Explanipedia

AI-assisted CT assessment of tricuspid regurgitation severity correlates with echocardiographic grading Open

Max Potratz, Lamis El Harake, Akhil Narang, Muhammed Gerçek, Tanja K. Rudolph , et al. · 2025

Background Accurate assessment of tricuspid regurgitation (TR) severity is crucial for guiding transcatheter tricuspid valve intervention (TTVI). While echocardiography is the standard, it can be operator-dependent and have limitations in …

Characterization of Patients Unsuited for Transcatheter Mitral Valve Interventions Open

CA Clara, Hannah Eustergerling, Johanna Isabella Pepping, Vanessa Trenkpohl, Kai Friedrichs , et al. · 2025

Background/Objectives: The objective of this study was to characterize echocardiographic characteristics comparing patients accepted or deemed unsuitable for transcatheter mitral valve interventions. Methods: We performed a retrospective a…

Impact of age on outcomes after transcatheter tricuspid valve edge-to-edge repair: insights from EuroTR Open

Julia Novotny, Lukas Stolz, Karl‐Patrik Kresoja, Jennifer von Stein, Vera Fortmeier , et al. · 2025

Objective Age stratified data regarding symptomatic and survival outcome of patients undergoing transcatheter tricuspid valve edge-to-edge repair (T-TEER) for severe tricuspid regurgitation (TR) are scarce. Aim of this study was to evaluat…

Residual SYNTAX score and outcomes after TAVR+PCI versus SAVR+CABG: a propensity-matched, gender-based comparison Open

Max Potratz, Vera Fortmeier, Katharina Höflsauer, Muhammed Gerçek, Isabel Horn , et al. · 2025

Background Aortic stenosis (AS) and coronary artery disease (CAD) frequently coexist, requiring careful revascularisation strategy consideration. While surgical aortic valve replacement (SAVR) plus coronary artery bypass grafting (CABG) is…

Predictability of post-delivery mitral regurgitation with a new generation transcatheter edge-to-edge device Open

Katharina Hellhammer, Florian Schindhelm, Tobias Geisler, Isabela Kast, Andreas Goldschmied , et al. · 2025

Background Ensuring stable MR reduction post-device release is critical for procedural success, as applying a second device may not always be feasible. Incidence of change in residual MR and influencing factors using the PASCAL Precision s…

Early Outcomes of Real-World Transcatheter Tricuspid Valve Replacement Open

Domenico Angellotti, Isabel Mattig, Daryoush Samim, Björn Goebel, Charlotte Jantsch , et al. · 2025

TR elimination following TTVR in a real-world setting was associated with significant symptom and end-organ functional improvement. Patients with massive or torrential TR were more likely to experience functional improvement. Pre-existing …

Prognostic value of NT‐proBNP in patients with primary mitral regurgitation undergoing transcatheter edge‐to‐edge repair Open

Philipp von Stein, Jessica Weimann, Roman Pfister, Sebastian Ludwig, Benedikt Koell , et al. · 2025

Aims The prognostic value of N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) in patients undergoing mitral valve transcatheter edge‐to‐edge repair (M‐TEER) for primary mitral regurgitation (PMR) is unclear. This study assessed the as…

Employment of artificial intelligence for an unbiased evaluation regarding the recovery of right ventricular function after mitral valve transcatheter edge‐to‐edge repair Open

Vera Fortmeier, Amelie Hesse, Teresa Trenkwalder, Márton Tokodi, Attila Kovács , et al. · 2025

Aims Long‐standing severe mitral regurgitation (MR) leads to left atrial (LA) enlargement, elevated pulmonary artery pressures, and ultimately right heart failure. While mitral valve transcatheter edge‐to‐edge repair (M‐TEER) alleviates le…

71579 | Assessment of the GLIDE Score for Prediction of Mild Tricuspid Regurgitation Following Tricuspid Transcatheter Edge-to-Edge Repair Open

Felix Rudolph, Akhil Narang, Maria Körber, Kai Friedrichs, Johannes Kirchner , et al. · 2025

72217 | Automated CT-Derived Annular Displacement Predicts Early RV Strain Changes Independently of Baseline Right Ventricular Ejection Fraction After Transcatheter Tricuspid Valve Replacement Open

