Muhammad Imran Nisar
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View article: Nutritional management of growth faltering in infants aged under six months in Asia and Africa: study protocol for a multicentre randomised trial (BRANCH, BReAstfeediNg Counselling and management of growtH)
Nutritional management of growth faltering in infants aged under six months in Asia and Africa: study protocol for a multicentre randomised trial (BRANCH, BReAstfeediNg Counselling and management of growtH) Open
View article: The path to equitable respiratory syncytial virus prevention for infants: challenges and opportunities for global implementation
The path to equitable respiratory syncytial virus prevention for infants: challenges and opportunities for global implementation Open
The approval for a respiratory syncytial virus (RSV) maternal vaccination programme by Gavi, The Vaccine Alliance, marks substantial progress toward equitable access, with important work still to come. Several countries, most of which are …
View article: Causes and risk factors for deaths in young infants in South Asia: the ANISA prospective population-based observational cohort study
Causes and risk factors for deaths in young infants in South Asia: the ANISA prospective population-based observational cohort study Open
Introduction Strategies for reducing infant mortality require accurate, local, population-level data. We conducted a population-based observational study in three countries in South Asia to describe risk factors, causes and rates of mortal…
View article: Underlying Causes of Short Stature in Children Aged 4 to 16 Years Presenting at the Endocrine Clinic of a Tertiary Care Hospital in Pakistan
Underlying Causes of Short Stature in Children Aged 4 to 16 Years Presenting at the Endocrine Clinic of a Tertiary Care Hospital in Pakistan Open
Short stature is a frequent pediatric presentation that may arise from normal growth variants or underlying pathological conditions. In Pakistan, its burden is heightened by malnutrition, infections, and delayed healthcare-seeking behavior…
View article: Inpatient versus outpatient management of young infants with a single low-mortality-risk sign of possible serious bacterial infection in sub-Saharan Africa and south Asia: an open-label, multicentre, two-arm, randomised controlled trial
Inpatient versus outpatient management of young infants with a single low-mortality-risk sign of possible serious bacterial infection in sub-Saharan Africa and south Asia: an open-label, multicentre, two-arm, randomised controlled trial Open
Bill and Melinda Gates Foundation.
View article: Switching antibiotic therapy from injectable to oral to optimise the duration of inpatient care for young infants presenting with moderate-mortality-risk signs of possible serious bacterial infection: an open-label, multicountry, randomised controlled trial
Switching antibiotic therapy from injectable to oral to optimise the duration of inpatient care for young infants presenting with moderate-mortality-risk signs of possible serious bacterial infection: an open-label, multicountry, randomised controlled trial Open
Gates Foundation.
View article: <b>The Effectiveness of Measles Vaccination Associated Risk Factors and Complications among Children Under 5 Years in Slum Area of Karachi</b>
<b>The Effectiveness of Measles Vaccination Associated Risk Factors and Complications among Children Under 5 Years in Slum Area of Karachi</b> Open
Background: Measles remains a major cause of morbidity and mortality among children under five years in low-income settings globally, despite the availability of effective vaccination. Slum areas face amplified risk due to overcrowding, po…
View article: Association of biological, socioeconomic, and environmental factors with child development at two years of age in Bangladesh, Pakistan, and Tanzania: results from the AMANHI-ACT study
Association of biological, socioeconomic, and environmental factors with child development at two years of age in Bangladesh, Pakistan, and Tanzania: results from the AMANHI-ACT study Open
View article: Mortality Rates, and Age-Based Analysis of Ischemic Stroke in Peshawar: A Comparative Study between Urban and Rural Populations
Mortality Rates, and Age-Based Analysis of Ischemic Stroke in Peshawar: A Comparative Study between Urban and Rural Populations Open
Background: Ischemic stroke remains a major global health concern, with notable disparities in outcomes between rural and urban population in South Asia. Regional resource distribution, care disparities and demographic factors may exacerba…
