Murante Thomas
YOU?
Author Swipe
View article: The biofilm TF network contains feedforward loops that regulate <i>BCR1</i> expression.
The biofilm TF network contains feedforward loops that regulate <i>BCR1</i> expression. Open
(A) A summary of the phenotypic genetic interaction network for the biofilm TFs. (B) Three network modules that show both phenotypic interactions and downstream target expression changes consistent feedforward loops. The numbers in parenth…
View article: The <i>ndt80</i>Δ/<i>NDT80</i> and <i>bcr1</i>Δ/<i>BCR1</i> show altered biofilm architecture.
The <i>ndt80</i>Δ/<i>NDT80</i> and <i>bcr1</i>Δ/<i>BCR1</i> show altered biofilm architecture. Open
Confocal microscopy images of wild type, ndt80Δ/NDT80, bcr1Δ/BCR1, tec1Δ/TEC1, and ndt80Δ/NDT80 tec1Δ/TEC1 strains grown in YETS for 48 hr. Cells were stained with concanavalin A. See Materials and methods for full details. The top image i…
View article: Heterozygous deletion mutants of six core biofilm transcription factors show simple and complex hapoinsufficiency for biofilm density.
Heterozygous deletion mutants of six core biofilm transcription factors show simple and complex hapoinsufficiency for biofilm density. Open
(A) The density of the biofilms formed by the indicated wild type (SN250), heterozygous and homozygous deletion strains was determined by measuring the OD600 after incubation for 48 hr as described in Materials and Methods (YETS medium). T…
View article: Epistasis analysis of the biofilm density for the biofilm TF network.
Epistasis analysis of the biofilm density for the biofilm TF network. Open
(A) The nomarlized biofilm density (NBD) for each double heterozygote mutant was determined after 48 hr biofilm formation as described in Materials and Methods. The predicted NBD for each double heterozygous mutant was calculated by multip…
View article: The altered architecture of <i>ndt80</i>Δ/<i>NDT80</i> is strongly dependent on Rob1 and Tec1.
The altered architecture of <i>ndt80</i>Δ/<i>NDT80</i> is strongly dependent on Rob1 and Tec1. Open
(A) Complementation of ndt80Δ/NDT80 with an allele under endogenous promoter restores wild type levels of normalized biofilm density (NBD) NBD=OD600 mutant/OD600 wild type. The blue bar indicates statistically significant increase relative…