Munir Ullah Khan
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View article: A Route to Sulfur‐Containing Polymers via FeFe‐DMCC‐Catalyzed Copolymerization of Propylene Oxide and Carbonyl Sulfide
A Route to Sulfur‐Containing Polymers via FeFe‐DMCC‐Catalyzed Copolymerization of Propylene Oxide and Carbonyl Sulfide Open
This study investigates the development of the iron‐based catalyst FeFe‐DMCC for the efficient copolymerization of carbonyl sulfide (COS) and propylene oxide (PO), leading to the production of poly(propylene monothiocarbonate)s (PPMTC). Th…
View article: First Principles Calculation Guided Material Selection of Poly(propylenemonothiocarbonate) for High-Performance Triboelectric Nanogenerators
First Principles Calculation Guided Material Selection of Poly(propylenemonothiocarbonate) for High-Performance Triboelectric Nanogenerators Open
The advancement of the information era has raised growing interest in triboelectric nanogenerators (TENGs) as environmentally friendly micropower sources. However, most developments to increase the power outputs of TENGs have focused on tr…
View article: Genetic Alchemy unveiled: MicroRNA-mediated gene therapy as the Artisan craft in the battlefront against hepatocellular carcinoma—a comprehensive chronicle of strategies and innovations
Genetic Alchemy unveiled: MicroRNA-mediated gene therapy as the Artisan craft in the battlefront against hepatocellular carcinoma—a comprehensive chronicle of strategies and innovations Open
Investigating therapeutic miRNAs is a rewarding endeavour for pharmaceutical companies. Since its discovery in 1993, our understanding of miRNA biology has advanced significantly. Numerous studies have emphasised the disruption of miRNA ex…
View article: Cardiovascular diseases crossroads: cGAS-STING signaling and disease progression
Cardiovascular diseases crossroads: cGAS-STING signaling and disease progression Open
View article: Natural Allies for Heart Health: Nrf2 Activation and Cardiovascular Disease Management
Natural Allies for Heart Health: Nrf2 Activation and Cardiovascular Disease Management Open
View article: TME-targeted approaches of brain metastases and its clinical therapeutic evidence
TME-targeted approaches of brain metastases and its clinical therapeutic evidence Open
The tumor microenvironment (TME), which includes both cellular and non-cellular elements, is now recognized as one of the major regulators of the development of primary tumors, the metastasis of which occurs to specific organs, and the res…
View article: Reprogramming tumor-associated macrophages as a unique approach to target tumor immunotherapy
Reprogramming tumor-associated macrophages as a unique approach to target tumor immunotherapy Open
In the last ten years, it has become increasingly clear that tumor-infiltrating myeloid cells drive not just carcinogenesis via cancer-related inflammatory processes, but also tumor development, invasion, and metastasis. Tumor-associated m…
View article: Role of LGMN in tumor development and its progression and connection with the tumor microenvironment
Role of LGMN in tumor development and its progression and connection with the tumor microenvironment Open
Legumain (LGMN) has been demonstrated to be overexpressed not just in breast, prostatic, and liver tumor cells, but also in the macrophages that compose the tumor microenvironment. This supports the idea that LGMN is a pivotal protein in r…
View article: Applications of Extracellular Vesicles in Nervous System Disorders: An Overview of Recent Advances
Applications of Extracellular Vesicles in Nervous System Disorders: An Overview of Recent Advances Open
Diseases affecting the brain and spinal cord fall under the umbrella term “central nervous system disease”. Most medications used to treat or prevent chronic diseases of the central nervous system cannot cross the blood–brain barrier (BBB)…
View article: Unique therapeutic potentialities of exosomes based nanodrug carriers to target tumor microenvironment in cancer therapy
Unique therapeutic potentialities of exosomes based nanodrug carriers to target tumor microenvironment in cancer therapy Open
Cancer is a complex syndrome with a high mortality rate worldwide due to the lack of effective treatments. The lack of effective coordination between tumor cells and immune system components may be an important reason for the failure of tu…
