Mutsumi Inamatsu
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View article: Gut–liver microphysiological systems revealed potential crosstalk mechanism modulating drug metabolism
Gut–liver microphysiological systems revealed potential crosstalk mechanism modulating drug metabolism Open
The small intestine and liver play important role in determining oral drug's fate. Both organs are also interconnected through enterohepatic circulation, which imply there are crosstalk through circulating factors such as signaling molecul…
View article: Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply Open
Functional bile canaliculus formation in cultured human hepatocytes is crucial for in vitro studies of hepatobiliary disposition and drug-induced cholestasis. Human hepatocytes isolated from humanized mouse livers (PXB-cells) are promising…
View article: The Evaluation of Lipid Analysis for PXB-Cells LA as a Human Non-Alcoholic Fatty Liver Disease Model
The Evaluation of Lipid Analysis for PXB-Cells LA as a Human Non-Alcoholic Fatty Liver Disease Model Open
View article: Development of the Heart Endocardium at an Early Stage of Chick Embryos Evaluated at Light‐ and Electron‐Microscopic Levels
Development of the Heart Endocardium at an Early Stage of Chick Embryos Evaluated at Light‐ and Electron‐Microscopic Levels Open
Development of the endocardium in the heart of 4 to 4·1/2‐day‐incubated chick embryos was observed light and electron microscopically, and these results were evaluated by immunohistochemistry for desmin, FLK1 (VEGFR‐2) or CD31, and by in s…
View article: Restorative effect of hair follicular dermal cells on injured human hair follicles in a mouse model
Restorative effect of hair follicular dermal cells on injured human hair follicles in a mouse model Open
No model is available for examining whether in vivo ‐damaged human hair follicles (hu‐ HF s) are rescued by transplanting cultured hu‐ HF dermal cells (dermal papilla and dermal sheath cells). Such a model might be valuable for examining w…