Muhammad Sajjad
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View article: Nucleoredoxin 1 in Wheat: Genomic Analysis and Demonstration of Its Role in Redox Homeostasis and Stress Resilience
Nucleoredoxin 1 in Wheat: Genomic Analysis and Demonstration of Its Role in Redox Homeostasis and Stress Resilience Open
Nucleoredoxin 1 (NRX1), a member of the redoxin superfamily, plays a critical role in maintaining redox homeostasis and enhancing stress tolerance in plants. We employed integrated in silico analyses and CRISPR‐Cas9‐based genome editing to…
View article: Role of Intracranial Aneurysm Location in Determining Optimal Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Role of Intracranial Aneurysm Location in Determining Optimal Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
View article: Evaluating Long-Term Neurological and Functional Recovery in Acute Traumatic Spinal Cord Injury: A Prospective Cohort Study
Evaluating Long-Term Neurological and Functional Recovery in Acute Traumatic Spinal Cord Injury: A Prospective Cohort Study Open
Background Traumatic spinal cord injuries often result in significant disability and impact patients' functional independence and quality of life. Objective This study aims to evaluate neurological recovery, independence in daily activitie…
View article: Synergistic Photothermal Antibacterial Effects of Silver-Coated Upconversion Nanoparticles: Experimental Insights and DFT Calculations
Synergistic Photothermal Antibacterial Effects of Silver-Coated Upconversion Nanoparticles: Experimental Insights and DFT Calculations Open
The rise of antibiotic-resistant bacterial infections presents a significant global health challenge, contributing to higher mortality rates and prolonged hospitalizations. A promising solution is the development of localized hyperthermia …
View article: A genome-wide analysis of ascorbate oxidase gene family and hormonal activity in mango exposed to enhanced UV-B radiation
A genome-wide analysis of ascorbate oxidase gene family and hormonal activity in mango exposed to enhanced UV-B radiation Open
Background Ascorbate oxidase (AO), an apoplastic enzyme from the multi-copper oxidase family, is vital in maintaining redox homeostasis, particularly under environmental stress conditions like enhanced UV-B radiation. Our research group ha…
View article: Ensemble Deep Learning and LLM-Assisted Reporting for Automated Skin Lesion Diagnosis
Ensemble Deep Learning and LLM-Assisted Reporting for Automated Skin Lesion Diagnosis Open
Cutaneous malignancies demand early detection for favorable outcomes, yet current diagnostics suffer from inter-observer variability and access disparities. While AI shows promise, existing dermatological systems are limited by homogeneous…
View article: Impact of Irrigation Techniques on Water-Use Efficiency, Economic Returns, and Productivity of Rice
Impact of Irrigation Techniques on Water-Use Efficiency, Economic Returns, and Productivity of Rice Open
The growing global population and water scarcities are putting pressure on researchers to develop new techniques for food production that require less water. In agriculture, sustainable irrigation methods considerably improve water-use eff…
View article: Mental Health Disparities among Orphaned and Non-Orphaned Adolescents: A Cross-Sectional Study
Mental Health Disparities among Orphaned and Non-Orphaned Adolescents: A Cross-Sectional Study Open
Introduction: Approximately 153 million children worldwide face orphanhood, with 17.8 million losing both of their parents. Parental carelessness raises the likelihood of stress, anxiety, and depression and can cause severe psychological s…
View article: Association Between Vitamin D Levels and Infective Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)
Association Between Vitamin D Levels and Infective Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Open
Background: Chronic obstructive pulmonary disease (COPD) is a major global health burden, with exacerbations significantly worsening patient outcomes and increasing healthcare utilization. Despite abundant sunlight in many regions, vitamin…
View article: The Role of Gut Microbiome in Managing CVD, Hypertension, and Obesity: Evidence from a Clinical Trial
The Role of Gut Microbiome in Managing CVD, Hypertension, and Obesity: Evidence from a Clinical Trial Open
Background: Heart diseases, hypertension, and obesity are major health problems causing illness and death globally. New research shows a strong connection between gut bacteria and overall health. This study looks at how changing gut bacter…
View article: Estimation of Economic Efficiency of Maize Growers in Northern Khyber Pakhtunkhwa, Pakistan
Estimation of Economic Efficiency of Maize Growers in Northern Khyber Pakhtunkhwa, Pakistan Open
