Muhammad Akram Khan
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View article: Effects of Thyroid Hormone Replacement Therapy on Lipid Profiles in Patients With Hypothyroidism
Effects of Thyroid Hormone Replacement Therapy on Lipid Profiles in Patients With Hypothyroidism Open
View article: POSTOPERATIVE WOUND INFECTION RATES FOLLOWING ELECTIVE VS. EMERGENCY LAPAROTOMIES: A COMPARATIVE STUDY
POSTOPERATIVE WOUND INFECTION RATES FOLLOWING ELECTIVE VS. EMERGENCY LAPAROTOMIES: A COMPARATIVE STUDY Open
Background: Wound infection after surgery is a leading source of morbidity after abdominal surgery, especially laparotomies. The increased infection extends the hospital stays, discomfort of the patient, and healthcare expenses. Emergency …
View article: The Conflict between Metaphysical and Human Agencies in Thomas Hardy's The Mayor of Casterbridge.
The Conflict between Metaphysical and Human Agencies in Thomas Hardy's The Mayor of Casterbridge. Open
The present paper explores The Mayor of Casterbridge by Thomas Hardy for understanding the author’s metaphysical perspectives--particularly his stance vis-a-vis the role of metaphysical Power and human free will in determining not only the…
View article: Mechanotransduction Mediated by <scp>PDLIM5</scp> : The Critical Role of Serpin <scp>E2</scp> /Integrin β3‐Cytoskeleton‐Nucleoskeleton Axis in Mechanical Osteogenic Programming
Mechanotransduction Mediated by <span>PDLIM5</span> : The Critical Role of Serpin <span>E2</span> /Integrin β3‐Cytoskeleton‐Nucleoskeleton Axis in Mechanical Osteogenic Programming Open
Despite the regenerative and self‐repair capabilities of bone tissues, significant bone loss can result in substantial bone defects. This study was aimed at investigating the role and underlying mechanisms of the mechanosensitive protein P…
View article: Frequency of Advanced Liver Fibrosis among Inactive Hepatitis B Virus Carriers: A Cross-Sectional Analysis
Frequency of Advanced Liver Fibrosis among Inactive Hepatitis B Virus Carriers: A Cross-Sectional Analysis Open
Objective: To determine the frequency of advance fibrosis in Hepatitis B virus (HBV) inactive carriers. Methodology: A cross-sectional study was conducted at the Gastroenterology Outpatient Department (OPD) of AIMS, from September 2020, to…
View article: Sleep Patterns and Long-Lasting Risk of Diabetes Mellitus Type 2 in Females with a History of Gestational Diabetes Mellitus
Sleep Patterns and Long-Lasting Risk of Diabetes Mellitus Type 2 in Females with a History of Gestational Diabetes Mellitus Open
Background: Gestational diabetes mellitus is a type of hyperglycemia that occurs or is diagnosed during pregnancy. The state of sleep is becoming a crucial public health concern globally. Methodology: It was a prospective cohort study. 38 …
View article: Drug-induced hypoglycemia in a patient with Type 2 diabetes and renal impairment: A case report
Drug-induced hypoglycemia in a patient with Type 2 diabetes and renal impairment: A case report Open
Hypoglycemia is a serious adverse effect in the pharmacological treatment of Type 2 diabetes mellitus (T2DM), exacerbated by comorbidities that affect drug metabolism and clearance. This report describes a case involving a 61-year-old man …
View article: <span><span>Leaving No One Behind in the Fight Against Climate Change: Governance, Social Capital, and Community Action</span></span>
<span><span>Leaving No One Behind in the Fight Against Climate Change: Governance, Social Capital, and Community Action</span></span> Open
View article: DOCTRINAL ISSUES PERTAINING TO SOME TYPES OF THE PEOPLE OF THE BOOK IN THE STATES OF PEACE AND WAR
DOCTRINAL ISSUES PERTAINING TO SOME TYPES OF THE PEOPLE OF THE BOOK IN THE STATES OF PEACE AND WAR Open
View article: A COMPARATIVE STUDY OF GLUCOSE INTOLERANCE AND INSULIN RESISTANCE IN INDIVIDUALS USING INSULIN VS. ORAL HYPOGLYCEMIC DRUGS
A COMPARATIVE STUDY OF GLUCOSE INTOLERANCE AND INSULIN RESISTANCE IN INDIVIDUALS USING INSULIN VS. ORAL HYPOGLYCEMIC DRUGS Open
Introduction: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia resulting from defects in insulin secretion, insulin action, or both. Two primary forms of diabetes treatment include insulin therapy and oral …
View article: Corrigendum to ‘Relation of Gender to Atherosclerotic Plaque Characteristics by Differing Angiographic Stenosis Severity’ The American Journal of Cardiology, Volume 204, 1 October 2023, Pages 276-283
