Muhammad Hanafi
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View article: Novel Trinorditerpene from Dysoxylum parasiticum (Osbeck) Kosterm: Leaf Extract with Cytotoxic, Antioxidant and α-Glucosidase Inhibitory Activities
Novel Trinorditerpene from Dysoxylum parasiticum (Osbeck) Kosterm: Leaf Extract with Cytotoxic, Antioxidant and α-Glucosidase Inhibitory Activities Open
Natural products derived from plants have been extensively developed as alternative medicines due to their relatively minimal side effects. Here we present the purification and characteristics of parasitic acid, a novel trinorditerpene fro…
View article: Electrochemical and computational investigation of Tinospora cordifolia fractions as a novel corrosion inhibitor for carbon steel in seawater medium
Electrochemical and computational investigation of Tinospora cordifolia fractions as a novel corrosion inhibitor for carbon steel in seawater medium Open
This study employed electrochemical techniques and computational analyses to evaluate the efficacy of Tinospora cordifolia fraction (TCF) as an anticorrosion agent for carbon steel in a seawater medium. Electrochemical methods were employe…
View article: Kojic Acid from the Ethyl Acetate Fraction of Terminalia catappa Linn Fruit Flesh and its anti-cancer activity against HeLa cells
Kojic Acid from the Ethyl Acetate Fraction of Terminalia catappa Linn Fruit Flesh and its anti-cancer activity against HeLa cells Open
The ethyl acetate fraction of Terminalia catappa Linn. fruit flesh has anti-cancer activity against HeLa cells, with IC50 value is =165.37 ppm. The aim of this research is to isolate active anticancer compound from the ethyl acetate fracti…
View article: Formulation of Face Serum Combining Pedada Leaf Extract (Sonneratia caseolaris L.) and Kencur Rhizome Extract (Kaempferia galanga L.) As an Antioxidant Cosmetic Preparation
Formulation of Face Serum Combining Pedada Leaf Extract (Sonneratia caseolaris L.) and Kencur Rhizome Extract (Kaempferia galanga L.) As an Antioxidant Cosmetic Preparation Open
Plants containing natural bioactive compounds with antioxidant activity have the potential to be utilized and formulated into cosmetic products. Pedada (Sonneratia caseolaris L.) leaves, a type of mangrove plant and aromatic ginger (Kaempf…
View article: Coffee plant disease identification system using the certainty factor method
Coffee plant disease identification system using the certainty factor method Open
The cultivation of the coffee plant is significant in the field of agriculture and is practiced worldwide, especially in Indonesia, as a major producer. Farmers find it difficult to promptly identify and treat the disease, resulting in hug…
View article: Phytochemical Constituents and Evaluation of Lipoxygenase Activity of Tetracera Macrophylla Twigs Wall.Ex Hook.f.& Thoms
Phytochemical Constituents and Evaluation of Lipoxygenase Activity of Tetracera Macrophylla Twigs Wall.Ex Hook.f.& Thoms Open
Lipoxygenase is an enzyme that catalyzes the formation of leukotriene, which is involved in various diseases such as asthma, osteoporosis and atherosclerosis. Inhibition of this enzyme can overcome inflammatory diseases. Tetracera macroph…
View article: Unveiling green corrosion inhibitor of Aloe vera extracts for API 5L steel in seawater environment
Unveiling green corrosion inhibitor of Aloe vera extracts for API 5L steel in seawater environment Open
This study evaluated Aloe vera extract as a green inhibitor to prevent corrosion in seawater environments. A. vera extract was produced by maceration with methanol–water at room temperature. Electrochemical techniques were used to evaluat…
View article: Investigation of a novel biocide material for biocorrosion in simulated seawater: A case study on Tinospora cordifolia extract
Investigation of a novel biocide material for biocorrosion in simulated seawater: A case study on Tinospora cordifolia extract Open
