Mukhtiar Ahmad
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View article: <b>Comparison of Total Intravenous Anesthesia (TIVA) vs Inhalational Anesthesia on Recovery Profile in Day Care Surgeries</b>
<b>Comparison of Total Intravenous Anesthesia (TIVA) vs Inhalational Anesthesia on Recovery Profile in Day Care Surgeries</b> Open
Background: Ambulatory or day care surgeries have revolutionized perioperative care by enabling patients to undergo surgical procedures and return home the same day, improving efficiency, reducing costs, and enhancing patient satisfaction.…
View article: Impact of Acute Myeloid Leukemia Cells on the Metabolic Function of Bone Marrow Mesenchymal Stem Cells
Impact of Acute Myeloid Leukemia Cells on the Metabolic Function of Bone Marrow Mesenchymal Stem Cells Open
Acute myeloid leukemia (AML) proliferation is significantly influenced by the interactions between leukemia blasts and the bone marrow (BM) microenvironment. Specifically, bone marrow mesenchymal stem cells (BMSCs) derived from AML patient…
View article: <b>A Cross-Sectional Study on NPO Status and Its Fluctuation Rate in Pediatric Patients Undergoing Elective Surgeries: A Survey Based on Interviews</b>
<b>A Cross-Sectional Study on NPO Status and Its Fluctuation Rate in Pediatric Patients Undergoing Elective Surgeries: A Survey Based on Interviews</b> Open
Background: Prolonged preoperative fasting in pediatric patients can cause hypoglycemia, dehydration, and increased perioperative stress, yet adherence to evidence-based nil per os (NPO) guidelines remains inconsistent. International recom…
View article: The Impact of Spinal Anesthesia in Sitting Versus Lateral Decubitus Positions on Sensory Block Onset and Hemodynamic Stability in Lower Limb Surgeries
The Impact of Spinal Anesthesia in Sitting Versus Lateral Decubitus Positions on Sensory Block Onset and Hemodynamic Stability in Lower Limb Surgeries Open
Background: Spinal anesthesia is widely used in lower limb surgeries for its efficacy and safety, particularly in elderly patients. However, the optimal positioning during administration—sitting versus lateral decubitus—remains debated due…
View article: Pharmacological Comparison of Ketamine and Tramadol for Prevention of Shivering During Spinal Anesthesia
Pharmacological Comparison of Ketamine and Tramadol for Prevention of Shivering During Spinal Anesthesia Open
Background: Shivering is a frequent and uncomfortable complication following spinal anesthesia, contributing to increased metabolic demand, hemodynamic stress, and patient dissatisfaction. While both ketamine and tramadol are pharmacologic…
View article: Curcumin (Turmeric): A Carcinogenic, Miscarriage and Cirrhosis Causing Agent
Curcumin (Turmeric): A Carcinogenic, Miscarriage and Cirrhosis Causing Agent Open
Background: Curcumin, a compound derived from the turmeric plant (Curcuma longa), has been historically used in Asian cuisine and traditional medicine. It is known for its anti-inflammatory and antioxidant properties and is believed to hav…
View article: QUALITATIVE AND QUANTITATIVE PHYTOCHEMICAL SCREENING, OPTIMIZING THE EXTRACTION AND FRACTIONATION OF TANACETUM UMBELLIFERUM BY USING RESPONSE SURFACE METHODOLOGY
QUALITATIVE AND QUANTITATIVE PHYTOCHEMICAL SCREENING, OPTIMIZING THE EXTRACTION AND FRACTIONATION OF TANACETUM UMBELLIFERUM BY USING RESPONSE SURFACE METHODOLOGY Open
Phytochemicals are characterized as bioactive nutritional plant compounds that advantages extend beyond basic nutrition. The presence of various phytochemicals such as saponins, tannins, steroids, coumarins, terpenoids, anthocyanins, fatty…
View article: Anti-diabetic Potential of Indigenous Medicinal Plants of Cholistan Desert, Pakistan: A Review
Anti-diabetic Potential of Indigenous Medicinal Plants of Cholistan Desert, Pakistan: A Review Open
Cholistan Desert is a sandy desert located in southern Punjab, Pakistan. The area is rich in more than 64 medicinal plants among 138 plant species. It is noteworthy that this remote desert lacks modern health care facilities and its inhabi…
View article: ERRATUM: Mutations in the Bone Morphogenetic Protein 15 Gene Causing Defective Protein Secretion in Cholistani Infertile sheep
ERRATUM: Mutations in the Bone Morphogenetic Protein 15 Gene Causing Defective Protein Secretion in Cholistani Infertile sheep Open
[This corrects the article doi: 10.1590/1519-6984.256923].
