Explanipedia

Commentary: Healthy Eating Index-2020 and bowel habits: a cross-sectional analysis of NHANES Open

Mueez Waqar, Noor Un Nisa Irshad, Mohammed Hammad Jaber Amin · 2025

Endocrine and Biochemical Dysregulation in Beta-Thalassemia: Pathophysiology and Biomarkers Open

Muhammad Ahmad Khan, Mueez Waqar, Muhammad Tariq Masood Khan, Saba Noor, Maria Kamran , et al. · 2025

This study assessed endocrine dysfunction in 34 transfusion-dependent beta-thalassemia patients (mean age 17.35±2 years) from Pakistan, where disease burden is high (5,000–9,000 annual births). All patients had severe iron overload (mean f…

Minimal Hepatic Encephalopathy in Patients with Cirrhosis Using Psychometric Hepatic Encephalopathy Score Tests Open

Humaira Zakir, A. Khokar, Waqas Manzoor, Habiba Aman, Mueez Waqar , et al. · 2025

Minimal hepatic encephalopathy (MHE) is defined as changes in cognitive ability, electrophysiology, and homeostasis of neurotransmission and blood flow in the cerebrum. It is observed in patients with chronic liver disease and cirrhosis wh…

Intra-Substance Steroid Injection for Full-Thickness Supraspinatus Tendon Rupture Open

Waqas Haleem, Ahmad Raza Khan, Abdul Hamid, Tahir Hussain, Mueez Waqar , et al. · 2025

Full-thickness rotator cuff tears, particularly of the supraspinatus tendon, cause significant pain and disability. Although corticosteroid injections are widely used for shoulder pathologies, their role in managing complete tendon rupture…

Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review Open

Suparna Das, Paul R. Kasher, Mueez Waqar, Adrian Parry‐Jones, Hiren C. Patel · 2024

A cerebral arteriovenous malformation (cAVM) is an abnormal tangle of cerebral blood vessels. The consensus document by the Joint Writing Group (JWG) highlighted which cAVM features should be recorded. Subsequent publications have reported…

Utility of routine postoperative imaging in adults undergoing primary ventriculoperitoneal shunts Open

Adnan Raed Alnaser, A. Alnsour, Omar Pathmanaban, Helen Maye, Catherine McMahon , et al. · 2024

Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review Open

Suparna Das, Paul R. Kasher, Mueez Waqar, Adrian Parry‐Jones, Hiren C. Patel · 2024

A cerebral arteriovenous malformation (cAVM) is an abnormal tangle of cerebral blood vessels. The consensus document by the Joint Writing Group (JWG) highlighted which cAVM features should be recorded. Subsequent publications have reported…

Venous thromboembolism chemical prophylaxis after skull base surgery Open

Mueez Waqar, Omar Mohammed Yaseen, Annabel Chadwick, Jing Xian Lee, Ghazn Khan , et al. · 2024

Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study Open

Daniel Lewis, Ka‐Loh Li, Mueez Waqar, David Coope, Omar Pathmanaban , et al. · 2024

A key limitation of current dynamic contrast enhanced (DCE) MRI techniques is the requirement for full-dose gadolinium-based contrast agent (GBCA) administration. The purpose of this feasibility study was to develop and assess a new low GB…

Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review Open

Suparna Das, Paul R. Kasher, Mueez Waqar, Adrian Parry‐Jones, Hiren C. Patel · 2023

A cerebral arteriovenous malformation (cAVM) is an abnormal tangle of cerebral blood vessels. The consensus document by the Joint Writing Group (JWG) highlighted which cAVM features should be recorded. Subsequent publications h…

LOW-GRADE GLIOMAS IN OLDER PATIENTS: A MATCHED PROPENSITY-SCORING ANALYSIS TO DETERMINE SEIZURE OUTCOMES AND PROGNOSIS Open

Jing Xian Lee, Mueez Waqar, Michael Younis, Helen Maye, Matthew Bailey , et al. · 2023

AIMS Low-grade gliomas (LGG) are associated with significant morbidity and age is assumed to be a negative prognostic factor. The aim of this study was to compare outcomes between older patients with LGGs and a matched cohort of younger pa…