View article: The human milk microbiome varies by environmental factors and is associated with infant growth: findings from the IMiC Consortium
The human milk microbiome varies by environmental factors and is associated with infant growth: findings from the IMiC Consortium Open
Human milk (HM) is a complex ecological matrix that connects mothers and infants to the surrounding environment, and promotes infant growth and health. While certain components of HM are well studied, including its macronutrient content an…
View article: How maternal morbidities impact women’s quality of life during pregnancy and postpartum in sub-Saharan Africa and South Asia: A qualitative study
How maternal morbidities impact women’s quality of life during pregnancy and postpartum in sub-Saharan Africa and South Asia: A qualitative study Open
Maternal morbidities present a major burden to the health and well-being of childbearing women. However, their impacts on women’s functional health are not well understood. This work aims to describe how maternal morbidities affect women’s…
View article: Bridging the Health Literacy Gap: Women and Community Stakeholders’ Perspectives on Maternal and Child Health Communication in Peri-urban Karachi, Pakistan
Bridging the Health Literacy Gap: Women and Community Stakeholders’ Perspectives on Maternal and Child Health Communication in Peri-urban Karachi, Pakistan Open
Health literacy significantly influences health outcomes, particularly in Low-and Middle-Income Countries. Communication of maternal and child heath messages occurs via text messages, phone calls, television, newspaper articles, and home v…
View article: Editorial: Use of artificial intelligence to improve maternal and neonatal health in low-resource settings
Editorial: Use of artificial intelligence to improve maternal and neonatal health in low-resource settings Open
View article: Correction: Wastewater metagenomics in Africa: Opportunities and challenges
Correction: Wastewater metagenomics in Africa: Opportunities and challenges Open
[This corrects the article DOI: 10.1371/journal.pgph.0004044.].
View article: Wastewater surveillance for early pathogen detection in Asia
Wastewater surveillance for early pathogen detection in Asia Open
Wastewater surveillance (WS) has emerged as an important population-based surveillance tool for early pathogen detection to inform timely public health action. Despite global guidance to initiate WS programming in Asia, the priorities and …
View article: Comparison of Self-Collected Vaginal Swabs and First-Void Urine for Detection of Human Papillomavirus in Sexually Active Girls and Women in Three South Asian Countries
Comparison of Self-Collected Vaginal Swabs and First-Void Urine for Detection of Human Papillomavirus in Sexually Active Girls and Women in Three South Asian Countries Open
Background As more countries plan and launch human papillomavirus (HPV) vaccination campaigns, reliable self-sampling methods are essential for detecting high-risk HPV (HR-HPV) types and assessing public health impact. This study compared …
View article: A systems-change approach to addressing the mortality surveillance gap in Pakistan
A systems-change approach to addressing the mortality surveillance gap in Pakistan Open
With a lack of cause of death estimation and an inadequate and fragmented Civil Registration and Vital Statistics system, Pakistan faces a significant gap in data on mortality. This poses significant challenges for health policy planning a…
View article: Protocol for the Redefining Maternal Anemia in Pregnancy and Postpartum (ReMAPP) study: A multisite, international, population-based cohort study to establish global hemoglobin thresholds for maternal anemia
Protocol for the Redefining Maternal Anemia in Pregnancy and Postpartum (ReMAPP) study: A multisite, international, population-based cohort study to establish global hemoglobin thresholds for maternal anemia Open
Background Anemia affects one in three pregnant women worldwide, with the greatest burden in South Asia and sub-Saharan Africa. During pregnancy, anemia has been linked to an increased risk of adverse maternal and neonatal health outcomes.…
View article: Factors Influencing Glycaemic Control in Adolescents with Type I Diabetes: Cross-Sectional Analysis of Individual and Parental Factors
Factors Influencing Glycaemic Control in Adolescents with Type I Diabetes: Cross-Sectional Analysis of Individual and Parental Factors Open
Type I Diabetes mellitus, Adolescents, Glycaemic control, Risk factors.
