Mui Heng Goh
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View article: Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women
Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women Open
Background: Breast cancer polygenic risk scores (PRS) and traditional risk models (e.g., the Gail model [Gail]) are known to contribute largely independent information, but it is unclear how the overlap varies by ancestry, age, disease typ…
View article: Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries
Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries Open
Background Breast cancer is multifactorial. Focusing on limited risk factors may miss high-risk individuals. Methods We assessed the performance and overlap of various risk factors in identifying high-risk individuals for invasive breast c…
View article: Overlap of High-Risk Individuals Predicted by Family History, Genetic and Non-Genetic Breast Cancer Risk Prediction Models: An Analysis of 180,398 Women Across European and Asian Ancestry Populations
Overlap of High-Risk Individuals Predicted by Family History, Genetic and Non-Genetic Breast Cancer Risk Prediction Models: An Analysis of 180,398 Women Across European and Asian Ancestry Populations Open
View article: Evaluating Treatment Outcomes in Women with Node-Negative T1 Breast Cancers
Evaluating Treatment Outcomes in Women with Node-Negative T1 Breast Cancers Open
Background: With greater awareness and increased screening, cancers are increasingly being diagnosed at stage I. Women with these small node-negative tumours have excellent survival prospects after surgery, but many women, especially those…
View article: The therapeutic dilemma of idiopathic granulomatous mastitis
The therapeutic dilemma of idiopathic granulomatous mastitis Open
Introduction: Idiopathic granulomatous mastitis (IGM) is a rare, benign, chronic breast condition that can cause repeated abscesses or mass formation in bilateral breasts. The condition can severely impact the quality of life of affected w…
View article: Understanding the Psychosocial Needs of Women who Present with Advanced Breast Cancer
Understanding the Psychosocial Needs of Women who Present with Advanced Breast Cancer Open
Introduction: Advanced breast cancer (ABC) remains common in Singapore. In 2019, 22.1% of breast cancer patients presented with ABC in our institution. Despite increasing affluence and the advent of national mammographic screening, the inc…
View article: The Changing Epidemiology of Serious Trauma in the Elderly Population: An Increasing Concern of a Tertiary Hospital in Singapore
The Changing Epidemiology of Serious Trauma in the Elderly Population: An Increasing Concern of a Tertiary Hospital in Singapore Open
Introduction: Although trauma is often seen in the young, there is a recent shift in this trend as more elderly patients are hospitalised for traumatic injuries. This study examined serious trauma in young and elderly patients and hypothes…
View article: The Role of Metastasectomy in Women with Solitary Metastatic Breast Cancer Recurrence
The Role of Metastasectomy in Women with Solitary Metastatic Breast Cancer Recurrence Open
Background: Complete resection of solitary metastasis can render a woman disease-free, raising the possibility that curative treatment is still possible even in metastatic breast cancer. However, there is no conclusive data in support of t…
View article: Erratum to: Occult pneumothorax in blunt trauma: is there a need for tube thoracostomy?
Erratum to: Occult pneumothorax in blunt trauma: is there a need for tube thoracostomy? Open