Max Potratz, Lamis ElHarake, Muhammed Gerçek, Felix Rudolph, Johannes Kirchner , et al. · 2025

71119 | The GLIDE Score Predicts Procedural Success Not Only in Patients Undergoing Transcatheter Edge-to-Edge Repair but Also Tricuspid Annuloplasty Open

J. Althoff, Muhammed Gerçek, Dennis Mehrkens, Felix Rudolph, Thorsten Gietzen , et al. · 2025

Cardiac implantable electronic device carriers undergoing transcatheter tricuspid valve annuloplasty: real-world insights Open

Jan Wrobel, Johannes Kirchner, Kai Friedrichs, Thorsten Gietzen, J. Althoff , et al. · 2025

Assessment of the GLIDE Score for Prediction of Mild Tricuspid Regurgitation following Tricuspid Transcatheter Edge-to-Edge Repair Open

Felix Rudolph, Akhil Narang, Maria Isabel Körber, Kai Friedrichs, Johannes Kirchner , et al. · 2025

The GLIDE Score is a valuable tool for predicting postprocedural TR severity in T-TEER patients, guiding patient selection and refining treatment strategies.

Impact of impaired renal function on kinetics of high-sensitive cardiac troponin following cardiac surgery Open

Felix Rudolph, Marcus-André Deutsch, Kai Friedrichs, André Renner, Werner Scholtz , et al. · 2025

Background Impaired renal function can increase cardiac troponin levels due to reduced elimination, potentially affecting its diagnostic utility. Limited data exist on high-sensitivity cardiac troponin I (hs-cTnI) kinetics after cardiac su…

Simplified Outcome Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention by Survival Tree-Based Modelling Open

Vera Fortmeier, Mark Lachmann, Lukas Stolz, Jennifer von Stein, Karl‐Philipp Rommel , et al. · 2025

Correction: The influence of lipoprotein(a) on aortic valve calcification in patients undergoing transcatheter aortic valve replacement Open

Johanna Bormann, Felix Rudolph, Max J. Miller, Sara Waezsada, Johannes Kirchner , et al. · 2025

Cardiac magnetic resonance vs 3D echocardiography in patients with severe tricuspid regurgitation: Comparison pre- and post-Interventional repair Open

Roberto Sarnari, Minyoung Kim, Volker Rudolph, Muhammed Gerçek, James A. Thomas , et al. · 2025

The influence of lipoprotein(a) on aortic valve calcification in patients undergoing transcatheter aortic valve replacement Open

Johanna Bormann, Felix Rudolph, Max J. Miller, Sara Waezsada, Johannes Kirchner , et al. · 2024

Background Elevated levels of lipoprotein(a) (Lp[a]) have been recognized as substantial risk factors for cardiovascular disease and aortic stenosis (AS). However, the specific role of Lp(a) in promoting aortic valve calcification (AVC) an…

The prognostic value of the Dandel's index in patients undergoing tricuspid transcatheter edge‐to‐edge repair Open

Mohammad Kassar, Nicolas Brugger, Lukas Stolz, Muhammed Gerçek, Vera Fortmeier , et al. · 2024

Aims Conventional parameters of right ventricular (RV) function are load‐dependent and therefore do not accurately reflect contractility in patients with relevant tricuspid regurgitation (TR). RV adaptability to load has been characterized…

Impact of right ventricular function on cardiopulmonary exercise capacity in mitral regurgitation patients undergoing transcatheter mitral valve intervention Open

Muhammed Gerçek, Maria Ivannikova, Mustafa Gerçek, Maximilian Moersdorf, Johannes Kirchner , et al. · 2024

SEC is significantly increased in MR patients undergoing TMVI, reflecting an improvement, especially regarding daily life activities. This may be related to TMVIś beneficial effect on right ventricular remodeling.

