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View article: The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications
The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications Open
Lung cancer remains the leading cause of cancer‐related death in both women and men in the United States and globally. Even among early‐stage patients who undergo surgical resection, a significant portion of patients develop metastases. No…
View article: Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors
Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors Open
Recurrent fusion transcripts, which are one of the characteristic hallmarks of cancer, arise either from chromosomal rearrangements or from transcriptional errors in splicing. DNA rearrangements include intrachromosomal or interchromosomal…
View article: Next generation sequencing and its applications in HPVassociated cancers
Next generation sequencing and its applications in HPVassociated cancers Open
Approximately 18% of all human cancers have a viral etiology, and human papillomavirus (HPV) has been identified as one of the most prevalent viruses that plays causative role in nearly all cervical cancers and, in addition, in subset of h…