This case report investigates the preventive effect of Tinospora cordifolia extract on biocorrosion induced by Pseudomonas aeruginosa on mild steel API 5L in the simulated seawater medium. Electrochemical techniques, spectroscopic techniqu…
View article: Phytochemical Constituents, Anti-Diabetic and Antioxidant Activities of Methanol Extracts of Diospyros malabarica (Desr.) Kostel Leaves and Stem Bark
Phytochemical Constituents, Anti-Diabetic and Antioxidant Activities of Methanol Extracts of Diospyros malabarica (Desr.) Kostel Leaves and Stem Bark Open
Diospyros malabarica (Desr.) Kostel is widely used in traditional medicine as an antioxidant and anti-diabetic agent. This study aims to evaluate the phytochemical constituents, the antioxidant and anti-diabetic activities of the methanol …
View article: Pharmacognostic Evaluation and Antioxidant Activities of Tetracera indica (Christm. and Panz.) Merr
Pharmacognostic Evaluation and Antioxidant Activities of Tetracera indica (Christm. and Panz.) Merr Open
The community uses Tetracera indica (Christm. and Panz.) Merr extensively as a traditional medicine. This plant was the main source of raw materials for herbal medicinal products, so identification was needed to ensure its authenticity thr…
View article: ISOLASI ASAM 3β-HIDROKSI-5-GLUTINEN-28-OAT DARI KULIT BATANG ASAM KANDIS (Garcinia cymosa) DAN AKTIVITAS SITOTOKSIKNYA TERHADAP SEL KANKER PAYUDARA MCF-7
ISOLASI ASAM 3β-HIDROKSI-5-GLUTINEN-28-OAT DARI KULIT BATANG ASAM KANDIS (Garcinia cymosa) DAN AKTIVITAS SITOTOKSIKNYA TERHADAP SEL KANKER PAYUDARA MCF-7 Open
The Garcinia genus comes from the Clusiaceae family which grows a lot in the tropical forests of Indonesia. This genus is reported to contain many secondary metabolites, one of which is triterpenoid which is useful as a cytotoxic, anti-oxi…
View article: Chisocheton pentandrus (Blanco) Merr. leaf as a potential antioxidant and α-glucosidase inhibitory agent
Chisocheton pentandrus (Blanco) Merr. leaf as a potential antioxidant and α-glucosidase inhibitory agent Open
Indonesia is one of the countries with the highest diversity of plants worldwide, including the Chisocheton genus. The Chisocheton genus has been widely used in traditional medicine due to a variety of compounds with different activities, …
View article: Evaluation of Morinda citrifolia extract as sustainable inhibitor for mild steel in saline environment
Evaluation of Morinda citrifolia extract as sustainable inhibitor for mild steel in saline environment Open
In this study, the Morinda citrifolia extract was evaluated as a sustainable inhibitor of mild steel in saline environments. The work aimed to determine the inhibition efficiency of new active material for metal corrosion inhibition. The p…
View article: FLAVONOID COMPOUND FROM ETHANOL EXTRACT OF Diospyros celebica LEAVES AS AN ANTIDIABETIC CANDIDATE
FLAVONOID COMPOUND FROM ETHANOL EXTRACT OF Diospyros celebica LEAVES AS AN ANTIDIABETIC CANDIDATE Open
Ethnobotanically in Indonesia, Diospyros celebica Bakh is recognized as having antidiabetic activity. This study aimed to isolate antidiabetic compounds from the leaves of Eboni (Diospyros celebica). D. celebica leaves were dried and extra…
View article: Phytochemical Contents and Antioxidant Activity of Dysoxylum densiflorum Extract and Fractions
Phytochemical Contents and Antioxidant Activity of Dysoxylum densiflorum Extract and Fractions Open
Many studies have been carried out on the use of natural product compounds as an alternative medicine. Dysoxylum densiflorum is a plant that is commonly found in tropical countries and is used as an alternative treatment in local communiti…
View article: Enhancing the corrosion inhibition performance of Tinospora cordifolia extract using different fractions of methanol solvent on carbon steel corrosion in a seawater-simulated solution