IMAGING HABITAT CHANGES AFTER PREOPERATIVE RADIOTHERAPY FOR GLIOBLASTOMA: UTILISATION OF A BIOINFORMATICS AND MACHINE LEARNING PIPELINE TO CHARACTERISE REGIONAL TREATMENT RESPONSE Open

Mueez Waqar, Petra Van-Houdt, Eline Hessen, Daniel Lewis, Ka‐Loh Li , et al. · 2023

AIMS Imaging of tumour habitats is a novel technique to assess regional treatment response by defining tumour ‘habitats’, which are regions with shared imaging characteristics. Here, we describe a novel pipeline to characterise imaging hab…

PREOPERATIVE BRAIN IRRADIATION IN GLIOBLASTOMA (POBIG TRIAL): FEASIBILITY AND EVALUATION OF TREATMENT RESPONSE IN ENHANCING AND NON-ENHANCING REGIONS Open

Mueez Waqar, Federico Roncaroli, Ibrahim Djoukhadar, Lisa Withington, Christopher Golby , et al. · 2023

AIMS Patients with glioblastoma have dismal outcomes and there is an urgent need for new treatment modalities. The POBIG trial is the first to evaluate the safety and feasibility of single-fraction preoperative radiotherapy for newly diagn…

Perioperative Means to Prevent Surgical Site Infections following Elective Craniotomies: A Single-Center Experience Open

Francesca Colombo, Helen Maye, Eva Bourama, Mueez Waqar, Konstantina Karabatsou , et al. · 2023

Background Postoperative surgical site infections are a recognized complication following craniotomies with an associated increase in morbidity and mortality. Several studies have attempted to identify bundles of care to reduce the inciden…

WITHDRAWN: Reporting of angiographic studies in patients diagnosed with a cerebral Arteriovenous Malformation: A systematic review Open

Suparna Das, Paul R. Kasher, Mueez Waqar, Adrian Parry‐Jones, Hiren C. Patel · 2023

This article has been withdrawn at the request of the authors. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-wi…

Study protocol: PreOperative Brain Irradiation in Glioblastoma (POBIG) – A phase I trial Open

Mueez Waqar, Federico Roncaroli, Ibrahim Djoukhadar, Leila Akkari, Claire O’Leary , et al. · 2023

NCT03582514 (clinicaltrials.gov).

Visualising spatial heterogeneity in glioblastoma using imaging habitats Open

Mueez Waqar, Petra J. van Houdt, Eline Hessen, Ka‐Loh Li, Xiaoping Zhu , et al. · 2022

Glioblastoma is a high-grade aggressive neoplasm characterised by significant intra-tumoral spatial heterogeneity. Personalising therapy for this tumour requires non-invasive tools to visualise its heterogeneity to monitor treatment respon…

CTNI-66. THE PREOPERATIVE BRAIN IRRADIATION IN GLIOBLASTOMA (POBIG) STUDY: A NOVEL TREATMENT PARADIGM TO IMPROVE OUTCOMES? Open

Gerben Borst, Mueez Waqar, Catherine McBain, W. G. Beasley, Christopher Golby , et al. · 2022

OBJECTIVE The Preoperative Brain Irradiation in Glioblastoma (POBIG) study evaluates for the first time the safety, feasibility, and impact of single fraction preoperative radiotherapy in newly diagnosed glioblastoma patients. METHODS Oper…

NIMG-40. RAPID EARLY PROGRESSION (REP) OF GLIOBLASTOMA IS AN INDEPENDENT NEGATIVE PROGNOSTIC FACTOR: RESULTS FROM A SYSTEMATIC REVIEW AND META-ANALYSIS Open

Mueez Waqar, Federico Roncaroli, Eric J. Lehrer, Joshua D. Palmer, Javier Villanueva‐Meyer , et al. · 2022

INTRODUCTION In patients with newly-diagnosed glioblastoma, rapid early progression (REP) refers to tumour regrowth between surgery and postoperative chemoradiotherapy. This systematic review and meta-analysis appraised published data on R…

Rapid Early Progression (REP) of Glioblastoma Is an Independent Negative Prognostic Factor: Results From a Systematic Review and Meta-Analysis Open

