Mudatsir Mudatsir
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View article: Effect of colchicine administration on interleukin-1β and nitric oxide expression at the early stage of atherosclerosis in atherosclerosis Wistar rat model
Effect of colchicine administration on interleukin-1β and nitric oxide expression at the early stage of atherosclerosis in atherosclerosis Wistar rat model Open
In the early development of atherosclerosis, colchicine was significantly more effective than atorvastatin in increasing the NO levels and demonstrated a comparable ability to reduce the IL-1β levels. These findings suggest that colchicine…
View article: Relationship between the Left Atrial Volume Index and Left Ventricular Geometry and the Incidence of Atrial Fibrillation in Hypertensive Patients with Cardiovascular Complications
Relationship between the Left Atrial Volume Index and Left Ventricular Geometry and the Incidence of Atrial Fibrillation in Hypertensive Patients with Cardiovascular Complications Open
This study aimed to evaluate the relationships of the left atrial volume index (LAVI) and left ventricular geometry with the incidence of AF in hypertensive patients with cardiovascular complications such as heart failure or coronary arter…
View article: Acceptance for a booster dose of COVID-19 vaccine in Indonesia: A follow-up study
Acceptance for a booster dose of COVID-19 vaccine in Indonesia: A follow-up study Open
The coronavirus disease 2019 (COVID-19) vaccination program in Indonesia has been implemented as a key strategy to mitigate the spread of the virus within communities. The success of this program depends on public acceptance of COVID-19 va…
View article: Ascorbic acid and calcitriol as alternative preventive strategies for myocardial damage in type 2 diabetes mellitus: an in vivo study using diabetic and atherosclerotic rat models
Ascorbic acid and calcitriol as alternative preventive strategies for myocardial damage in type 2 diabetes mellitus: an in vivo study using diabetic and atherosclerotic rat models Open
BACKGROUND: Type 2 diabetes mellitus can increase the production of reactive oxygen species (ROS) and genetic transcription factors, such as nuclear factor kappa beta (NF-κB). These phenomena may enhance the progression of atherosclerosis.…
View article: Comparative study of anti-SARS-CoV-2 receptor-binding domain total antibody titer before and after heterologous booster with mRNA-based COVID-19 vaccine
Comparative study of anti-SARS-CoV-2 receptor-binding domain total antibody titer before and after heterologous booster with mRNA-based COVID-19 vaccine Open
The waning immunity following the COVID-19 vaccination become a significant concern and the immunological dynamics of vaccine-induced antibodies after vaccination need to be explored. The aim of this study was to compare anti-SARS-CoV-2 re…
View article: Determinants of Implementation of Dental Health Promotion in Elementary School Children: Study on Teachers and Parents
Determinants of Implementation of Dental Health Promotion in Elementary School Children: Study on Teachers and Parents Open
Dental and oral health has an important role and impact on general health conditions and child development. One of the efforts to prevent dental disease early in children can be done through promotion and education about children 's dental…
View article: Uric Acid-HDL Ratio as Predictor of Major Cardiovascular Events in Very High Cardiovascular Risk Patients Treated with High-Intensity Statin Therapy
Uric Acid-HDL Ratio as Predictor of Major Cardiovascular Events in Very High Cardiovascular Risk Patients Treated with High-Intensity Statin Therapy Open
Introduction: Uric acid levels are positively correlated with cardiovascular disease. High Density Lipoprotein (HDL) cholesterol plays a role in suppressing blood oxidation reactions and protecting vascular endothelial cells. The combinati…
View article: Inhibitory Effects of Linot, Yellow, and Black Honey Extracts on Carbapenem-Resistant Klebsiella pneumoniae and Escherichia coli in Wound Infections
Inhibitory Effects of Linot, Yellow, and Black Honey Extracts on Carbapenem-Resistant Klebsiella pneumoniae and Escherichia coli in Wound Infections Open
Honey is known to have potential as an alternative treatment for wound infections caused by bacteria. This study aimed to evaluate honey's antimicrobial activity against Carbapenem-resistant Klebsiella pneumoniae and Escherichia coli in vi…
View article: Application Of Video-Assisted Problem Based Learning Models To Improve Student Learning Outcomes On Virus Material
Application Of Video-Assisted Problem Based Learning Models To Improve Student Learning Outcomes On Virus Material Open
Learning in the era of globalization directs teachers to use learning models that are adapted to existing technological media. Based on the data obtained, there is still a learning process that has not maximized the use of technological me…
