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View article: Bioscaffold guidance drives liver periportal area tubulogenesis in hIPSC organoids
Bioscaffold guidance drives liver periportal area tubulogenesis in hIPSC organoids Open
Recapitulating the liver periportal area in vitro remains a major challenge due to its complex cellular composition and the coordinated development of both ductal and endothelial networks. Most existing bile duct organoid models fail to re…
View article: The Potential of Using Chromium Plating to Reduce Ingress of Hydrogen Isotopes in CANDU Reactor Rolled Joints
The Potential of Using Chromium Plating to Reduce Ingress of Hydrogen Isotopes in CANDU Reactor Rolled Joints Open
Some recent measurements of hydrogen isotope concentrations in zirconium pressure tubes at the rolled joints in CANDU reactors have been surprisingly high reaching equivalent hydrogen values above the current license limit of 120 μg H/g Zr…
View article: Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells
Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells Open
Chromatin architecture is critical in determining nuclear mechanics. Most studies focus on the mechanical rigidity conferred by chromatin condensation from densely packed heterochromatin, but less is known on how transient chromatin decomp…
View article: Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells
Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells Open
Chromatin architecture is critical in determining nuclear mechanics. Most studies focus on the mechanical rigidity conferred by chromatin compaction from densely packed heterochromatin, but less is known on how transient changes in chromat…
View article: Regulation of intercellular viscosity by E-cadherin-dependent phosphorylation of EGFR in collective cell migration
Regulation of intercellular viscosity by E-cadherin-dependent phosphorylation of EGFR in collective cell migration Open
Collective cell migration is crucial in various physiological processes, including wound healing, morphogenesis, and cancer metastasis. Adherens Junctions (AJs) play a pivotal role in regulating cell cohesion and migration dynamics during …
View article: Atomic force microscopy in the characterization and clinical evaluation of neurological disorders: current and emerging technologies
Atomic force microscopy in the characterization and clinical evaluation of neurological disorders: current and emerging technologies Open
This review examines the significant role of Atomic Force Microscopy (AFM) in neurobiological research and its emerging clinical applications in diagnosing neurological disorders and central nervous system (CNS) tumours. AFM, known for its…
View article: Spa2 remodels ADP-actin via molecular condensation under glucose starvation
Spa2 remodels ADP-actin via molecular condensation under glucose starvation Open
View article: Correction to “Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment”
Correction to “Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment” Open
ADVERTISEMENT RETURN TO ARTICLES ASAPPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment"C…
View article: Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment
Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment Open
Transplanting human induced pluripotent stem cells (iPSCs)-derived spinal cord progenitor cells (SCPCs) is a promising approach to treat spinal cord injuries. However, stem cell therapies face challenges in cell survival, cell localization…
View article: A Plasmonic Supramolecular Nanohybrid as a Contrast Agent for Site‐Selective Computed Tomography Imaging of Tumor
A Plasmonic Supramolecular Nanohybrid as a Contrast Agent for Site‐Selective Computed Tomography Imaging of Tumor Open
Design of organic–inorganic hybrids by anchoring of plasmonic materials such as gold nanoparticles (AuNPs) on self‐assembled organic substrates is useful but challenging. Herein, in situ anchoring of plasmonic nanoparticles on the surface …
View article: Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing
Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing Open
View article: Skin models for cutaneous melioidosis reveal <i>Burkholderia</i> infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment
Skin models for cutaneous melioidosis reveal <i>Burkholderia</i> infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment Open
ABSTRACTMelioidosis is a serious infectious disease endemic in Southeast Asia, Northern Australia and has been increasingly reported in other tropical and subtropical regions in the world. Percutaneous inoculation through cuts and w…
View article: Skin models for cutaneous melioidosis reveal <i>Burkholderia</i> infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment
Skin models for cutaneous melioidosis reveal <i>Burkholderia</i> infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment Open
Melioidosis is a serious infectious disease endemic in Southeast Asia, Northern Australia and has been increasingly reported in other tropical and subtropical regions in the world. Percutaneous inoculation through cuts and wounds on the sk…
View article: Thermal‐Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy
Thermal‐Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy Open
Bacterial infections remain a leading threat to global health because of the misuse of antibiotics and the rise in drug‐resistant pathogens. Although several strategies such as photothermal therapy and magneto‐thermal therapy can suppress …
