Muhammad Ali
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View article: Biosynthesis and multifaceted roles of reactive species in plant defense mechanisms during environmental cues
Biosynthesis and multifaceted roles of reactive species in plant defense mechanisms during environmental cues Open
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are key components of plant metabolism, acting as cellular damage agents and essential signalling molecules. They play crucial roles in plant growth, development, and respon…
View article: <i>Fusobacterium nucleatum</i> Lipopolysaccharides O-Antigen Defines a Novel Siglec-7 Binding Epitope
<i>Fusobacterium nucleatum</i> Lipopolysaccharides O-Antigen Defines a Novel Siglec-7 Binding Epitope Open
Fusobacterium nucleatum (Fn) is a Gram-negative bacterium predominantly found in the human oral cavity, occasionally linked to systemic diseases, including colorectal cancer. Bacterial lipopolysaccharides (LPSs) represent one of the possib…
View article: Native genetic switch enhances heat resilience, grain quality, and yield in rice
Native genetic switch enhances heat resilience, grain quality, and yield in rice Open
This commentary describes a study showing that the natural thermo-responsive gene switch QT12 regulates rice thermotolerance by modulating endoplasmic reticulum stress and storage protein synthesis. Dual transcriptional controls optimize g…
View article: Integrating genomic tools and traditional breeding for climate-resilient cotton: A comprehensive review
Integrating genomic tools and traditional breeding for climate-resilient cotton: A comprehensive review Open
Cotton (Gossypium hirsutum L.) is a globally important fibre and cash crop, playing a crucial role in the agricultural and industrial economy. Climate change, including high and low temperatures, drought, and chilling stress, poses signifi…
View article: <b>THE</b><b> </b><b>EFFICACY</b><b> </b><b>OF</b><b> </b><b>BIOLOGICS</b><b> </b><b>IN</b><b> </b><b>INFLAMMATORY</b><b> </b><b>BOWEL DISEASE (IBD): A REVIEW</b>
<b>THE</b><b> </b><b>EFFICACY</b><b> </b><b>OF</b><b> </b><b>BIOLOGICS</b><b> </b><b>IN</b><b> </b><b>INFLAMMATORY</b><b> </b><b>BOWEL DISEASE (IBD): A REVIEW</b> Open
Inflammatory Bowel Disease (IBD), which includes Crohn’s Disease (CD) and Ulcerative Colitis (UC), is a long-term condition caused by abnormal immune responses that lead to ongoing inflammation in the gut. Its roots are complex, involving …
View article: Association of General Health, Quality of Sleep, Overuse of Cell Phone, Social Networks and Internet Addiction among Medical Sciences Students
Association of General Health, Quality of Sleep, Overuse of Cell Phone, Social Networks and Internet Addiction among Medical Sciences Students Open
Background: Mobile phones are quickly becoming the dominant communication device in people’s lives, particularly in youngsters, which carries psychological dependency towards mobile phones which leads to addiction to them. Due to overuse o…
View article: Efficacy Evaluation of Different Doses of Nitrgenous Fertilizers on the Growth and Yield of Maize (Zea mays)
Efficacy Evaluation of Different Doses of Nitrgenous Fertilizers on the Growth and Yield of Maize (Zea mays) Open
This study aimed to evaluate the effectiveness of various nitrogen fertilizer application strategies on maize growth and yield using a Randomized Complete Block Design (RCBD) at Descon Research Farms, Kasur during spring season 2024. Four …
View article: Auxin biodynamics and its integral role in enhancing plant resilience to environmental cues
Auxin biodynamics and its integral role in enhancing plant resilience to environmental cues Open
Auxins are essential plant hormones that regulate growth, development, and responses to environmental stressors. Plants frequently encounter challenges such as pests, diseases, high temperatures, drought, and salinity, which necessitate ad…
View article: Association of stress with BMI among medical students
Association of stress with BMI among medical students Open
Introduction: Medical education is considered as one of the most demanding courses. It brings with it a multitude of stressors which affects overall wellbeing of medical students.. Stress and BMI show association with each other. Stress ma…
View article: SCREENING OF RICE GERMPLASM AGAINST DROUGHT STRESS USING MORPHOLOGICAL PARAMETERS
SCREENING OF RICE GERMPLASM AGAINST DROUGHT STRESS USING MORPHOLOGICAL PARAMETERS Open
Oryza sativa L. is a staple diet for billions of people in the world. Different rice varieties' drought stress responses and their effects on both qualitative and quantitative variables. Rice is the second main exportable product of Pakist…
View article: Spatial transcriptome analysis reveals de novo regeneration of poplar roots
Spatial transcriptome analysis reveals de novo regeneration of poplar roots Open
Propagation through cuttings is a well-established and effective technique for plant multiplication. This study explores the regeneration of poplar roots using spatial transcriptomics to map a detailed developmental trajectory. Mapping of …
View article: Climate change induced salinization and quality deterioration of groundwater resources in Pakistan; Current scenario and future prospects
Climate change induced salinization and quality deterioration of groundwater resources in Pakistan; Current scenario and future prospects Open
Climate change has triggered various catastrophic events including groundwater salinization resulted in quality deterioration worldwide leading to the environmental degradation and posed threat to natural ecosystems. Pakistan is among the …
View article: Effectiveness of the Application of Drip Irrigation In Some Planting Media for Caisim (Barassica juncea L).