Mueez Waqar, Federico Roncaroli, Eric J. Lehrer, Joshua D. Palmer, Javier Villanueva-Meyer , et al. · 2022

AIMS In patients with newly-diagnosed glioblastoma, rapid early progression (REP) refers to tumour regrowth between surgery and postoperative chemoradiotherapy. This systematic review and meta-analysis aimed to appraise published data on R…

Delivering Large-Scale Neurosurgical Studies in the UK: The Impact of Trainees Open

Ajai Chari, Rory J. Piper, Ellie Edlmann, Julie Woodfield, Paul M. Brennan , et al. · 2022

Early Therapeutic Interventions for Newly Diagnosed Glioblastoma: Rationale and Review of the Literature Open

Mueez Waqar, Daniel M. Trifiletti, Catherine McBain, James P.B. O’Connor, David Coope , et al. · 2022

Purpose of Review Glioblastoma is the commonest primary brain cancer in adults whose outcomes are amongst the worst of any cancer. The current treatment pathway comprises surgery and postoperative chemoradiotherapy though unresectable diff…

Rapid early progression (REP) of glioblastoma is an independent negative prognostic factor: Results from a systematic review and meta-analysis Open

Mueez Waqar, Federico Roncaroli, Eric J. Lehrer, Joshua D. Palmer, Javier Villanueva-Meyer , et al. · 2022

Background In patients with newly diagnosed glioblastoma, rapid early progression (REP) refers to tumor regrowth between surgery and postoperative chemoradiotherapy. This systematic review and meta-analysis appraised previously published d…

Venous thromboembolism chemical prophylaxis after endoscopic trans-sphenoidal pituitary surgery Open

Mueez Waqar, Annabel Chadwick, James P. Kersey, Daniel Horner, Tara Kearney , et al. · 2021

Cerebral and tumoral blood flow in adult gliomas: a systematic review of results from magnetic resonance imaging Open

Mueez Waqar, Daniel Lewis, Erjon Agushi, Matthew Gittins, Alan Jackson , et al. · 2021

Objective: Blood flow is the rate of blood movement and relevant to numerous processes, though understudied in gliomas. The aim of this review was to pool blood flow metrics obtained from MRI modalities in adult supratentorial gliomas. Met…

Value of Early Post-Operative Growth Hormone Testing in Predicting Long-Term Remission and Residual Disease after Transsphenoidal Surgery for Acromegaly Open

Yi Yuen Wang, Mueez Waqar, Ahmed A Abou-Zeid, Tara Kearney, Carmela Caputo , et al. · 2021

Introduction: Surgical remission for acromegaly is dependent on a number of factors including tumour size, invasiveness, and surgical expertise. We studied the value of early post-operative growth hormone (GH) level as a pred…

Aneurysmal intra-renal arteriovenous malformation: A rare occurrence Open

O.F. Rehman, Muhammad Umair, Mueez Waqar, Badar Murtaza, Aadil Khan , et al. · 2020

Pre- and postoperative need for pituitary hormone replacement in non-adenomatous sellar and parasellar lesions: importance of the sellar encroachment score Open

Mueez Waqar, Shiva Rampersad, David B. Bennett, Tara Kearney, Kanna Gnanalingham · 2020

Quantitative analysis of medical students’ and physicians’ knowledge of degenerative cervical myelopathy Open

Mueez Waqar, Jane Wilcock, Jayne Garner, Benjamin M. Davies, Mark Kotter · 2020

Objectives We have previously identified a delay in general practitioner (GP) referrals for patients with degenerative cervical myelopathy (DCM). The aim of this study was to evaluate whether an education gap existed for DCM along the GP t…

Management evaluation of metastasis in the brain (MEMBRAIN)—a United Kingdom and Ireland prospective, multicenter observational study Open

Josephine Jung, Jignesh Tailor, Emma Dalton, Laurence Glancz, Joy Roach , et al. · 2019

Background In recent years an increasing number of patients with cerebral metastasis (CM) have been referred to the neuro-oncology multidisciplinary team (NMDT). Our aim was to obtain a national picture of CM referrals to assess referral v…

Mueez Waqar YOU? Author Swipe