Muhammad Shahid Iqbal
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View article: Watkins wheat landraces decode nitrogen-driven biomass trade-offs: GWAS exposes root-shoot dialectics and elite landraces for resilient agriculture
Watkins wheat landraces decode nitrogen-driven biomass trade-offs: GWAS exposes root-shoot dialectics and elite landraces for resilient agriculture Open
Introduction Nitrogen limitation is a critical abiotic stressor that disrupts the balance between plants and their environment, imposing trade-offs in biomass allocation that threaten crop productivity and food security. While modern breed…
View article: Epicardial Fat Thickness as a predictor of acute ischemic stroke at Rehman Medical Institute: A case-control study
Epicardial Fat Thickness as a predictor of acute ischemic stroke at Rehman Medical Institute: A case-control study Open
Introduction: Stroke is the leading cause of disability in the globe. There are numerous markers that can be employed to predict stroke risk. Epicardial Fat Thickness (EFT) is proposed to be one of them. Objective: To determine Epicardial …
View article: Artificial Intelligence and Early Detection of Breast, Lung, and Colon Cancer: A Narrative Review
Artificial Intelligence and Early Detection of Breast, Lung, and Colon Cancer: A Narrative Review Open
Artificial intelligence (AI) is revolutionizing early cancer detection by enhancing the sensitivity, efficiency, and precision of screening programs for breast, colorectal, and lung cancers. Deep learning algorithms, such as convolutional …
View article: Investigating Factors such as Frustration, Past Trauma, and High Aggression Levels that Contribute to Violent Conflicts in both Interpersonal and Social Contexts
Investigating Factors such as Frustration, Past Trauma, and High Aggression Levels that Contribute to Violent Conflicts in both Interpersonal and Social Contexts Open
This study explores the contribution of frustration, previous trauma, and aggression to violent conflict among university students, examining their psychological and structural determinants. Using a quantitative approach, a diverse sample …
View article: Gastrointestinal Symptoms and Liver Dysfunction in Children with Covid 19 Infection
Gastrointestinal Symptoms and Liver Dysfunction in Children with Covid 19 Infection Open
Background: Although, the primary organ of involvement are lungs in Coronavirus disease 2019 (COVID-19), however liver, and gastrointestinal (GI) involvement is being increasingly reported in the emerging data from various centers across t…
View article: Correction: Beliefs, awareness, use, and factors associated with herbal supplements usage among patients with chronic diseases–A cross-sectional insight from Alkharj, Saudi Arabia
Correction: Beliefs, awareness, use, and factors associated with herbal supplements usage among patients with chronic diseases–A cross-sectional insight from Alkharj, Saudi Arabia Open
[This corrects the article DOI: 10.1371/journal.pone.0295116.].
View article: In Response to Acute Oral Mucositis During Hypo-Fractionated Radiation in Squamous Cell Carcinoma of Oral Cavity
In Response to Acute Oral Mucositis During Hypo-Fractionated Radiation in Squamous Cell Carcinoma of Oral Cavity Open
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View article: Chest Tightness and Chronic Cough; Respiratory Symptoms Among Home-Based Textile Industry Workers
Chest Tightness and Chronic Cough; Respiratory Symptoms Among Home-Based Textile Industry Workers Open
Background: The textile industry, rooted in agriculture, stands as Pakistan's second-largest employer. Within this sector, home-based textile production plays a significant role, albeit largely unregulated and undocumented, resulting in su…
View article: The influence of pharmacist-led collaborative care on clinical outcomes in type 2 diabetes mellitus: a multicenter randomized control trial
The influence of pharmacist-led collaborative care on clinical outcomes in type 2 diabetes mellitus: a multicenter randomized control trial Open
Background Health care providers are mandated to deliver specialized care for the treatment and control of type 2 diabetes mellitus. In Malaysia, Diabetes Medication Therapy Adherence Clinics (DMTAC) in tertiary hospitals have designated p…
View article: Beliefs, awareness, use, and factors associated with herbal supplements usage among patients with chronic diseases–A cross-sectional insight from Alkharj, Saudi Arabia