Impact of Pulmonary Hypertension on Outcomes After Transcatheter Tricuspid Valve Edge-to-Edge Repair Open

Lukas Stolz, Karl‐Patrik Kresoja, Jennifer von Stein, Vera Fortmeier, Benedikt Koell , et al. · 2024

PH is an important outcome predictor in patients undergoing T-TEER for relevant TR. In contrast to previous studies, no significant differences were observed for patients with precapillary and postcapillary PH in terms of survival free fro…

Exercise testing in patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention Open

Muhammed Gerçek, Maria Ivannikova, Arseniy Goncharov, Mustafa Gerçek, Maximilian Mörsdorf , et al. · 2024

Background Transcatheter tricuspid valve intervention (TTVI) has shown promising results with persistent reduction of tricuspid regurgitation (TR) and improvements in functional class and quality of life (QOL). Objectives To analyze the im…

Perioperative outcome of left atrial appendage amputation in coronary artery bypass grafting Open

Mustafa Gerçek, Tomislav Skuljevic, Jochen Börgermann, Jan Gummert, Muhammed Gerçek · 2024

Background Left atrial appendage (LAA) amputation performed alongside cardiac surgery has become an increasingly established procedure to reduce stroke risk in patients with atrial fibrillation. As the recommendation levels for LAA amputat…

Early Outcomes of Two Large Mitral Valve Transcatheter Edge-to-Edge Repair Devices—A Propensity Score Matched Multicenter Comparison Open

Philipp von Stein, Hendrik Wienemann, Jennifer von Stein, Atsushi Sugiura, Tetsu Tanaka , et al. · 2024

Background/Objectives: Previous trials reported comparable results with PASCAL and earlier MitraClip generations. Limited comparative data exist for more contemporary MitraClip generations, particularly the large MitraClip XT(R/W). We aime…

Postoperative Atrial Fibrillation Prediction by Left Atrial Size in Coronary Artery Bypass Grafting and Five-Year Survival Outcome Open

Mustafa Gerçek, Jochen Börgermann, Jan Gummert, Muhammed Gerçek · 2024

Background: Postoperative Atrial Fibrillation (POAF) is a common complication in cardiac surgery. Despite its multifactorial origin, the left atrial (LA) size is closely linked to POAF, raising the question of a valid cut-off value and its…

GLIDE Score Open

Muhammed Gerçek, Akhil Narang, Maria Isabel Körber, Kai Friedrichs, Jyothy Puthumana , et al. · 2024

Tricuspid valve transcatheter edge-to-edge repair (T-TEER) is the most widely used transcatheter therapy to treat patients with tricuspid regurgitation (TR). The aim of this study was to develop a simple anatomical score to predict procedu…

Performance of Transcatheter Direct Annuloplasty in Patients With Atrial and Nonatrial Functional Tricuspid Regurgitation Open

Jennifer von Stein, Philipp von Stein, Thorsten Gietzen, J. Althoff, Caroline Hasse , et al. · 2024

Direct TTVA effectively reduces TR in both A-FTR, which is a strong and independent predictor of achieving TR ≤II, and NA-FTR. Even though NA-FTR showed more RV remodeling at baseline, both phenotypes experienced similar symptomatic improv…

Mortality after cardiac resynchronization therapy or right ventricular pacing in transcatheter aortic valve replacement recipients Open

Johannes Kirchner, Muhammed Gerçek, Vanessa Sciacca, Jan‐Christian Reil, Denise Guckel , et al. · 2024

Background Permanent pacemaker implantation (PMI) is associated with increased morbidity after transcatheter aortic valve replacement (TAVR). Cardiac resynchronization-therapy (CRT) is recommended for patients if left ventricular ejection …

Congestion patterns in severe tricuspid regurgitation and transcatheter treatment: Insights from a multicentre registry Open

Karl‐Philipp Rommel, Guillaume Bonnet, Vera Fortmeier, Lukas Stolz, Anne Rebecca Schöber , et al. · 2024

Aims While invasively determined congestion holds mechanistic and prognostic significance in acute heart failure (HF), its role in patients with tricuspid regurgitation (TR)‐related right‐ heart failure (HF) undergoing transcatheter tricus…

Sleep apnea in patients undergoing coronary artery bypass grafting: Impact on perioperative outcomes Open

Kassar Farha, Mustafa Gerçek, Muhammed Gerçek, Johannes Mischlinger, Volker Rudolph , et al. · 2024

Summary Sleep‐disordered breathing is common in patients with coronary artery disease undergoing coronary artery bypass grafting. Sleep‐disordered breathing is associated with increased perioperative morbidity, arrhythmias (e.g. atrial fib…

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