Explanipedia

Predictors of in-hospital mortality in elderly patients with heart failure treated with tolvaptan. Open

Masakazu Kobayashi, Mutsuharu Hayashi, Ryo Yamada, Tomoya Ishiguro, Wakaya Fujiwara , et al. · 2023

This study revealed that a higher heart rate and higher BUN levels were independent factors for in-hospital prognosis in elderly patients who received tolvaptan and that early tolvaptan use may not always be effective in elderly patients.

Supplementary Material for: Long-Term Proton Pump Inhibitor Therapy Increases the Risk of Infection in Patients with Incident Hemodialysis Open

Yosuke Saka, T. Naruse, T. Chikamatsu, K. Mitani, Mutsuharu Hayashi , et al. · 2023

Background: Infection is one of the most common causes of death in patients with chronic kidney disease (CKD). Proton pump inhibitors (PPIs) are not only widely used in patients with CKD but also represent a known risk factor…

Combined Assessment of D-Dimer with the Get with the Guidelines—Heart Failure Risk Score and N-Terminal Pro-B-Type Natriuretic Peptide in Patients with Acute Decompensated Heart Failure with Preserved and Reduced Ejection Fraction Open

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Eirin Sakaguchi , et al. · 2021

The prognostic role of D-dimer in different types of heart failure (HF) is poorly understood. We investigated the prognostic value of D-dimer on admission, both independently and in combination with the Get With The Guidelines—Heart Failur…

Circulating miR-489 as a potential new biomarker for idiopathic dilated cardiomyopathy. Open

Tomoya Ishiguro, Mutsuharu Hayashi, Wakaya Fujiwara, Satoshi Okumura, Masataka Yoshinaga , et al. · 2021

Our results suggest that circulating miR-489 could be a potential noninvasive diagnostic biomarker for DCM. Additionally, the quantification of circulating miR-489 may have value as a potential prognostic marker for patients with DCM.

Effect of cardiac rehabilitation on circulating microRNA expression in heart failure: a preliminary study. Open

Ryo Yamada, Satoshi Okumura, Yuji Kono, A. Miyazaki, Yudai Niwa , et al. · 2021

When performing CR, expression of certain circulating miRNAs in patients with HF is restored to nonpathological levels. The benefits of CR for HF may result from regulation of miRNAs through multiple effects of gene expression.

Impact of physical function on indeterminable anaerobic threshold in patients with heart failure. Open

Sayano Ueda, Yuji Kono, Ryo Yamada, Tomoya Ishiguro, Masataka Yoshinaga , et al. · 2021

The present study identified handgrip strength and walking speed as powerful predictors for indeterminable AT with HF.

Urinary Liver-Type Fatty-Acid-Binding Protein Predicts Long-Term Adverse Outcomes in Medical Cardiac Intensive Care Units Open

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Hideto Nishimura , et al. · 2020

We prospectively investigated the prognostic value of urinary liver-type fatty-acid-binding protein (L-FABP) levels on hospital admission, both independently and in combination with serum creatinine-defined acute kidney injury (AKI), to pr…

Predictive impact of early mobilization on rehospitalization for elderly Japanese heart failure patients Open

Yuji Kono, Hideo Izawa, Yoichiro Aoyagi, Ayako Ishikawa, Tsubasa Sugiura , et al. · 2019

Predicting acute kidney injury using urinary liver-type fatty-acid binding protein and serum N-terminal pro-B-type natriuretic peptide levels in patients treated at medical cardiac intensive care units Open

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Hideto Nishimura , et al. · 2018

Predictors of clinical outcome in heart failure patients treated with vasopressin type 2 receptor antagonist Open

Takehiro Ito, Daiji Yoshikawa, Mutsuharu Hayashi, Masataka Yoshinaga, Tomoya Ishiguro , et al. · 2018

Objectives: There are well-established risk prediction models of in-hospital mortality due to heart failure (HF). However, the predictors of mortality during acute hospitalization in individuals with HF receiving tolvaptan, a vasopressin t…

Serum microRNA-126 and -223 as new-generation biomarkers for sarcoidosis in patients with heart failure Open

Wakaya Fujiwara, Yasuchika Kato, Mutsuharu Hayashi, Yoshinori Sugishita, Satoshi Okumura , et al. · 2018

Prognostic Value of Combination of Plasma D-Dimer Concentration and Estimated Glomerular Filtration Rate in Predicting Long-Term Mortality of Patients With Stable Coronary Artery Disease Open

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Ryuunosuke Okuyama , et al. · 2017

The combinatorial value of assessing D-dimer levels and eGFR may provide useful insight regarding stable CAD patients' long-term risk stratification.

Hospitalization Deteriorates Performance of Activities of Daily Living by Super-Elderly Patients With Heart Failure Open

Hideo Izawa, Yuji Kohno, Wakaya Fujiwara, Mutsuharu Hayashi · 2016

Persistent Excessive Electrocardiogram ST-segment Elevation in a Patient with a Takotsubo Syndrome: What Could be the Cause? Open

Mutsuharu Hayashi, Tomohito Kamada, Hiroatsu Yokoi, Wakaya Fujiwara, Daiji Yoshikawa , et al. · 2016

Identification of an Interaction between VWF rs7965413 and Platelet Count as a Novel Risk Marker for Metabolic Syndrome: An Extensive Search of Candidate Polymorphisms in a Case-Control Study Open

Masahiro Nakatochi, Yasunori Ushida, Yoshinari Yasuda, Yukiko Yoshida, Shun Kawai , et al. · 2015

Although many single nucleotide polymorphisms (SNPs) have been identified to be associated with metabolic syndrome (MetS), there was only a slight improvement in the ability to predict future MetS by the simply addition of SNPs to clinical…

Left ventricular dyssynchrony in patients with moderate coronary stenosis and border line fractional flow reserve. Open

Yohei Shibata, Takahito Sone, Hideyuki Tsuboi, Satoshi Isobe, Hideki Ishii , et al. · 2015

The cutoff values of fractional flow reserve (FFR) to detect physiological myocardial ischemia are still controversial. Some studies have reported that left ventricular (LV) dyssynchrony occurs in patients with coronary artery disease (CAD…

Clinical Characteristics and Long-Term Outcomes of Hypertrophic Cardiomyopathy Open

Masataka Yoshinaga, Daiji Yoshikawa, Hideki Ishii, Akihiro Hirashiki, Takahiro Okumura , et al. · 2015

Hypertrophic cardiomyopathy (HCM) has various morphological and clinical features. A decade has passed since the previous survey of the epidemiological and clinical characteristics of Japanese HCM patients. The Aichi Hypertrophic Cardiomyo…

Takotsubo Cardiomyopathy with Involvement of Delayed-onset Rhabdomyolysis and Acute Kidney Injury after Rosuvastatin Treatment Open

Tomohito Kamada, Mutsuharu Hayashi, Hiroatsu Yokoi, Wakaya Fujiwara, Daiji Yoshikawa , et al. · 2015

Takotsubo cardiomyopathy is a disorder characterized by left ventricular apical ballooning with preceding emotional and/or physical stressors. This condition is also an important differential diagnosis of acute coronary syndrome. We herein…

The effect of cardiac rehabilitation on long-term outcome in patients with chronic heart failure Open

Yuji Kono, Tomoko Kayukawa, Yoichiro Aoyagi, Eiichi Saito, Wakaya Fujiwara , et al. · 2015

The effect of cardiac rehabilitation on long-term outcome in patients with chronic

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