Effectiveness of the Application of Drip Irrigation In Some Planting Media for Caisim (Barassica juncea L). Open
Caisim plants are cultivated in highland areas. One of the methods to increase the productivity of caisim is by balancing the amount of water supplied and water needs of the plants. This can be done by applying drip irrigation where water …
View article: Integrating bio-organic fertilization increases twice-yearly cabbage crop production by modulating soil microbial community and biochemical properties in Northwest Plateau
Integrating bio-organic fertilization increases twice-yearly cabbage crop production by modulating soil microbial community and biochemical properties in Northwest Plateau Open
Decreasing the reliance on chemical fertilizers and integrating bio-organic fertilizers are effective strategies for enhancing soil quality, promoting sustainable agricultural development, and protecting the environment. However, their imp…
View article: Opportunities and Challenges in Advancing Plant Research with Single-cell Omics
Opportunities and Challenges in Advancing Plant Research with Single-cell Omics Open
Plants possess diverse cell types and intricate regulatory mechanisms to adapt to the ever-changing environment of nature. Various strategies have been employed to study cell types and their developmental progressions, including single-cel…
View article: An in-depth investigation of the microbiota and its virulence factors associated with severe udder cleft dermatitis lesions
An in-depth investigation of the microbiota and its virulence factors associated with severe udder cleft dermatitis lesions Open
Udder cleft dermatitis (UCD) is a skin condition affecting the anterior parts of the udder in dairy cattle. In the present study, we aimed to shed light on the microbiota in severe UCD lesions versus healthy udder skin by putting forward a…
View article: Ascension Vegetative Growth and Leaf Nutritional Status of ''Le- Conte'' Pear Trees Grown Under Desert Soil Conditions
Ascension Vegetative Growth and Leaf Nutritional Status of ''Le- Conte'' Pear Trees Grown Under Desert Soil Conditions Open
This research was carried out on 17-year-old "Le-Conte" pear trees that were grafted on Pyrus communis and were growing in loamy sand soil with drip irrigation over the two seasons of 2021 and 2022, to investigate the effects of two irriga…
View article: Antibiotic Efficacy of Commercially Available Antibiotics on Indigenous Microbes Isolated from Rotten Fruits
Antibiotic Efficacy of Commercially Available Antibiotics on Indigenous Microbes Isolated from Rotten Fruits Open
The human commonly consume fruits as food. Indigenous microbes are responsible for the spoilage of fruits. If bacteria spoil consumed fruit, they can cause infections in the human body that may lead to severe consequences. Some commerciall…
View article: Melatonin interaction with abscisic acid in the regulation of abiotic stress in Solanaceae family plants
Melatonin interaction with abscisic acid in the regulation of abiotic stress in Solanaceae family plants Open
Solanaceous vegetable crops are cultivated and consumed worldwide. However, they often confront diverse abiotic stresses that significantly impair their growth, yield, and overall quality. This review delves into melatonin and abscisic aci…
View article: Severe udder cleft dermatitis lesion transcriptomics points to an impaired skin barrier, defective wound repair and a dysregulated inflammatory response as key elements in the pathogenesis
Severe udder cleft dermatitis lesion transcriptomics points to an impaired skin barrier, defective wound repair and a dysregulated inflammatory response as key elements in the pathogenesis Open
This study is the first to investigate the transcriptomic changes occurring in severe udder cleft dermatitis lesions (UCD) in Holstein-Friesian cows. An examination of the gene expression levels in natural UCD lesions and healthy udder ski…
View article: Genome-wide analysis revealed the stepwise origin and functional diversification of HSDs from lower to higher plant species
Genome-wide analysis revealed the stepwise origin and functional diversification of HSDs from lower to higher plant species Open
Hydroxysteroid dehydrogenase (HSDs) is an oil-body sterol protein (steroleosin) with an NADP(H) binding domain that belongs to the short-chain dehydrogenase/reductase (SDR) superfamily. There are numerous studies on the characterization of…
View article: Tomato CYP94C1 terminates jasmonate signaling during fruit ripening by inactivating bioactive jasmonoyl-L-isoleucine
Tomato CYP94C1 terminates jasmonate signaling during fruit ripening by inactivating bioactive jasmonoyl-L-isoleucine Open
Ripe fruits are more susceptible to necrotrophic pathogens than unripe fruits. Although this phenomenon is widespread across different fruit species and results in substantial economic losses, the underlying mechanism is still poorly under…
View article: Cytokinin-inducible response regulator<i>SlRR6</i>controls plant height through gibberellin and auxin pathways in tomato
Cytokinin-inducible response regulator<i>SlRR6</i>controls plant height through gibberellin and auxin pathways in tomato Open
Plant height is a key agronomic trait regulated by several phytohormones such as gibberellins (GAs) and auxin. However, little is known about how cytokinin (CK) participates in this process. Here, we report that SlRR6, a type-A response re…
View article: Different leafy vegetable cropping systems regulate growth, photosynthesis, and PSII functioning in mono-cropped eggplant by altering chemical properties and upregulating the antioxidant system
Different leafy vegetable cropping systems regulate growth, photosynthesis, and PSII functioning in mono-cropped eggplant by altering chemical properties and upregulating the antioxidant system Open
Continuous cropping of eggplant threatened regional ecological sustainability by facilitating replanting problems under mono-cropping conditions. Therefore, alternative agronomic and management practices are required to improve crop produc…
View article: Evolution of antimicrobial cysteine-rich peptides in plants
Evolution of antimicrobial cysteine-rich peptides in plants Open
To defend against diverse groups of pathogens, plants produce cysteine-rich peptides (CRPs) with long-lasting broad-spectrum antimicrobial activity. We analyzed 240 plant genomes ranging from algae to eudicots and our comparative genomics …
View article: Recoloring tomato fruit by CRISPR/Cas9-mediated multiplex gene editing
Recoloring tomato fruit by CRISPR/Cas9-mediated multiplex gene editing Open
Fruit color is an important horticultural trait, which greatly affects consumer preferences. In tomato, fruit color is determined by the accumulation of different pigments, such as carotenoids in the pericarp and flavonoids in the peel, al…