Corrigendum to ‘Relation of Gender to Atherosclerotic Plaque Characteristics by Differing Angiographic Stenosis Severity’ The American Journal of Cardiology, Volume 204, 1 October 2023, Pages 276-283 Open
View article: Comparative study of physicochemical and functional properties of different buckwheat varieties and their milling fractions
Comparative study of physicochemical and functional properties of different buckwheat varieties and their milling fractions Open
The present work evaluated the physicochemical and functional characteristics of different indigenous buckwheat varieties grown in Gilgit Baltistan, Pakistan, using grains and milled flour (fine flour, coarse flour, bran, and husk). Result…
View article: Relation of Gender to Atherosclerotic Plaque Characteristics by Differing Angiographic Stenosis Severity
Relation of Gender to Atherosclerotic Plaque Characteristics by Differing Angiographic Stenosis Severity Open
It is unknown whether gender influences the atherosclerotic plaque characteristics (APCs) of lesions of varying angiographic stenosis severity. This study evaluated the imaging data of 303 symptomatic patients from the derivation arm of th…
View article: Mechanical sensor PDLIM5 promotes the osteogenesis of human adipose-derived stem cells through microfilament alterations
Mechanical sensor PDLIM5 promotes the osteogenesis of human adipose-derived stem cells through microfilament alterations Open
View article: β-hydroxybutyrate attenuates demyelination, modulates microglial phenotype and supports blood-brain barrier integrity in a cuprizone-induced mouse model of demyelination
β-hydroxybutyrate attenuates demyelination, modulates microglial phenotype and supports blood-brain barrier integrity in a cuprizone-induced mouse model of demyelination Open
β-hydroxybutyrate has been reported to have neuroprotective activity. In this study, the neuroprotective effects of BHB were investigated on a demyelination model, the cuprizone model. We found that BHB reduced demyelination, which was con…
View article: The Deep Learning based Smart Navigational Stick for Blind People
The Deep Learning based Smart Navigational Stick for Blind People Open
Blind and visually impaired people find difficulty in detecting obstacles and recognizing people in their way, which makes it dangerous for them to walk, to work, or to go in a crowded area/place. They have to be cautious all the time to m…
View article: Anatomical Aspects and Role of Acupoints and Meridians Adopted in Acupuncture Technique
Anatomical Aspects and Role of Acupoints and Meridians Adopted in Acupuncture Technique Open
This chapter enumerates the crucial role of acupoints which are simple manipulations at specific points of the body and the interconnected pathways known as meridians in the operation of acupuncture, a practice of traditional Chinese medic…
View article: Diabetes, Atherosclerosis and Stenosis by AI
Diabetes, Atherosclerosis and Stenosis by AI Open
Objectives: This study evaluates the relationship between atherosclerotic plaque characteristics (APCs) and angiographic stenosis severity in patients with and without diabetes. Background: Whether APCs differ based on lesion severity a…
View article: Exploring The Unconscious Motives in The Short Story the Kite by Somerset Maugham
Exploring The Unconscious Motives in The Short Story the Kite by Somerset Maugham Open
The article focuses on the influence of the Freudian psychoanalytic theories and the in the riveting writings of William Somerset Maugham. This article has narrowed down its focus on the only one enthralling short story by Maugham, namely …
View article: Extraction and determination of bioactive compounds and antioxidant activity of buckwheat seed milling fractions
Extraction and determination of bioactive compounds and antioxidant activity of buckwheat seed milling fractions Open
Buckwheat is a precious source of various bioactive compounds like phenolics, flavonoids, rutin, and quercetin, etc. This research work was performed to harvest the nutraceutical potential of indigenous buckwheat varieties and their millin…
View article: Lamin A/C-Dependent Translocation of Megakaryoblastic Leukemia-1 and β-Catenin in Cyclic Strain-Induced Osteogenesis
