Mudsser Azam
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View article: Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions
Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions Open
Visceral leishmaniasis (VL) is a significant global health concern, causing considerable morbidity and mortality. The prevalence of VL is influenced by environmental conditions and limited access to healthcare services. Accurate diagnostic…
View article: Neuro-leishmaniasis with cauda equina syndrome and cranial nerve palsy: a rare manifestation of recurrent atypical visceral leishmaniasis
Neuro-leishmaniasis with cauda equina syndrome and cranial nerve palsy: a rare manifestation of recurrent atypical visceral leishmaniasis Open
Unlike previously reported cases with both systemic and neurological symptoms, our patient predominantly presented with neurological manifestations, making this a unique and novel presentation of VL. This case highlights diagnostic challen…
View article: Neuro-leishmaniasis with Cauda Equina Syndrome and Cranial Nerve Palsy: A Rare Manifestation of Recurrent Atypical Visceral Leishmaniasis
Neuro-leishmaniasis with Cauda Equina Syndrome and Cranial Nerve Palsy: A Rare Manifestation of Recurrent Atypical Visceral Leishmaniasis Open
Background Visceral leishmaniasis (VL) is a neglected tropical disease primarily affecting Brazil, East Africa, and India, with India accounting for 18% of the global burden. While VL typically presents with systemic symptoms like fever, w…
View article: Assessment of High-Resolution Melting Curve Analysis for Leishmania spp. Detection in Different Clinical Manifestations of Leishmaniasis in India
Assessment of High-Resolution Melting Curve Analysis for Leishmania spp. Detection in Different Clinical Manifestations of Leishmaniasis in India Open
The accurate diagnosis and identification of Leishmania species are crucial for the therapeutic selection and effective treatment of leishmaniasis. This study aims to develop and evaluate the use of high-resolution melting curve analysis (…
View article: Sustainable One-Pot Synthesized Nanostructured Polybenzoxazine Films/Coatings from Bio-Derived Precursors (Cardanol and Furfurylamine)
Sustainable One-Pot Synthesized Nanostructured Polybenzoxazine Films/Coatings from Bio-Derived Precursors (Cardanol and Furfurylamine) Open
View article: Review of: "Inhibiting Efflux Pumps and Resistance Mechanisms: A Mini Review"
Review of: "Inhibiting Efflux Pumps and Resistance Mechanisms: A Mini Review" Open
Efflux Pumps and Resistance Mechanisms: A Mini Review" underscores the topic of the day.Undoubtedly, antibiotic resistance is a major concern in the clinical fraternity.Tackling antibiotic resistance is of utmost importance.However, the ma…
View article: Unusual Observations in Leishmaniasis—An Overview
Unusual Observations in Leishmaniasis—An Overview Open
Leishmaniasis significantly affects the population of the tropics and subtropics. Clinical features and infective species of Leishmania are the primary factors driving the direction of diagnosis. The rise in incidences of atypical presenta…
View article: Phenolic lipid derived coordination polymer nanocomposites: Synthesis, characterization and surface protective coating applications
Phenolic lipid derived coordination polymer nanocomposites: Synthesis, characterization and surface protective coating applications Open
Fabrication of renewable-resource (Cardanol, Col) based nanocomposite films/coatings has opened up a new path in the development of a sustainable and environment-friendly polymeric material with prodigious attention. In the present work, C…
View article: Development of Two-Tube Loop-Mediated Isothermal Amplification Assay for Differential Diagnosis of Plasmodium falciparum and Plasmodium vivax and Its Comparison with Loopamp™ Malaria
Development of Two-Tube Loop-Mediated Isothermal Amplification Assay for Differential Diagnosis of Plasmodium falciparum and Plasmodium vivax and Its Comparison with Loopamp™ Malaria Open
To strengthen malaria surveillance, field-appropriate diagnostics requiring limited technical resources are of critical significance. Loop-mediated isothermal amplification (LAMP) based malaria diagnostic assays are potential point-of-care…
View article: Emergence of a Novel Reassortant H5N3 Avian Influenza Virus in Korean Mallard Ducks in 2018
Emergence of a Novel Reassortant H5N3 Avian Influenza Virus in Korean Mallard Ducks in 2018 Open
Introduction: The avian influenza (AI) virus causes a highly contagious disease which is common in wild and domestic birds and sporadic in humans. Mutations and genetic reassortments among the 8 negative-sense RNA segments of…
View article: Colistin Resistance Among Multiple Sequence Types of Klebsiella pneumoniae Is Associated With Diverse Resistance Mechanisms: A Report From India
Colistin Resistance Among Multiple Sequence Types of Klebsiella pneumoniae Is Associated With Diverse Resistance Mechanisms: A Report From India Open
Background: The resistance to colistin and carbapenems in Klebsiella pneumoniae infections have been associated with increased morbidity and mortality worldwide. A retrospective observational study was conducted to determine the prevalence…
View article: Supplementary Material for: Emergence of a Novel Reassortant H5N3 Avian Influenza Virus in Korean Mallard Ducks in 2018
Supplementary Material for: Emergence of a Novel Reassortant H5N3 Avian Influenza Virus in Korean Mallard Ducks in 2018 Open
