicing of pre-mRNAs significantly contributes to the complexity of gene expression in higher organisms, but the regulation of the splice site selection remains incompletely understood. We have previously demonstrated that a c…
View article: Corrigendum to “Data for proteomic analysis of murine cardiomyocytic HL-1 cells treated with siRNA against tissue factor” [Data Brief 3 (2015) 117–119]
Corrigendum to “Data for proteomic analysis of murine cardiomyocytic HL-1 cells treated with siRNA against tissue factor” [Data Brief 3 (2015) 117–119] Open
View article: Data for proteomic analysis of murine cardiomyocytic HL-1 cells treated with siRNA against tissue factor
Data for proteomic analysis of murine cardiomyocytic HL-1 cells treated with siRNA against tissue factor Open
View article: Proteomics of tissue factor silencing in cardiomyocytic cells reveals a new role for this coagulation factor in splicing machinery control
Proteomics of tissue factor silencing in cardiomyocytic cells reveals a new role for this coagulation factor in splicing machinery control Open