Lamin A/C-Dependent Translocation of Megakaryoblastic Leukemia-1 and β-Catenin in Cyclic Strain-Induced Osteogenesis Open
Lamins are intermediate filaments that play a crucial role in sensing mechanical strain in the nucleus of cells. β-catenin and megakaryoblastic leukemia-1 (MKL1) are critical signaling molecules that need to be translocated to the nucleus …
View article: Critical Discourse Analysis of Pakistani Foreign Minister Qureshi’s Speech at UN in 2021: A Sociopolitical Perspective
Critical Discourse Analysis of Pakistani Foreign Minister Qureshi’s Speech at UN in 2021: A Sociopolitical Perspective Open
This paper is based on the Critical Discourse Analysis approach to explore Pakistani Foreign Minister Shah Mehmood Qureshi’s speech at the UN in 2021 in a sociopolitical context. The researchers, by applying Fairclough’s 3D model, investig…
View article: Effects of nitro-butoxyl- and butyl-esters of non-steroidal anti-inflammatory drugs compared with parent compounds on the contractility of digital arterial smooth muscle from the fallow deer (Dama dama)
Effects of nitro-butoxyl- and butyl-esters of non-steroidal anti-inflammatory drugs compared with parent compounds on the contractility of digital arterial smooth muscle from the fallow deer (Dama dama) Open
View article: Analyzing The Farewell Sermon of the Prophet Muhammad (pbuh) A Critical Perspective
Analyzing The Farewell Sermon of the Prophet Muhammad (pbuh) A Critical Perspective Open
Critical Discourse Analysis considers language use to be a form of social practice, and it is frequently used in political discourse, including written, verbal and visual public speeches. The last sermon of the Holy Prophet Muhammad (PBUH)…
View article: Study on the Extracting Technology for Antioxidant Oligopeptides from Donkey Meat by Two-Step Enzymatic Hydrolysis
Study on the Extracting Technology for Antioxidant Oligopeptides from Donkey Meat by Two-Step Enzymatic Hydrolysis Open
Coronavirus disease 2019 (COVID-19) is a pandemic and this disease has infected millions of people globally now.COVID-19 is caused by a novel beta coronavirus strain known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Onc…
View article: Synthesis and &lt;i&gt;In Vitro&lt;/i&gt; Anti-Helicobacter and Anti-Staphylococcal Activities of Novel Diaryldisulfides and Diarylthiosulfonates
Synthesis and <i>In Vitro</i> Anti-Helicobacter and Anti-Staphylococcal Activities of Novel Diaryldisulfides and Diarylthiosulfonates Open
Arylthiols were reacted with acrylonitrile under basic conditions to form the corresponding aryl sulfides which were oxidised with sodium metaperiodate in aqueous methanol to yield 3-arylsulphinylpropanenitriles that upon thermolysis in re…
View article: On The Reduction of Inaccuracies in Drought Monitoring - A Novel Blended Procedure for Standardized Type Drought Indicators
On The Reduction of Inaccuracies in Drought Monitoring - A Novel Blended Procedure for Standardized Type Drought Indicators Open
Due to climate change and an increasing temperature, drought is prevailing in several parts of the globe. Therefore, drought monitoring is a challenging task in hydrology and water management research. Drought is occurring recurrently in v…
View article: Knowledge level of drip irrigation farmers about drip irrigation technology
Knowledge level of drip irrigation farmers about drip irrigation technology Open
The present study was carried out during 2013 in the Durg district of Chhattisgarh state. This study was conducted in randomly selected 8 villages of two purposively selected blocks i.e. Durg and Dhamdha located in Durg district. The aim o…
View article: Compartmentalized Neuronal Culture for Viral Transport Research
Compartmentalized Neuronal Culture for Viral Transport Research Open
Neuron-invading viruses usually enter via the peripheral organs/tissues of their mammalian hosts and are transported to the neurons. Virus trafficking is critical for transport or spread within the nervous system. Primary culture of neuron…
View article: Riba in Islamic finance: Some fresh insights
Riba in Islamic finance: Some fresh insights Open
In present-day Islamic finance, all forms of interest are considered riba , which is prohibited in the Qur’an. However, this definition of riba creates several problems in everyday business transactions. The Islamic financial institutio…