Beliefs, awareness, use, and factors associated with herbal supplements usage among patients with chronic diseases–A cross-sectional insight from Alkharj, Saudi Arabia Open
Background Herbal supplements (HSs) are used to treat a variety of diseases and ailments. Individuals with chronic diseases are at a higher risk of having adverse events and drug interactions from the use of HSs. Aim This study determined …
View article: Point Prevalence Survey of Antimicrobial Use and Resistance during the COVID-19 Era among Hospitals in Saudi Arabia and the Implications
Point Prevalence Survey of Antimicrobial Use and Resistance during the COVID-19 Era among Hospitals in Saudi Arabia and the Implications Open
The inappropriate prescribing of antimicrobials increases antimicrobial resistance (AMR), which poses an appreciable threat to public health, increasing morbidity and mortality. Inappropriate antimicrobial prescribing includes their prescr…
View article: Tackling antimicrobial resistance in primary care facilities across Pakistan: Current challenges and implications for the future
Tackling antimicrobial resistance in primary care facilities across Pakistan: Current challenges and implications for the future Open
Antibiotics are gradually becoming less effective against bacteria worldwide, and this issue is of particular concern in economically-developing nations like Pakistan. We undertook a scoping review in order to review the literature on anti…
View article: Rights and Challenges: An Overview of Christian Minority in Lahore
Rights and Challenges: An Overview of Christian Minority in Lahore Open
The demography of Lahore presents a colorful picture of the anthology of multi-ethnic and multi-religious character with the overwhelming majority of Muslims and some other religious minorities in smaller number. This research paper is to …
View article: Parents’ Concerns, Behavior, Perception, and Hesitancy Regarding COVID-19 Vaccinations for Children in Central Saudi Arabia
Parents’ Concerns, Behavior, Perception, and Hesitancy Regarding COVID-19 Vaccinations for Children in Central Saudi Arabia Open
In Saudi Arabia, the Ministry of Health (MoH) has implemented strict rules to ensure COVID-19 vaccination uptake by the general public. However, there is hesitancy about COVID-19 vaccination among parents for their children worldwide. We a…
View article: Vaccine Hesitancy of COVID-19 among Parents for Their Children in Middle Eastern Countries—A Systematic Review
Vaccine Hesitancy of COVID-19 among Parents for Their Children in Middle Eastern Countries—A Systematic Review Open
The current systematic review presents COVID-19 vaccine hesitancy among parents for their children in Middle Eastern countries. Moreover, the vaccine acceptance rate of parents from the Middle East and the factors effecting the acceptance …
View article: Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic Open
Hajj pilgrimage is a large mass gathering global event that may facilitate the spread and emergence of various infectious diseases as well as antimicrobial resistance (AMR) in a local and global scenario. Planning and preparing for these p…
View article: The role and mechanism of action of microRNA-122 in cancer: Focusing on the liver
The role and mechanism of action of microRNA-122 in cancer: Focusing on the liver Open
microRNA-122 (miR-122) is a highly conserved microRNA that is predominantly expressed in the liver and plays a critical role in the regulation of liver metabolism. Recent studies have shown that miR-122 is involved in the pathogenesis of v…
View article: Prevalence of Gastroesophageal Reflux Disease among Diabetic Patients at Sharif Medical City Hospital, Lahore, Pakistan
Prevalence of Gastroesophageal Reflux Disease among Diabetic Patients at Sharif Medical City Hospital, Lahore, Pakistan Open
Background: Diabetes mellitus has been linked to various gastrointestinal motility disorders, including gastroesophageal reflux disease (GERD).This study aimed to determine the proportion of GERD in patients with diabetes mellitus.Method: …
View article: Knowledge, attitude, and perceptions about polycystic ovarian syndrome, and its determinants among Pakistani undergraduate students
Knowledge, attitude, and perceptions about polycystic ovarian syndrome, and its determinants among Pakistani undergraduate students Open