View article: Determinants of Nursing Risk Diagnosis of Decrease in Heart Rate in Patients with Cardiovascular Disease at the Aceh Provincial General Hospital
Determinants of Nursing Risk Diagnosis of Decrease in Heart Rate in Patients with Cardiovascular Disease at the Aceh Provincial General Hospital Open
Decreased cardiac output is a primary nursing diagnosis for patients with cardiovascular disease (CVD), which is a life-threatening condition requiring immediate consideration and action. This study aims to identify the determinants of dec…
View article: Risk factors of pulmonary tuberculosis in Indonesia: A case-control study in a high disease prevalence region
Risk factors of pulmonary tuberculosis in Indonesia: A case-control study in a high disease prevalence region Open
Tuberculosis (TB) remains one of the most widespread infectious diseases in the world, with high mortality and morbidity rates, contributing to a significant disease burden, particularly in developing countries. The aim of this study was t…
View article: The Effect of Using Papain Enzyme on Quality Analysis of Buffalo Meat Jerky
The Effect of Using Papain Enzyme on Quality Analysis of Buffalo Meat Jerky Open
One type of meat preservation is making jerky by using various types of seasoning ingredients from nature. Meat jerky is very popular with people in the market. Most jerky currently on the market is generally made from beef, and very littl…
View article: Therapeutic activities of honey in wound care: a narrative review
Therapeutic activities of honey in wound care: a narrative review Open
Honey is a natural product that has a sweet taste and rich in phenolic compounds. Honey also contains some other compounds such as enzymes, amino acids, proteins, sugars, carbohydrates, lipids, vitamins and minerals. Honey has a potential …
View article: Hemostatic and liver function parameters as COVID-19 severity markers
Hemostatic and liver function parameters as COVID-19 severity markers Open
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a disease newly discovered in December 2019 which affects coagulation cascade and liver functions. The aim of this study was to…
View article: ANALYSIS OF THE PROJECT BASED LEARNING LEARNING MODEL BY UTILIZING YOUTUBE MEDIA TO IMPROVE STUDENTS' SPEECH SKILLS AT SMP NEGERI 3 MERAUKE
ANALYSIS OF THE PROJECT BASED LEARNING LEARNING MODEL BY UTILIZING YOUTUBE MEDIA TO IMPROVE STUDENTS' SPEECH SKILLS AT SMP NEGERI 3 MERAUKE Open
This research aims to analyze the project-based learning model (PjBL) using YouTube video media in student speech learning. The research subjects were carried out on class IX students in the odd semester of 2023. The research was carried o…
View article: Qualitative Analysis of Sanitation Management in Residential Area around Gampong Jawa Landfill in 2021 Based on Fly Distribution Pattern
Qualitative Analysis of Sanitation Management in Residential Area around Gampong Jawa Landfill in 2021 Based on Fly Distribution Pattern Open
Aim: Residents are concerned about the presence of flies, especially in areas near landfills, so it is important to study the distribution patterns of fly communities and community responses to the presence of flies. This study focuses on …
View article: Determination of Total Phenolic Content and Total Flavonoid Content of Nutmeg Flesh (Myristica Fragrans Houtt) Ethanol Extract from South Aceh Province
Determination of Total Phenolic Content and Total Flavonoid Content of Nutmeg Flesh (Myristica Fragrans Houtt) Ethanol Extract from South Aceh Province Open
The nutmeg plant (Myristica fragrans Houtt) is often used as a medicinal ingredient and has medicinal efficacy. Nutmeg samples were obtained from South Aceh district, which is the main commodity obtained in the area. This study aims to mea…
View article: Quantity of antibiotic use and its association with clinical outcomes in COVID-19 patients: A snapshot from a provincial referral hospital in Indonesia
Quantity of antibiotic use and its association with clinical outcomes in COVID-19 patients: A snapshot from a provincial referral hospital in Indonesia Open
Irrational antibiotic use in Indonesia is considered high, yet there are still lacks reliable information regarding the issue. The quantity of antibiotic use studies, in particular during coronavirus disease 2019 (COVID-19) pandemic, was n…
View article: The Effects of Lumbricus rubellus Extract on Staphylococcus aureus Colonization and IL-31 Levels in Children with Atopic Dermatitis
The Effects of Lumbricus rubellus Extract on Staphylococcus aureus Colonization and IL-31 Levels in Children with Atopic Dermatitis Open
