Muhammad Irfan Abdul Jalal
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View article: Randomized double-blind crossover trial of a transdermal maltose dissolvable microneedle patch for topical anesthesia before intravenous cannulation for thalassemia children
Randomized double-blind crossover trial of a transdermal maltose dissolvable microneedle patch for topical anesthesia before intravenous cannulation for thalassemia children Open
The efficacy and safety of transdermal dissolvable microneedle array patch (MNAP) in enhancing topical anesthesia delivery was studied in transfusion-dependent thalassemia children who had intravenous cannulation (IVC) for blood transfusio…
View article: The efficacy and safety of lignocaine-embedded dissolvable microneedle versus EMLA for topical analgesia in adults undergoing venepuncture: A single-centre, parallel-group, double-blind randomised clinical trial protocol in a tertiary care setting
The efficacy and safety of lignocaine-embedded dissolvable microneedle versus EMLA for topical analgesia in adults undergoing venepuncture: A single-centre, parallel-group, double-blind randomised clinical trial protocol in a tertiary care setting Open
Venepuncture-associated pain is a major source of distress commonly experienced by adult patients in day-to-day clinical practice. Topical lignocaine application before venepuncture may address this issue, but this delivery approach may be…
View article: A prospective single-masked, non-inferiority, parallel-group randomized controlled trial of the efficacy of a ChatGPT-based AI chatbot to improve Boston bowel preparation scores for colonoscopy preparation: A trial protocol
A prospective single-masked, non-inferiority, parallel-group randomized controlled trial of the efficacy of a ChatGPT-based AI chatbot to improve Boston bowel preparation scores for colonoscopy preparation: A trial protocol Open
Artificial intelligence (AI) is transforming healthcare through tools like large language model chatbots. AI chatbots can simulate human conversation, provide personalized information, and interact with patients in real time. Their ease of…
View article: Gene co-expression module study identifies key genes and pathways underpinning hypercholesterolemia-induced atherosclerosis development
Gene co-expression module study identifies key genes and pathways underpinning hypercholesterolemia-induced atherosclerosis development Open
Background Familial hypercholesterolemia (FH) is a significant risk factor for atherosclerosis due to elevated levels of low-density lipoprotein (LDL) cholesterol in arterial walls. This study aimed to determine the key genes involved in t…
View article: A synonymous KCNH2 polymorphism and methadone trough level influence QTc prolongation in Kelantanese Malay recipients of methadone maintenance therapy (MMT) in Malaysia
A synonymous KCNH2 polymorphism and methadone trough level influence QTc prolongation in Kelantanese Malay recipients of methadone maintenance therapy (MMT) in Malaysia Open
Potassium voltage-gated channel subfamily H member 2 ( KCNH2 ) polymorphisms have been found to influence the heart-rate adjusted QT (QTc) intervals. We investigated the association between KCNH2 polymorphisms and QTc intervals among Malay…
View article: Bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinoma
Bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinoma Open
Background Hepatocellular carcinoma is a highly encountered primary liver malignancy, currently ranked as the third major contributor to death worldwide. This research endeavoured to establish non-invasive prognostic determinants of hepato…
View article: Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing™-Assisted Colonoscopy: A Randomized Control Trial
Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing™-Assisted Colonoscopy: A Randomized Control Trial Open
Aim: Endo-Wing™ is a soft silicone device with six wing-like projections attached at the end of the colonoscope that provides superior visualization by flattening the colonic fold and helps to maintain a central view of the colonoscope dur…
View article: Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing Assisted Colonoscopy: A Randomized Control Trial
Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing Assisted Colonoscopy: A Randomized Control Trial Open
Aim Endo-WingTM is a silicone rubber device with 6 wing-like projections attached at the end of the colonoscope that provides superior visualization by flattening the colonic fold and helps to maintain a central view of the colonoscope dur…
View article: Colorectal Cancer Screening using Immunochemical Faecal Occult Blood Testing (iFOBT) in Urban-Poor Communities in Cheras, Malaysia: A Cross-Sectional Study
Colorectal Cancer Screening using Immunochemical Faecal Occult Blood Testing (iFOBT) in Urban-Poor Communities in Cheras, Malaysia: A Cross-Sectional Study Open
Background: Colorectal cancer (CRC) is one of the most common cancers globally, with the immunochemical faecal occult blood test (iFOBT) frequently used for population level screening. This study evaluated CRC screening uptake among urban-…
View article: Risk prediction of cardiovascular disease in the Asia-Pacific region: the SCORE2 Asia-Pacific model
Risk prediction of cardiovascular disease in the Asia-Pacific region: the SCORE2 Asia-Pacific model Open
Background and Aims To improve upon the estimation of 10-year cardiovascular disease (CVD) event risk for individuals without prior CVD or diabetes mellitus in the Asia-Pacific region by systematic recalibration of the SCORE2 risk algorith…
View article: Baerveldt glaucoma implant with Supramid© ripcord stent in neovascular glaucoma: a case series
Baerveldt glaucoma implant with Supramid© ripcord stent in neovascular glaucoma: a case series Open
AIM: To report the outcome of Baerveldt glaucoma implant (BGI) with Supramid© ripcord use in neovascular glaucoma (NVG). METHODS: We retrospectively evaluated the surgical outcome of the BGI with Supramid© 3/0 ripcord stent in patients wit…