This study evaluates the economic efficiency of maize growers in Northern Khyber Pakhtunkhwa, Pakistan, with a focus on the two districts of Swat and Buner. A total of 100 maize farmers (50 from each district) were selected using a multi-s…
View article: A rare case of betel nut-associated oral squamous cell carcinoma in the United States: a case study
A rare case of betel nut-associated oral squamous cell carcinoma in the United States: a case study Open
View article: Numerical Investigations on Heat and Mass Transport in Passive Solar Evaporators with Non-Uniform Surface Temperature
Numerical Investigations on Heat and Mass Transport in Passive Solar Evaporators with Non-Uniform Surface Temperature Open
Passive solar desalination with no discharge promises great potential for sustainable desalination. Herein, we provide a comprehensive modelling scheme for the investigation of coupled heat and mass transport in passive desalination device…
View article: ASSESSING THE IMPACT OF PHARMACOGENOMICS ON DRUG PRESCRIBING PATTERNS IN CHRONIC DISEASE MANAGEMENT
ASSESSING THE IMPACT OF PHARMACOGENOMICS ON DRUG PRESCRIBING PATTERNS IN CHRONIC DISEASE MANAGEMENT Open
Background: Pharmacogenomics has emerged as a useful tool in tailoring drug therapies, particularly in managing chronic diseases, where safety and efficacy over the long term are critical. Objective: This study aimed to establish pharmacog…
View article: The Science of Satiety: A Review of How Nutrition Influences Appetite and Weight Control
The Science of Satiety: A Review of How Nutrition Influences Appetite and Weight Control Open
Background: Satiety, the physiological response controlling hunger, is an essential component of weight control. Obesity and weight issues are international health problems linked to inadequate dietary intake and a lack of physical activit…
View article: The Role of Functional Foods in Chronic Disease Prevention: A Clinical Trial Investigating Nutritional Interventions in Type 2 Diabetes Management
The Role of Functional Foods in Chronic Disease Prevention: A Clinical Trial Investigating Nutritional Interventions in Type 2 Diabetes Management Open
Background: Type 2 Diabetes (T2DM) is a metabolic disease due to insulin resistance associated with chronic inflammation. While pharmacological treatment remains primary, functional foods rich in bioactive substances such as polyphenols, o…
View article: Nanosponge-Encapsulated Polyoxometalates: Unveiling the Multi-Faceted Potential Against Cancers and Metastases Through Comprehensive Preparation, Characterization, and Computational Exploration
Nanosponge-Encapsulated Polyoxometalates: Unveiling the Multi-Faceted Potential Against Cancers and Metastases Through Comprehensive Preparation, Characterization, and Computational Exploration Open
Background/Objectives: This study examined the fabrication and characterization of nanosponges (NS) laden with polyoxometalates (TiW11Co) with the intention of targeting malignancy. Methods: By employing the emulsion solvent diffusion tech…
View article: Overexpression of <i>TaSnRK2.9s</i> Improves Plant Growth and Development in Rice (<i>Oryza sativa</i> L.)
Overexpression of <i>TaSnRK2.9s</i> Improves Plant Growth and Development in Rice (<i>Oryza sativa</i> L.) Open
Sucrose nonfermenting‐1 related protein kinase (SnRK2) is an important family of stress signalling genes related to nutrient utilisation, metabolic regulations and responsive to external stressors. In this work, all three copies of TaSnRK2…
View article: Nanosponges-Encapsulated Polyoxometalates; Unveiling Multi-Faceted Potential Against Cancer and Metastasis Through Comprehensive Preparation, Characterization, and Computational Exploration
Nanosponges-Encapsulated Polyoxometalates; Unveiling Multi-Faceted Potential Against Cancer and Metastasis Through Comprehensive Preparation, Characterization, and Computational Exploration Open
The study examined the fabrication and characterization of nanosponges (NS) laden with polyoxometalates (TiW11Co) with the intention of targeting malignancy. By employing the emulsion solvent diffusion technique, TiW11Co-NS were generated …
View article: Comparative evaluation of Acheta domesticus and Hermetia illucens as alternative protein sources for the growth, health, and meat quality of the broiler
Comparative evaluation of Acheta domesticus and Hermetia illucens as alternative protein sources for the growth, health, and meat quality of the broiler Open
Introduction Insects are receiving increasing attention due to their potential to enhance farming efficiency and sustainability, mitigate vast quantities of bio-waste, and improve animal performance. It is hypothesized that replacing soybe…
View article: The Impact of Split Nitrogen Fertilizer Applications on the Productivity and Nitrogen Use Efficiency of Rice
