Mengwei Xu
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View article: Third-generation versus first-generation EGFR tyrosine kinase inhibitors in Asian patients with advanced EGFR mutant non-small cell lung cancer: a meta-analysis of randomized controlled trials
Third-generation versus first-generation EGFR tyrosine kinase inhibitors in Asian patients with advanced EGFR mutant non-small cell lung cancer: a meta-analysis of randomized controlled trials Open
Compared with FGETs, TGETs significantly improve PFS, CNS control, response outcomes, and maintain a comparable safety profile for Asian patients with advanced EGFR-mutated NSCLC.
View article: Elucidating the binding mechanism of silver carp myosin to T-2 toxin using multi-spectroscopic analysis, molecular docking and molecular dynamics simulation
Elucidating the binding mechanism of silver carp myosin to T-2 toxin using multi-spectroscopic analysis, molecular docking and molecular dynamics simulation Open
View article: Small Language Models: Survey, Measurements, and Insights
Small Language Models: Survey, Measurements, and Insights Open
Small language models (SLMs), despite their widespread adoption in modern smart devices, have received significantly less academic attention compared to their large language model (LLM) counterparts, which are predominantly deployed in dat…
View article: Successful treatment with bortezomib in combination with dexamethasone in a middle-aged male with idiopathic multicentric Castleman’s disease: A case report
Successful treatment with bortezomib in combination with dexamethasone in a middle-aged male with idiopathic multicentric Castleman’s disease: A case report Open
Multicentric Castleman disease (MCD) is a heterogeneous, life-threatening disease. A subgroup of HIV-negative and HHV-8-negative MCD is defined as idiopathic MCD (iMCD) with a poor prognosis. Here we report an unusual case of a 47-year-old…
View article: Elucidating the Binding Mechanism Of Silver Carp Myosin To T-2 Toxin Using Multi-Spectroscopic Analysis, Molecular Docking and Molecular Dynamics Simulation
Elucidating the Binding Mechanism Of Silver Carp Myosin To T-2 Toxin Using Multi-Spectroscopic Analysis, Molecular Docking and Molecular Dynamics Simulation Open
View article: Construction and experimental validation of ferroptosis-related competing endogenous RNA networks in hepatocellular carcinoma based on WGCNA
Construction and experimental validation of ferroptosis-related competing endogenous RNA networks in hepatocellular carcinoma based on WGCNA Open
The ferroptosis-related competing endogenous RNAs (ceRNA) network in hepatocellular carcinoma (HCC) has not been fully explored. In this study, RNA sequence data of HCC and clinic data were downloaded from The Cancer Genome Atlas (TCGA) da…
View article: Borderline ovarian tumor in the pediatric and adolescent population: a clinopathologic analysis of fourteen cases.
Borderline ovarian tumor in the pediatric and adolescent population: a clinopathologic analysis of fourteen cases. Open
Borderline ovarian tumors (BOTs) are rare among children and adolescents. This study was to probe into the clinicopathologic characteristics and prognosis in children and adolescents with BOT. A retrospective investigation was performed on…
View article: CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma
CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma Open
The molecular and clinical heterogeneity in diffuse large B‑cell lymphoma (DLBCL) has raised a need for the investigation of potential therapeutic biomarkers. MicroRNA‑320 (miR‑320) and CDK6 are both involved in the regulation of cell prol…
View article: Expression and clinical significance of miR‑23a and MTSS1 in diffuse large B‑cell lymphoma
Expression and clinical significance of miR‑23a and MTSS1 in diffuse large B‑cell lymphoma Open
The present study investigated the expression and clinical significance of micro-ribonucleic acid-23a (miR-23a) and metastasis suppressor 1 (MTSS1) in diffuse large B-cell lymphoma (DLBCL). A total of 70 cases of tumor tissues of patients …
View article: Short Call Abstracts
Short Call Abstracts Open
Hu ¨rthle cell (oncocytic) carcinoma is an uncommon form of thyroid cancer exhibiting follicular patterned growth, radioactive iodine resistance, and an accumulation of mitochondria.Focused DNA sequencing of small numbers of tumors has rev…