View article: Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage
Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage Open
Background: Klebsiella pneumoniae causes ~20% of sepsis in neonates, with ~40% crude mortality. A vaccine administered to pregnant women, protecting against 70% of K. pneumoniae infections, could avert ~400,000 cases and ~80,000 deaths ann…
View article: Cross-Sectional Assessment of Pigeon-Associated Environmental Exposure Pathways and Their Potential Risk for Zoonotic Disease Transmission to Humans in Urban Areas of Sindh
Cross-Sectional Assessment of Pigeon-Associated Environmental Exposure Pathways and Their Potential Risk for Zoonotic Disease Transmission to Humans in Urban Areas of Sindh Open
Urban pigeons (Columba livia domestica) are known reservoirs of multiple zoonotic pathogens, posing significant public health risks in densely populated cities. Sindh province, Pakistan, with its large urban centers, faces challenges relat…
View article: Experiences and beliefs related to exclusive breastfeeding (EBF) and early supplementation in urban slums of Karachi, Pakistan-A qualitative study
Experiences and beliefs related to exclusive breastfeeding (EBF) and early supplementation in urban slums of Karachi, Pakistan-A qualitative study Open
Exclusive breastfeeding (EBF) until six months of age is recommended as it contributes to childhood growth and development as well as protects against infections. Establishing EBF in certain settings can be difficult especially when women …
View article: Fixing the plumbing: Building interoperability between wastewater genomic surveillance datasets and systems using the PHA4GE contextual data specification
Fixing the plumbing: Building interoperability between wastewater genomic surveillance datasets and systems using the PHA4GE contextual data specification Open
The evolution of wastewater genomic surveillance (WWGS) has led to the development of many new methodologies, allowing for the broad application of WWGS for detection and monitoring of diverse pathogens and genetic markers. Variability in …
View article: Cardiovascular Risk Factors and Disease in Patients with Rheumatoid Arthritis
Cardiovascular Risk Factors and Disease in Patients with Rheumatoid Arthritis Open
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial joints, leading to progressive joint damage, deformities, and functional disability. Objective: The basic aim of this tec…
View article: The Effect of Balanced Energy-Protein Supplementation Provided to Pregnant Women on Infant Birth Weight: An Individual Participant Data Meta-Analysis
The Effect of Balanced Energy-Protein Supplementation Provided to Pregnant Women on Infant Birth Weight: An Individual Participant Data Meta-Analysis Open
View article: Infant-level and child-level predictors of mortality in low-resource settings: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort
Infant-level and child-level predictors of mortality in low-resource settings: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort Open
For the Spanish and French translations of the abstract see Supplementary Materials section.
View article: Infections do not play fair: the Charlson-Age Comorbidity Index reveals sex-specific risk in laparotomy patients in an LMIC
Infections do not play fair: the Charlson-Age Comorbidity Index reveals sex-specific risk in laparotomy patients in an LMIC Open
Background Surgical site infections (SSIs) are a major cause of increased morbidity, hospital stay, care costs, and mortality in surgical patients; these can be prognosticated by the Charlson Comorbidity Index (CCI) and accounting for age—…
View article: Correction: Feasibility and acceptability of implementing the Global Scales for Early Development (GSED) package for children 0–3 years across three countries
Correction: Feasibility and acceptability of implementing the Global Scales for Early Development (GSED) package for children 0–3 years across three countries Open
View article: Feasibility and acceptability of implementing the Global Scales for Early Development (GSED) package for children 0–3 years across three countries
Feasibility and acceptability of implementing the Global Scales for Early Development (GSED) package for children 0–3 years across three countries Open
This study generated invaluable information regarding the implementation of the GSED, including where improvements should be made and where the administered measures' comprehensibility, relevance, and acceptability needed revisions. These …
View article: Association between gestational weight gain and adverse pregnancy outcomes: cohort analysis from South Asia and Sub-Saharan Africa
Association between gestational weight gain and adverse pregnancy outcomes: cohort analysis from South Asia and Sub-Saharan Africa Open
Introduction Studies of gestational weight gain (GWG) and adverse pregnancy outcomes seldom focus on low-to-middle-income countries (LMICs), despite their high burden of morbidity and mortality. We examined GWG patterns and adverse pregnan…