Muhammad Jarkas
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View article: Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs)
Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs) Open
We analyzed actin cytoskeleton alterations during NET extrusion by neutrophil-like dHL-60 cells and human neutrophils in the absence of DNase1 containing serum to avoid chromatin degradation and microfilament disassembly. NET-formation by …
View article: Cardiac damage and tropism of severe acute respiratory syndrome coronavirus 2
Cardiac damage and tropism of severe acute respiratory syndrome coronavirus 2 Open
View article: Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy
Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy Open
Hypertrophic cardiomyopathy (HCM) is a complex myocardial disorder with no well-established disease-modifying therapy so far. Our study aimed to investigate how autophagy, oxidative stress, inflammation, stress signalling pathways, and apo…
View article: The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts
The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts Open
Oxidative stress is defined as an imbalance between the antioxidant defense system and the production of reactive oxygen species (ROS). At low levels, ROS are involved in the regulation of redox signaling for cell protection. However, upon…