Introduction: The avian influenza (AI) virus causes a highly contagious disease which is common in wild and domestic birds and sporadic in humans. Mutations and genetic reassortments among the 8 negative-sense RNA segments of…
View article: Multiple variants of phoP/Q and pmrAB TCRS conferring colistin resistance in XDR/MDR clinical isolates of Klebsiella pneumoniae in India
Multiple variants of phoP/Q and pmrAB TCRS conferring colistin resistance in XDR/MDR clinical isolates of Klebsiella pneumoniae in India Open
Background: Several incidences worldwide have marked the emergence of colistin and carbapenem resistance in K. pneumoniae and increased morbidity and mortality associated with their infections. A retrospective observational study was condu…
View article: Pharmaceutical disposal facilitates the mobilization of resistance determinants among microbiota of polluted environment
Pharmaceutical disposal facilitates the mobilization of resistance determinants among microbiota of polluted environment Open
View article: Diagnostic Performance of Dengue Virus Envelope Domain III in Acute Dengue Infection
Diagnostic Performance of Dengue Virus Envelope Domain III in Acute Dengue Infection Open
Dengue, one of the most prevalent illnesses caused by dengue viruses that are members of the genus Flavivirus, is a significant global health problem. However, similar clinical symptoms and high antigenic homologies with other Flaviviruses…
View article: Synthesis and mechanistic studies of diketo acids and their bioisosteres as potential antibacterial agents
Synthesis and mechanistic studies of diketo acids and their bioisosteres as potential antibacterial agents Open
View article: Natural Product-Based 1,2,3-Triazole/Sulfonate Analogues as Potential Chemotherapeutic Agents for Bacterial Infections
Natural Product-Based 1,2,3-Triazole/Sulfonate Analogues as Potential Chemotherapeutic Agents for Bacterial Infections Open
Despite the vast availability of antibiotics, bacterial infections remain a leading cause of death worldwide. In an effort to enhance the armamentarium against resistant bacterial strains, 1,2,3-triazole (5a-x) and sulfonate (7a-…
View article: Study of pandrug and heavy metal resistance among E. coli from anthropogenically influenced Delhi stretch of river Yamuna
Study of pandrug and heavy metal resistance among E. coli from anthropogenically influenced Delhi stretch of river Yamuna Open
Escalating burden of antibiotic resistance that has reached new heights present a grave concern to mankind. As the problem is no longer confined to clinics, we hereby report identification of a pandrug resistant Escherichia coli isolate fr…
View article: CCDC 1516149: Experimental Crystal Structure Determination
CCDC 1516149: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1516147: Experimental Crystal Structure Determination
CCDC 1516147: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1516150: Experimental Crystal Structure Determination
CCDC 1516150: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1516148: Experimental Crystal Structure Determination
CCDC 1516148: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Perspective Insights into Disease Progression, Diagnostics, and Therapeutic Approaches in Alzheimer's Disease: A Judicious Update
Perspective Insights into Disease Progression, Diagnostics, and Therapeutic Approaches in Alzheimer's Disease: A Judicious Update Open
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive accumulation of β-amyloid fibrils and abnormal tau proteins in and outside of neurons. Representing a common form of dementia, aggravation of AD with…
View article: blaCTX-M-152, a Novel Variant of CTX-M-group-25, Identified in a Study Performed on the Prevalence of Multidrug Resistance among Natural Inhabitants of River Yamuna, India
blaCTX-M-152, a Novel Variant of CTX-M-group-25, Identified in a Study Performed on the Prevalence of Multidrug Resistance among Natural Inhabitants of River Yamuna, India Open
Natural environment influenced by anthropogenic activities creates selective pressure for acquisition and spread of resistance genes. In this study, we determined the prevalence of Extended Spectrum β-Lactamases producing gram negative bac…
View article: Analysis for the presence of determinants involved in the transport of mercury across bacterial membrane from polluted water bodies of India
Analysis for the presence of determinants involved in the transport of mercury across bacterial membrane from polluted water bodies of India Open
View article: Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants
Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants Open
Heavy metals, which have widespread environmental distribution and originate from natural and anthropogenic sources, are common environmental pollutants. In recent decades, their contamination has increased dramatically because of continuo…
View article: Plant abiotic stress: a prospective strategy of exploiting promoters as alternative to overcome the escalating burden
Plant abiotic stress: a prospective strategy of exploiting promoters as alternative to overcome the escalating burden Open
Plants being sessile are shaped by evolution to adapt themselves and tolerate various stresses, be it salinity stress, drought, high/low temperature in nature. They have evolved with every alternate strategy to tackle serious abiotic stres…