Background and Objectives: The ineffective combination of corticosteroids and antibiotics in treating some atopic dermatitis (AD) cases has been concerning. The skin barrier defects in AD ease the colonization of Staphylococcus aureus (S. …
View article: Characteristic and bioactivities value of Nypa fruticans from coastal area in West Aceh District, Indonesia as a candidate antidiabetic agent
Characteristic and bioactivities value of Nypa fruticans from coastal area in West Aceh District, Indonesia as a candidate antidiabetic agent Open
Fitri Y, Yusni Y, Suryadi T, Mudatsir M. 2023. Characteristic and bioactivities value of Nypa fruticans from coastal area in West Aceh District, Indonesia as a candidate antidiabetic agent. Biodiversitas 24: 5260-5269. Nypa fruticans Wurmb…
View article: Antibacterial and anti-inflammatory activities of Nothopanax scutellarium, Moringa oleifera and Piper betle extracts on staphylococcal mastitis animal model
Antibacterial and anti-inflammatory activities of Nothopanax scutellarium, Moringa oleifera and Piper betle extracts on staphylococcal mastitis animal model Open
Inappropriate and prolonged administration of antibiotics in mastitis could cause antibiotic resistance and herbal treatment might could be one alternative treatment. Nothopanax scutellarium, Moringa oleifera, and Piper betle are medicinal…
View article: Risk factors of MDR-TB and impacts of COVID-19 pandemic on escalating of MDR-TB incidence in lower-middle-income countries: A scoping review
Risk factors of MDR-TB and impacts of COVID-19 pandemic on escalating of MDR-TB incidence in lower-middle-income countries: A scoping review Open
The coronavirus disease 2019 (COVID-19) pandemic is affecting tuberculosis (TB) treatment in many ways that might lead to increasing the prevalence of multi-drugs-resistance tuberculosis (MDR-TB), especially in lower-middle-income-countrie…
View article: Application of the Video-Assisted Problem Based Learning Model to Increase Student Learning Motivation in Virus Material
Application of the Video-Assisted Problem Based Learning Model to Increase Student Learning Motivation in Virus Material Open
Learning activities are strongly empowered by the use of appropriate teaching models and media. If learning activities are not well designed and correct, it will affect learning outcomes. motivation are indicators in improving the quality …
View article: Relationship between metalloproteinase-9 (MMP-9) expression and clinicopathology in colorectal cancer: a cross-sectional study
Relationship between metalloproteinase-9 (MMP-9) expression and clinicopathology in colorectal cancer: a cross-sectional study Open
Introduction: According to the WHO’s GLOBOCAN database, ~1,931,590 new colorectal cancer (CRC) cases and 915,607 CRC-related deaths occurred in 2020. The incidence of CRC in Indonesia is 8.6%, making it the fourth most common cancer. With …
View article: Probing antibacterial drugs for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 targeting UDP-N-acetylglucosamine 1-carboxyltransferase
Probing antibacterial drugs for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 targeting UDP-N-acetylglucosamine 1-carboxyltransferase Open
Fusobacterium nucleatum is a Gram-negative anaerobic bacteria that is commonly found in oral cavities and is associated with connective tissue destruction in periodontitis. UDP-N-acetylglucosamine 1-carboxyltransferase with enzyme commissi…
View article: Willingness-to-pay for a hypothetical Ebola vaccine in Indonesia: A cross-sectional study in Aceh
Willingness-to-pay for a hypothetical Ebola vaccine in Indonesia: A cross-sectional study in Aceh Open
Background: Some Ebola vaccines have been developed and tested in phase III clinical trials. However, assessment of whether public have willingness to purchase or not, especially in unaffected areas, is lacking. The aim of this study was t…
View article: DIFFERENCES IN LEVELS OF KNOWLEDGE AND BEHAVIOR OF COVID-19 PREVENTION BETWEEN MEDICAL PERSONNEL AT CUT NYAK DHIEN GENERAL HOSPITAL AND HARAPAN SEHAT HOSPITAL
DIFFERENCES IN LEVELS OF KNOWLEDGE AND BEHAVIOR OF COVID-19 PREVENTION BETWEEN MEDICAL PERSONNEL AT CUT NYAK DHIEN GENERAL HOSPITAL AND HARAPAN SEHAT HOSPITAL Open
The role of health workers is the most important part in tackling the Covid-19 pandemic. All coping policies affect the services provided in hospitals so that they have a negative impact on the health care sector. To reduce the transmissio…
View article: Waning anti-SARS-CoV-2 receptor-binding domain total antibody in CoronaVac-vaccinated individuals in Indonesia
Waning anti-SARS-CoV-2 receptor-binding domain total antibody in CoronaVac-vaccinated individuals in Indonesia Open
Background: The decrease of immunity acquired from COVID-19 vaccines is a potential cause of breakthrough infection. Understanding the dynamics of immune responses of vaccine-induced antibodies post-vaccination is important. This study aim…