View article: Phytohormones as Plant Growth Regulators and Safe Protectors against Biotic and Abiotic Stress
Phytohormones as Plant Growth Regulators and Safe Protectors against Biotic and Abiotic Stress Open
Plants are playing important role in the planet by providing food for humans and stability in the environment. Phytohormones are key regulators in various physiological processes and among the most important small signaling molecules affec…
View article: Carica papaya THERAPEUTIC PROPERTIES IN DISEASE MANAGEMENT: A REVIEW
Carica papaya THERAPEUTIC PROPERTIES IN DISEASE MANAGEMENT: A REVIEW Open
Carica papaya of (family: Caricaceae) is one of the mostly used plants. The papaya is well recognized for having nutritious and therapeutic importance. Various plant parts of papaya for example leaves, seeds, fruit, skin and roots have bee…
View article: Mutations in the bone morphogenetic protein 15 gene causing defective protein secretion in Cholistani infertile sheep
Mutations in the bone morphogenetic protein 15 gene causing defective protein secretion in Cholistani infertile sheep Open
Naturally occurring mutations in morphogenetic protein 15 (BMP15) are associated with decreased ovulation rate (OR), litter size (LS), and sterility. It is of a great interest to elucidate BMP15 gene in Cholistani sheep breed to uplift soc…
View article: Expression Characteristics and Significant Diagnostic and Prognostic Values of ANLN in Human Cancers
Expression Characteristics and Significant Diagnostic and Prognostic Values of ANLN in Human Cancers Open
Mukhtiar Ahmad,1,* Mehran Khan,2,* Rizwan Asif,3,* Nuzhat Sial,4,* Usman Abid,5,* Tahira Shamim,6 Zahid Hameed,7 Muhammad Junaid Iqbal,8,* Uroosa Sarfraz,8 Hina Saeed,1,* Zara Asghar,2 Madeeha Akram,2 Qamar Ullah,9 Qurat ul Ain Younas,10 L…
View article: A pan-cancer analysis of GINS complex subunit 4 to identify its potential role as a biomarker in multiple human cancers.
A pan-cancer analysis of GINS complex subunit 4 to identify its potential role as a biomarker in multiple human cancers. Open
This study was initiated to explore the expression variation, clinical significance, and biological importance of the GINS complex subunit 4 (GINS4) in different human cancers as a shared biomarker via pan-cancer analysis through different…
View article: Angiotensinogen - A Potential Diagnostic and Prognostic Candidate Gene &nbsp;for Adenocarcinomas of Rectum and Stomach
Angiotensinogen - A Potential Diagnostic and Prognostic Candidate Gene for Adenocarcinomas of Rectum and Stomach Open
The Angiotensinogen (AGT) gene encodes for angiotensinogen protein that mainly regulates blood pressure and maintains the fluid and salt balance in the body. AGT expression variations have been documented earlier in only a few subtypes of …
View article: Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancers
Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancers Open
Background: Defects in methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) expression have earlier been examined in only a few human cancers. Objectives: Multi-omics profiling of MTHFD1L as a shared biomarker in distinct subtypes of h…
View article: Up-regulation of GINS1 highlighted a good diagnostic and prognostic potential of survival in three different subtypes of human cancer
Up-regulation of GINS1 highlighted a good diagnostic and prognostic potential of survival in three different subtypes of human cancer Open
Cancer is a fatal malignancy and its increasing worldwide prevalence demands the discovery of more sensitive and reliable molecular biomarkers. To investigate the GINS1 expression level and its prognostic value in distinct human cancers us…
View article: CTHRC1 expression is a novel shared diagnostic and prognostic biomarker of survival in six different human cancer subtypes
CTHRC1 expression is a novel shared diagnostic and prognostic biomarker of survival in six different human cancer subtypes Open
View article: Multi-Omics Analysis Identified TMED2 as a Shared Potential Biomarker in Six Subtypes of Human Cancer
Multi-Omics Analysis Identified TMED2 as a Shared Potential Biomarker in Six Subtypes of Human Cancer Open
In conclusion, via this in silico study, we have elucidated that TMED2 can serve as a shared diagnostic and prognostic biomarker in CESC, ESCA, HNSC, KIRC, LIHC, and LUAD patients of different clinicopathological features but, further in v…
View article: Identification of correlation between human papillomavirus and prostate cancer: Bradford Hill Criteria Based Evaluation.
Identification of correlation between human papillomavirus and prostate cancer: Bradford Hill Criteria Based Evaluation. Open
Background: Human papillomavirus (HPV) association has effectively been decoded in prostate cancer (PC) worldwide with controverting conclusions. Though the different groups of researchers explored the potential association of HPV with PC …
View article: Does mouse mammary tumor-like virus cause human breast cancer? Applying Bradford Hill criteria postulates
Does mouse mammary tumor-like virus cause human breast cancer? Applying Bradford Hill criteria postulates Open
Background The role of mouse mammary tumor-like virus (MMTV-like virus) in human breast cancer (BC) has already been widely investigated worldwide with conflicting results. Although the researchers tried to establish the link between MMTV-…
View article: Does human papillomavirus cause human colorectal cancer? Applying Bradford Hill criteria postulates
Does human papillomavirus cause human colorectal cancer? Applying Bradford Hill criteria postulates Open
The role of human papillomavirus (HPV) in human colorectal cancer (CRC) has already been widely investigated worldwide with conflicting results. Although researchers have tried to establish the link between HPV and CRC through a statistica…
View article: Does epstein–barr virus participate in the development of breast cancer? A brief and critical review with molecular evidences
Does epstein–barr virus participate in the development of breast cancer? A brief and critical review with molecular evidences Open
The oncogenic potential of Epstein–Barr virus (EBV) has been well studied in human breast cancer (BC) so far but still controversies surround its role. In the present study, we aimed to perform a comprehensive and critical review of the re…
View article: Risk Factors and Epidemiology of Gastric Cancer in Pakistan
Risk Factors and Epidemiology of Gastric Cancer in Pakistan Open
Gastric cancer is the 2nd most common cause of death among all cancers and is the 4th most common cancer in the world. The number of deaths due to gastric cancer is about 800,000 annually. Gastric cancer is more common in men as compared t…