View article: Recent Developments in Quorum Sensing-Based Suppression of Intestinal Pathogenic Bacteria
Recent Developments in Quorum Sensing-Based Suppression of Intestinal Pathogenic Bacteria Open
Quorum sensing (QS) is a way for bacteria to communicate with each other. It works by making, releasing, and identifying AIs (autoinducers). It is critical for the growth of microorganisms and is a vital component of the immune system. In …
View article: Advances in innate immune memory of macrophages
Advances in innate immune memory of macrophages Open
Immunity is usually classified into two categories: innate immunity and adaptive immunity, distinguished by the process and characteristics of the immunological impact. It was widely assumed that only adaptive immunity possessed memory fea…
View article: Treatment of diabetic muscular hyperplasia with natural and nutritional supplements
Treatment of diabetic muscular hyperplasia with natural and nutritional supplements Open
Skeletal muscle is an important part of the human body. Most glucose metabolism is accomplished by skeletal muscle through insulin mediation. Skeletal muscle metabolism disorder can affect glucose metabolic homeostasis and insulin sensitiv…
View article: Extra Chromosomal Circular DNA: Recent Advances in Research
Extra Chromosomal Circular DNA: Recent Advances in Research Open
Extrachromosomal circular DNA (eccDNA) is a circular DNA molecule outside of eukaryotic staining, in which DNA forms in the genome or exogenous DNA in the cell. eccDNA is a special class of genetic material that can carry complete genes en…
View article: The Role of Amino Acid Metabolic Reprogramming in Tumor Development and Immunotherapy
The Role of Amino Acid Metabolic Reprogramming in Tumor Development and Immunotherapy Open
Many amino acid transporters are solvent carrier proteins, which are membrane transport proteins. In order for cells of all kinds to thrive, including cancerous ones, they need a constant supply of amino acids, which are important for grow…
View article: The mechanism of mammalian mitochondrial quality control system
The mechanism of mammalian mitochondrial quality control system Open
The mitochondria perform an essential role in cellular metabolism by acting as a cellular energy powerhouse. It is also involved in several biological processes such as cell metabolism, stress signaling, calcium homeostasis, and reactive o…
View article: Therapeutic Application of Genetically Engineered Ribosome-Inactivating Toxin Proteins for Cancer
Therapeutic Application of Genetically Engineered Ribosome-Inactivating Toxin Proteins for Cancer Open
Recently, Ribosome-Inactivating Proteins (RIPs) as a class of anticancer medicines have garnered considerable attention due to their novel anticancer mechanism. Although the medications are small, RIPs utilize the Large-Size Effect (LSE) t…
View article: Recent Developments and Applications of Single-Cell RNA Sequencing Technology in Cell Classification
Recent Developments and Applications of Single-Cell RNA Sequencing Technology in Cell Classification Open
Multicellular organisms have many cell types and are complex, and heterogeneity is common among cells. Single-Cell RNA Sequencing (scRNA-SEQ) is a new technique for studying the transcriptional activity of a single cell that is still in it…
View article: Review on Gene regulation: DNA-protein and protein-protein interactions and their regulatory elements
Review on Gene regulation: DNA-protein and protein-protein interactions and their regulatory elements Open
The non-coding elements that control transcription are found in the chromatin structure of organisms. Recent findings identify the non-coding regulatory elements (e.g., enhancers, silencers, promoters) that control transcription and examin…
View article: A Scientific Breakthrough in the Regulatory Mechanism of Histone Degradation
A Scientific Breakthrough in the Regulatory Mechanism of Histone Degradation Open
View article: Innentitelbild: Pt<sub>3</sub>Co Octapods as Superior Catalysts of CO<sub>2</sub> Hydrogenation (Angew. Chem. 33/2016)
Innentitelbild: Pt<sub>3</sub>Co Octapods as Superior Catalysts of CO<sub>2</sub> Hydrogenation (Angew. Chem. 33/2016) Open
Mehrere Pt/Co-Nanopartikel wurden von J. Zeng, Z. Wang et al. als Katalysatoren der CO2-Hydrierung getestet. Wie sie in der Zuschrift auf S. 9700 ff. schildern, verleihen die vielen scharfen Spitzen und der Ladungstransfer zwischen Pt und …