Enhancing the corrosion inhibition performance of Tinospora cordifolia extract using different fractions of methanol solvent on carbon steel corrosion in a seawater-simulated solution Open
The present study investigates the inhibition potential of Tinospora cordifolia extract in combination with different methanol solvents on the corrosion of carbon steel in artificial seawater environments. Potentiodynamic polarization (PDP…
View article: Total phenolic and flavonoid contents of Aphanamixis polystachya (Wall.) R.Parker leaf extract and its potential as antioxidant and inhibitor of α-glucosidase
Total phenolic and flavonoid contents of Aphanamixis polystachya (Wall.) R.Parker leaf extract and its potential as antioxidant and inhibitor of α-glucosidase Open
Indonesia is one of the countries with the highest plant diversity in the world, including the Aphanamixis genus, and they use the plants in this genus as traditional medicine. The genus Aphanamixis has a wide variety of compounds with dif…
View article: Untargeted metabolomics analysis of Rhinachantus nasutus (L.) Kurz stem bark using HRMS UHPLC-Q-Orbitrap and evaluation of antioxidant capacity and α-glucosidase inhibitory activity
Untargeted metabolomics analysis of Rhinachantus nasutus (L.) Kurz stem bark using HRMS UHPLC-Q-Orbitrap and evaluation of antioxidant capacity and α-glucosidase inhibitory activity Open
Preparations of the roots, stems, and leaves of Rhinachantus nasutus (L.) Kurz (RNK) have been used empirically in traditional medicine to treat diabetes, eczema, pulmonary tuberculosis, herpes, hepatitis, and hypertension for centuries. T…
View article: Parameter processes and their impact on Tinospora cordifolia stem extracts for antibacterial and antioxidant materials
Parameter processes and their impact on Tinospora cordifolia stem extracts for antibacterial and antioxidant materials Open
This work extracted the Tinospora cordifolia stem for antibacterial and antioxidant materials. The stems of T. cordifolia were extracted by using a simple maceration method. The effect of three independent variables (solvent ratios, temper…
View article: Identification of an Oligostilbene, Vaticanol B, from <i>Dryobalanops aromatica</i> Leaves as an Antiviral Compound against the Hepatitis C Virus
Identification of an Oligostilbene, Vaticanol B, from <i>Dryobalanops aromatica</i> Leaves as an Antiviral Compound against the Hepatitis C Virus Open
Chronic hepatitis C virus (HCV) infection can lead to liver cirrhosis and hepatocellular carcinoma. Although current medications using direct-acting antivirals (DAAs) are highly effective and well-tolerated for treating patients with chron…
View article: Morelloflavone and Molecular Docking from Stembark of Chisocheton lasiocarpus and Its Cytotoxic Activity Against Breast Cancer Mcf-7 Cell Lines
Morelloflavone and Molecular Docking from Stembark of Chisocheton lasiocarpus and Its Cytotoxic Activity Against Breast Cancer Mcf-7 Cell Lines Open
Chisocheton is a plant of the Meliaceae family which has been known as a source of limonoids, triterpenoids, steroids, alkaloids and phenolics. This plant is the second largest in the Meliaceae, with 53 species widely distributed in tropic…
View article: An ethnopharmacology study of Indonesian medicinal plants in Gunung Sari village as dipeptidyl peptidase-IV inhibitor
An ethnopharmacology study of Indonesian medicinal plants in Gunung Sari village as dipeptidyl peptidase-IV inhibitor Open
During an ethnopharmacology study of traditional antidiabetic treatment in Gunung Sari village, Bogor region, Indonesia, fifteen traditional medicinal plants were selected, collected and prepared as crude extracts. Among fifteen plants, on…
View article: The Analysis of Artabotrys hexapetalus Stem Bark and Leaf Ethanol Extract as α-Glucosidase Inhibitor in Relation to Antioxidant Activity, Phenolic, and Flavonoid Contents Using In Vitro Analysis, LC-MS, Machine Learning and Molecular Docking