Objective The aim of the study was to evaluate knowledge, attitude, perception, and assess the determinants of polycystic ovarian syndrome (PCOS) among undergraduate students. Methods A cross-sectional study was conducted among female unde…
View article: CLINICAL OUTCOMES OF CEREBRAL VENOUS SINUS THROMBOSIS TREATED WITH RIVAROXABAN
CLINICAL OUTCOMES OF CEREBRAL VENOUS SINUS THROMBOSIS TREATED WITH RIVAROXABAN Open
Objective: Cerebral venous sinus thrombosis (CVST) is an uncommon subtype of stroke. Anticoagulation with heparin and warfarin is the recommended treatment. Direct Oral Anticoagulants (DOACs) have shown efficacy and safety in other thrombo…
View article: Dose optimization of vancomycin in obese patients: A systematic review
Dose optimization of vancomycin in obese patients: A systematic review Open
Background: Dose optimization of vancomycin plays a substantial role in drug pharmacokinetics because of the increased incidence of obesity worldwide. This systematic review was aimed to highlight the current dosing strategy of vancomycin …
View article: Exploring the intravenous narcotics and controlled drugs wastage and their financial impact: A descriptive single-center study
Exploring the intravenous narcotics and controlled drugs wastage and their financial impact: A descriptive single-center study Open
The overall wastage was less than 5% of the total consumption, however, midazolam was observed to have the highest wastage. Shifting to prefilled syringes supplied by pharmacies, making protocols, and safely pooling costly drugs could resu…
View article: Impact of Positive Culture Reports of E. coli or MSSA on De-Escalation of Antibiotic Use in a Teaching Hospital in Pakistan and the Implications
Impact of Positive Culture Reports of E. coli or MSSA on De-Escalation of Antibiotic Use in a Teaching Hospital in Pakistan and the Implications Open
Culture sensitivity reports helped in the de-escalation of antimicrobial therapy, reducing the prescribing of especially broad-spectrum antibiotics. Consequently, it is recommended that local hospital guidelines be developed based on local…
View article: Point Prevalence Survey of Antimicrobial Use during the COVID-19 Pandemic among Different Hospitals in Pakistan: Findings and Implications
Point Prevalence Survey of Antimicrobial Use during the COVID-19 Pandemic among Different Hospitals in Pakistan: Findings and Implications Open
The COVID-19 pandemic has significantly influenced antimicrobial use in hospitals, raising concerns regarding increased antimicrobial resistance (AMR) through their overuse. The objective of this study was to assess patterns of antimicrobi…
View article: Development of the Amorphous Solid Dispersion of Curcumin: A Rational Selection of Polymers for Enhanced Solubility and Dissolution
Development of the Amorphous Solid Dispersion of Curcumin: A Rational Selection of Polymers for Enhanced Solubility and Dissolution Open
The goal of this investigation was to determine the effectiveness of hydrophilic polymers in preparing a solid dispersion to enhance the solubility and dissolution of poorly water-soluble drugs, such as curcumin. In order to prepare the so…
View article: VALPROATE INDUCED HYPERAMMONEMIC ENCEPHALOPATHY
VALPROATE INDUCED HYPERAMMONEMIC ENCEPHALOPATHY Open
Valproate is a commonly prescribed anticonvulsant drug. It has a potential to cause hyperammonemia even in the presence of normal liver function tests. This hyperammonemic state can lead to encephalopathy referred as Valproate induced hype…
View article: Evaluation of knowledge and barriers of influenza vaccine uptake among university students in Saudi Arabia; a cross-sectional analysis
Evaluation of knowledge and barriers of influenza vaccine uptake among university students in Saudi Arabia; a cross-sectional analysis Open
Background Influenza vaccine hesitancy is a significant threat to global maneuvers for reducing the burden of seasonal and pandemic influenza. This study estimated the vaccine uptake, barriers, and willingness for influenza vaccines among …
View article: Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review
Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review Open
Background: β-lactams remain the cornerstone of the empirical therapy to treat various bacterial infections. This systematic review aimed to analyze the data describing the dosing regimen of β-lactams. Methods: Systematic scientific and gr…