Munir Chowdhury
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View article: Surface-based morphometry reveals divergent aging trajectories in veterans with and without traumatic brain injury
Surface-based morphometry reveals divergent aging trajectories in veterans with and without traumatic brain injury Open
This study investigates how traumatic brain injury (TBI) alters cortical aging by comparing cortical thickness (CT) and surface area (SA) in 34 brain regions between TBI survivors and age-matched controls. Using a cross-sectional retrospec…
View article: Eeg-Based Neuromodulatory Effects of Transcutaneous Electrical Nerve Stimulation in Sports Injury Rehabilitation: A Focus on Alpha and Beta Bands
Eeg-Based Neuromodulatory Effects of Transcutaneous Electrical Nerve Stimulation in Sports Injury Rehabilitation: A Focus on Alpha and Beta Bands Open
View article: Psychometric Validation of the Bangla Version of the Breast Cancer Fear Scale Among Female University Students in Bangladesh
Psychometric Validation of the Bangla Version of the Breast Cancer Fear Scale Among Female University Students in Bangladesh Open
Background: Research suggests that fear of cancer could be a significant predictor influencing participation in cancer screening. However, no tools have been validated to measure breast cancer fear among women in Bangladesh, while the Brea…
View article: Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia prediction
Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia prediction Open
DNA methylation age (MA), brain age (BA), and frailty index (FI) are putative aging biomarkers linked to dementia risk. We investigated their relationship and combined potential for prediction of cognitive impairment and future dementia ri…
View article: Correction: Polygenic effects on the risk of Alzheimer’s disease in the Japanese population
Correction: Polygenic effects on the risk of Alzheimer’s disease in the Japanese population Open
View article: Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer’s disease
Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer’s disease Open
View article: Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort
Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort Open
View article: Issue Information
Issue Information Open
View article: A novel spatiotemporal graph convolutional network framework for functional connectivity biomarkers identification of Alzheimer’s disease
A novel spatiotemporal graph convolutional network framework for functional connectivity biomarkers identification of Alzheimer’s disease Open
Background Functional connectivity (FC) biomarkers play a crucial role in the early diagnosis and mechanistic study of Alzheimer’s disease (AD). However, the identification of effective FC biomarkers remains challenging. In this study, we …
View article: Polygenic effects on the risk of Alzheimer’s disease in the Japanese population
Polygenic effects on the risk of Alzheimer’s disease in the Japanese population Open
Background Polygenic effects have been proposed to account for some disease phenotypes; these effects are calculated as a polygenic risk score (PRS). This score is correlated with Alzheimer’s disease (AD)-related phenotypes, such as biomar…
View article: Issue Information
Issue Information Open
View article: Glucose metabolism in posterior cingulate cortex has supplementary value to predict the progression of cognitively unimpaired to dementia due to Alzheimer’s disease: an exploratory study of 18F-FDG-PET
Glucose metabolism in posterior cingulate cortex has supplementary value to predict the progression of cognitively unimpaired to dementia due to Alzheimer’s disease: an exploratory study of 18F-FDG-PET Open
View article: Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment
Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment Open
View article: Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease
Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease Open
Importance Knowledge is lacking on the prevalence and prognosis of individuals with a β-amyloid–negative, tau-positive (A−T+) cerebrospinal fluid (CSF) biomarker profile. Objective To estimate the prevalence of a CSF A−T+ biomarker profile…
View article: Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank
Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank Open
Background Identifying prediagnostic neurodegenerative disease is a critical issue in neurodegenerative disease research, and Alzheimer’s disease (AD) in particular, to identify populations suitable for preventive and early disease-modifyi…
View article: Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease
Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease Open
For optimal design of anti-amyloid-β (Aβ) and anti-tau clinical trials, we need to better understand the pathophysiological cascade of Aβ- and tau-related processes. Therefore, we set out to investigate how Aβ and soluble phosphorylated ta…
View article: A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease
A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease Open
View article: Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment
Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment Open
View article: Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume Open
The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associ…
View article: Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease
Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease Open
View article: In vivo staging of regional amyloid deposition
In vivo staging of regional amyloid deposition Open
To estimate a regional progression pattern of amyloid deposition from cross-sectional amyloid-sensitive PET data and evaluate its potential for in vivo staging of an individual's amyloid pathology.
View article: Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease
Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease Open
The original version of the Supplementary information associated with this Article inadvertently omitted Supplementary Table S1. The HTML has been updated to include a corrected version of the Supplementary information.
View article: KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease Open
View article: Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration Open
Background The Apolipoprotein E ε4 allele (i.e. ApoE4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). TREM2 (i.e. Triggering receptor expressed on myeloid cells 2) is a microglial transmembrane protein brain th…
View article: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease
Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease Open
View article: Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease
Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease Open
View article: Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau
Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau Open
In this study, we aimed to assess whether women are able to withstand more tau before exhibiting verbal memory impairment. Using data from 121 amyloid-β-positive Alzheimer’s Disease Neuroimaging Initiative participants, we fit a linear mod…
View article: Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways
Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways Open
View article: Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk Open
Alzheimer’s disease (AD) is a leading cause of mortality in the elderly. While the coding change of APOE -ε4 is a key risk factor for late-onset AD and has been believed to be the only risk factor in the APOE locus, it does not fully expla…
View article: The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory Open