The Analysis of Artabotrys hexapetalus Stem Bark and Leaf Ethanol Extract as α-Glucosidase Inhibitor in Relation to Antioxidant Activity, Phenolic, and Flavonoid Contents Using In Vitro Analysis, LC-MS, Machine Learning and Molecular Docking Open
Artabotrys hexapetalus is one of Artabotrys species that can be found in Asia, such as Sri Lanka, India, China, Malaysia, Indonesia, and other Southeast Asian countries. This plant is used traditionally as a herbal medicine. The aims of th…
View article: Isolation and identification of bioactive compounds from Tinospora cordifolia stem extracts as antibacterial materials in seawater environments
Isolation and identification of bioactive compounds from Tinospora cordifolia stem extracts as antibacterial materials in seawater environments Open
The Tinospora genus is widely utilized because of its numerous bioactive compounds. This work aimed to isolate the bioactive constituents and antibacterial activities of the T. cordifolia plant. Maceration, column chromatography, and thin-…
View article: Pharmacognostic evaluation and antioxidant capacity of Tetracera macrophylla Hook. F. & Thoms twigs
Pharmacognostic evaluation and antioxidant capacity of Tetracera macrophylla Hook. F. & Thoms twigs Open
Context: Tetracera macrophylla Hook. f. & Thoms is used empirically in traditional medicine, specifically the twig, to treat dysentery, diarrhea, diabetes, and tuberculosis symptoms. The plant contains phenolic and flavonoid compounds that…
View article: Green Synthesized Plant-Based Metallic Nanoparticles for Antimicrobial and Anti-Corrosion Applications
Green Synthesized Plant-Based Metallic Nanoparticles for Antimicrobial and Anti-Corrosion Applications Open
Metal nanoparticles (MNPs) developed through green synthesis with various plant extracts have piqued the scientific community due to their antimicrobial and anticorrosion properties. Several synthesis methods and characteristics have been …
View article: In vitro and molecular docking of α-Glucosidase inhibitor potency from Artabotrys suaveolens leaf and stem bark
In vitro and molecular docking of α-Glucosidase inhibitor potency from Artabotrys suaveolens leaf and stem bark Open
Artabotrys suaveolens is one of the species from Artabotrys genus, one of the largest genus from Annonaceae family. This plant has been used traditionally to treat several diseases and also as emmenagogue. This research was aimed to explor…
View article: Nimonol from Chisocheton macrophyllus (Meliaceae) Seeds and Their Cytotoxic Activity against P-388 Leukaemia Cells
Nimonol from Chisocheton macrophyllus (Meliaceae) Seeds and Their Cytotoxic Activity against P-388 Leukaemia Cells Open
The Chisocheton genus belongs to the Meliaceae family which produces various structures and activities of compounds, such as antimalarial, antimicrobial, antitumor, anti-inflammatory, and cytotoxic. This plant has 53 species that are sprea…
View article: The Potential of Tinospora cordifolia Extracts as Antibacterial Material against Pseudomonas aeruginosa
The Potential of Tinospora cordifolia Extracts as Antibacterial Material against Pseudomonas aeruginosa Open
Mitigation and control of bacterial corrosion must have been prioritized for failure anticipation by corrosion associated with microorganisms. Using synthetic inhibitor for material protection from corrosion have problems because it is not…
View article: Phytochemical Screening, Antioxidant Activity, and Anti- Inflammatory Potential of Rhinachantus nasutus (L.) Kurz Flower Ethanol Extract
Phytochemical Screening, Antioxidant Activity, and Anti- Inflammatory Potential of Rhinachantus nasutus (L.) Kurz Flower Ethanol Extract Open
Aims: The purpose of this study was to determine the content of the secondary metabolite compound in the flower extract of Rhinachantus nasutus (L.) Kurz (RnK); The potential of the extract as a radical scavenger of 2,2-diphenyl-1-picrylhy…