View article: Potassium channel dysfunction in human neuronal models of Angelman syndrome
Potassium channel dysfunction in human neuronal models of Angelman syndrome Open
Hyperexcitable neurons in brain organoids Individuals with Angelman syndrome experience intellectual disability and seizures throughout their lives. In this condition, ubiquitin-mediated degradation of a key potassium channel is disrupted,…
Young's Modulus Determination of Normal and Glaucomatous Human Iris Open
View article: Probing physical origin of anisotropic thermal transport in black phosphorus nanoribbons
Probing physical origin of anisotropic thermal transport in black phosphorus nanoribbons Open
Black phosphorus (BP) has emerged as a promising candidate for next generation electronics and optoelectronics among the 2D family materials due to its extraordinary electrical/optical/optoelectronic properties. Interestingly, BP shows str…
View article: Effects of Processing Parameters on Surface Roughness of Additive Manufactured Ti-6Al-4V via Electron Beam Melting
Effects of Processing Parameters on Surface Roughness of Additive Manufactured Ti-6Al-4V via Electron Beam Melting Open
As one of the powder bed fusion additive manufacturing technologies, electron beam melting (EBM) is gaining more and more attention due to its near-net-shape production capacity with low residual stress and good mechanical properties. Thes…
View article: Graphene oxide inhibits malaria parasite invasion and delays parasitic growth
Graphene oxide inhibits malaria parasite invasion and delays parasitic growth Open
The interactions between graphene oxide (GO) and various biological entities have been actively investigated in recent years, resulting in numerous potential bioapplications of these nanomaterials. Despite this, the biological interactions…
View article: Ultralow thermal conductivity of single crystalline porous silicon nanowires
Ultralow thermal conductivity of single crystalline porous silicon nanowires Open
Porous materials provide a large surface to volume ratio, thereby providing a knob to alter fundamental properties in unprecedented ways. In thermal transport, porous nanomaterials can reduce thermal conductivity by not only enhancing phon…
View article: Orientational Coupling Locally Orchestrates a Cell Migration Pattern for Re‐Epithelialization
Orientational Coupling Locally Orchestrates a Cell Migration Pattern for Re‐Epithelialization Open
Re‐epithelialization by collective migration of epithelial cells over a heterogeneous environment to restore tissue integrity and functions is critical for development and regeneration. Here, it is reported that the spatial organization of…
View article: Graphene oxide inhibits malaria parasite invasion and delays parasitic growth<i>in vitro</i>
Graphene oxide inhibits malaria parasite invasion and delays parasitic growth<i>in vitro</i> Open
Graphene oxide nanosheets exhibit antimalarial property by inhibiting malaria parasite invasion and delaying parasitic growthin vitro.
View article: Microstructure and Wear Properties of Electron Beam Melted Ti-6Al-4V Parts: A Comparison Study against As-Cast Form
Microstructure and Wear Properties of Electron Beam Melted Ti-6Al-4V Parts: A Comparison Study against As-Cast Form Open
Ti-6Al-4V (Ti64) parts of varying thicknesses were additively manufactured (AM) by the powder-bed-based electron beam melting (EBM) technique. Microstructure and wear properties of these EBM-built Ti-6Al-4V parts have been investigated in …
View article: Reinforcing Low-Volume Fraction Nano-TiN Particulates to Monolithical, Pure Mg for Enhanced Tensile and Compressive Response
Reinforcing Low-Volume Fraction Nano-TiN Particulates to Monolithical, Pure Mg for Enhanced Tensile and Compressive Response Open
Novel Mg (0.58, 0.97, 1.98 and 2.5) vol. % TiN nanocomposites containing titanium nitride (TiN) nanoparticulates of ~20 nm size are successfully synthesized by a disintegrated melt deposition technique followed by hot extrusion. Microstruc…
View article: Effects of Primary Processing Techniques and Significance of Hall-Petch Strengthening on the Mechanical Response of Magnesium Matrix Composites Containing TiO2 Nanoparticulates
Effects of Primary Processing Techniques and Significance of Hall-Petch Strengthening on the Mechanical Response of Magnesium Matrix Composites Containing TiO2 Nanoparticulates Open
In the present study, Mg (1.98 and 2.5) vol % TiO2 nanocomposites are primarily synthesized utilizing solid-phase blend-press-sinter powder metallurgy (PM) technique and liquid-phase disintegrated melt deposition technique (DMD) followed b…
View article: Rapid, High-Throughput Tracking of Bacterial Motility in 3D via Phase-Contrast Holographic Video Microscopy
Rapid, High-Throughput Tracking of Bacterial Motility in 3D via Phase-Contrast Holographic Video Microscopy Open
Tracking fast-swimming bacteria in three dimensions can be extremely challenging with current optical techniques and a microscopic approach that can rapidly acquire volumetric information is required. Here, we introduce phase-contrast holo…
View article: Viscoelastic Effects of Silicone Gels at the Micro- and Nanoscale
Viscoelastic Effects of Silicone Gels at the Micro- and Nanoscale Open
There has been an increased use of silicone gel for applications such as cell traction force measurements as well as lab- and organ-on-chip systems. However, silicone gel is a viscoelastic material which tends to undergo non-elastic deform…