View article: The Differential Impacts of Urban Poverty on the Nutritional Status of Under-Five Children in Petaling Jaya, Malaysia During Covid-19 Pandemic: A Cross-Sectional Study in the Urban Setting
The Differential Impacts of Urban Poverty on the Nutritional Status of Under-Five Children in Petaling Jaya, Malaysia During Covid-19 Pandemic: A Cross-Sectional Study in the Urban Setting Open
View article: The Prevalence and Determinants of Child Hunger and Its Associations with Early Childhood Nutritional Status among Urban Poverty Households during COVID-19 Pandemic in Petaling District, Malaysia: An Exploratory Cross-Sectional Survey
The Prevalence and Determinants of Child Hunger and Its Associations with Early Childhood Nutritional Status among Urban Poverty Households during COVID-19 Pandemic in Petaling District, Malaysia: An Exploratory Cross-Sectional Survey Open
Child hunger was prevalent during the COVID-19 pandemic, but the extent, determinants, and impact on pre-school children aged 6 months to 7 years old from Malaysian urban poor households are still unknown. This exploratory cross-sectional …
View article: A Randomized Pilot Trial of Micronutrient Supplementation for Under-5 Children in an Urban Low-Cost Flat Community in Malaysia: A Framework for Community-Based Research Integration
A Randomized Pilot Trial of Micronutrient Supplementation for Under-5 Children in an Urban Low-Cost Flat Community in Malaysia: A Framework for Community-Based Research Integration Open
Early childhood nutritional deficiency has detrimental consequences on physical and cognitive development. We conducted a single-center, single-blind, two-arm pilot randomized no-treatment controlled trial (the Child of Urban Poverty Iron …
View article: 70 Comparative study between PIMS and Kawasaki disease
70 Comparative study between PIMS and Kawasaki disease Open
Background Kawasaki disease (kDa) is a multisystemic vasculitis affecting medium and small vessels with a predilection for the coronary arteries. It appears to be very similar to the pediatric multisystemic inflammatory syndrome (PIMS), wh…
View article: Probiotics, a promising therapy to reduce the recurrence of bacterial vaginosis in women? a systematic review and meta-analysis of randomized controlled trials
Probiotics, a promising therapy to reduce the recurrence of bacterial vaginosis in women? a systematic review and meta-analysis of randomized controlled trials Open
Introduction The evidence for probiotic efficacy in preventing bacterial vaginosis (BV) recurrences among women aged 18 years and above is sparse. We aimed to ascertain the efficacy of probiotics in preventing BV recurrences after at least…
View article: Transdermal Maltose-Based Microneedle Patch as Adjunct to Enhance Topical Anesthetic before Intravenous Cannulation of Pediatric Thalassemic Patients Receiving Blood Transfusion: A Randomized Controlled Trial Protocol
Transdermal Maltose-Based Microneedle Patch as Adjunct to Enhance Topical Anesthetic before Intravenous Cannulation of Pediatric Thalassemic Patients Receiving Blood Transfusion: A Randomized Controlled Trial Protocol Open
Intravenous cannulation is experientially traumatic to children. To minimize this, EMLA® is applied on the would-be-cannulated area before IV cannula insertion. However, the time to achieve its maximum efficacy may be affected due to incom…
View article: Role of Serum Ferritin in Predicting Outcomes of COVID-19 Infection Among Sickle Cell Disease Patients: A Systematic Review and Meta-Analysis
Role of Serum Ferritin in Predicting Outcomes of COVID-19 Infection Among Sickle Cell Disease Patients: A Systematic Review and Meta-Analysis Open
Patients with sickle cell disease (SCD) are at higher risk of getting severe COVID-19 infection. This systematic review and meta-analysis aimed to determine the role of serum ferritin in predicting ICU admission and mortality among patient…
View article: Improvement of the BT-Heartomotive Device for Avert Car Accident using MYBradyTachyHeart Mobile Application
Improvement of the BT-Heartomotive Device for Avert Car Accident using MYBradyTachyHeart Mobile Application Open
Nowadays, the pulse oximeter used in the medical device is a noninvasive sensor capable for monitoring the blood's oxygen saturation. It has been widely used in medical, fitness and clinical care. The prototype development of brady-tachy h…
View article: Bayesian Time Series Modelling of the Italian Daily Rainfall Data using Mixed Distribution
Bayesian Time Series Modelling of the Italian Daily Rainfall Data using Mixed Distribution Open
A combination of continuous and discrete elements is referred to as a mixed distribution. For example, daily rainfall data consist of zero and positive values. We aim to develop a Bayesian time series model that captures the evolution of t…
View article: Replication data for "The effect of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries"
Replication data for "The effect of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries" Open
This is the dataset for a clinical trial entitled "The effect of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries". The results obtained from the analyses of this data s…
View article: The effect of 20 mg parecoxib as an adjunct to 0.75 ropivacaine in ultrasound-guided brachial plexus block for upper limb surgery.tab
The effect of 20 mg parecoxib as an adjunct to 0.75 ropivacaine in ultrasound-guided brachial plexus block for upper limb surgery.tab Open
View article: The effect of 20 mg Parecoxib as an Adjunct to 0.75 Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries.tab
The effect of 20 mg Parecoxib as an Adjunct to 0.75 Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries.tab Open
View article: The effect of 20 mg Parecoxib as an Adjunct to 0.75 Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries.csv
The effect of 20 mg Parecoxib as an Adjunct to 0.75 Ropivacaine in Ultrasound-Guided Brachial Plexus Block for Upper Limb Surgeries.csv Open