The Impact of Split Nitrogen Fertilizer Applications on the Productivity and Nitrogen Use Efficiency of Rice Open
The application of nitrogenous fertilizer in reduced (“split”) doses of its total is suggested as a means to increase nitrogen use efficiency and rice productivity whilst reducing its environmental impact. Field trials conducted in 2022 an…
View article: Glutathione and Ascorbic Acid Accumulation in Mango Pulp Under Enhanced UV-B Based on Transcriptome
Glutathione and Ascorbic Acid Accumulation in Mango Pulp Under Enhanced UV-B Based on Transcriptome Open
Mango (Mangifera indica), a nutritionally rich tropical fruit, is significantly impacted by UV-B radiation, which induces oxidative stress and disrupts physiological processes. This study aimed to investigate mango pulp’s molecular and bio…
View article: Diagnostic Accuracy of Beta-D-Glucan and Galactomannan as Fungal Markers in the Detection of Positive Fungal Cultures among Immunocompromised Patients
Diagnostic Accuracy of Beta-D-Glucan and Galactomannan as Fungal Markers in the Detection of Positive Fungal Cultures among Immunocompromised Patients Open
As fungal infections pose a significant threat to immunocompromised patients, necessitating timely and accurate diagnostic approaches for effective management, non-invasive diagnostic markers are direly needed to detect the presence of fun…
View article: Use of Periplaneta americana as a Soybean Meal Substitute: A Step towards Sustainable Transformative Poultry Feeds
Use of Periplaneta americana as a Soybean Meal Substitute: A Step towards Sustainable Transformative Poultry Feeds Open
Insects are becoming increasingly popular as a sustainable and nutritious alternative protein source in poultry feeds, due to their high protein content, low environmental impact, and efficient feed conversion rates. Using insect-based fee…
View article: Insect Larvae as an Alternate Protein Source in Poultry Feed Improve the Performance and Meat Quality of Broilers
Insect Larvae as an Alternate Protein Source in Poultry Feed Improve the Performance and Meat Quality of Broilers Open
The primary challenge facing the global animal industry is the scarcity of protein feed resources. Various insects are gaining prominence as innovative feed sources due to their economic, environmentally friendly, and nutritious attributes…
View article: Transcriptomic Analysis Reveals Dynamic Changes in Glutathione and Ascorbic Acid Content in Mango Pulp across Growth and Development Stages
Transcriptomic Analysis Reveals Dynamic Changes in Glutathione and Ascorbic Acid Content in Mango Pulp across Growth and Development Stages Open
Mango (Mangifera indica) is a highly valuable horticultural crop known for its quality and productivity. This study investigates the dynamic changes in physicochemical properties and glutathione and ascorbic acid metabolic pathways in mang…
View article: Diversity of medicinal flora and traditional knowledge of Muzaffargarh District Punjab Province, Pakistan
Diversity of medicinal flora and traditional knowledge of Muzaffargarh District Punjab Province, Pakistan Open
Background: Ethnomedicine is an important part of different cultures across the globe. It has a central role in providing new medicinal plants to phytochemical exploration and effective drug discoveries for centuries. Methods: Ethnobotanic…
View article: Effects of Foliar Ca and Mg Nutrients on the Respiration of ‘Feizixiao’ Litchi Pulp and Identification of Differential Expression Genes Associated with Respiration
Effects of Foliar Ca and Mg Nutrients on the Respiration of ‘Feizixiao’ Litchi Pulp and Identification of Differential Expression Genes Associated with Respiration Open
The ‘Feizixiao’ litchi cultivar, predominantly grown in Hainan Province, faces the issue of “sugar receding” during fruit ripening. The application of mixed foliar nutrients containing calcium and magnesium (Ca+Mg) during the fruit pericar…
View article: Polyploidization Impact on Plant Architecture of Watermelon (Citrullus lanatus)
Polyploidization Impact on Plant Architecture of Watermelon (Citrullus lanatus) Open
Plant architecture includes traits such as plant height, stem diameter, and branching pattern, which have significant impacts on yield and fruit quality. Polyploidization can bring changes in plant architectural traits in different crops a…
View article: Sharing the ecological knowledge of plants used in handicrafts as a survival strategy of rural communities of Dera Ghazi Khan district, Pakistan
Sharing the ecological knowledge of plants used in handicrafts as a survival strategy of rural communities of Dera Ghazi Khan district, Pakistan Open
Background: Craftwork is one of the vital components of phyto-culture worldwide. It offers a livelihood to marginalized communities in the rapidly changing environmental conditions with the preservation of cultural diversity. This study ai…