Muya Chen
2023
Multi-omics analysis reveals signatures of selection and loci associated with complex traits in pigs
2023 • Guoqiang Yi, Lei Liu, Yilong Yao, Yuwen Liu, Li Jiang, Yalan Yang, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Liyuan Wang...
2022
Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs
2022 • Yuwen Liu, Yang Fu, Yalan Yang, Guoqiang Yi, Jinmin Lian, Bingkun Xie, Yilong Yao, Muya Chen, Yongchao Niu, Lei Liu, Liyuan Wang, Yongsheng Zhang,...
2022
Additional file 2 of Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs
2022 • Yuwen Liu, Yang Fu, Yalan Yang, Guoqiang Yi, Jinmin Lian, Bingkun Xie, Yilong Yao, Muya Chen, Yongchao Niu, Lei Liu, Liyuan Wang, Yongsheng Zhang,...
2021
Landscape of tissue-specific RNA Editome provides insight into co-regulated and altered gene expression in pigs (<i>Sus-scrofa</i>)
2021 • Adeyinka Abiola Adetula, Xinhao Fan, Yongsheng Zhang, Yilong Yao, Junyu Yan, Muya Chen, Yijie Tang, Yuwen Liu, Guoqiang Yi, Kui Li, Zhonglin Tang
2024
Multiomics analysis reveals signatures of selection and loci associated with complex traits in pigs
2024 • Lei Liu, Guoqiang Yi, Yilong Yao, Yuwen Liu, Jiang Li, Yalan Yang, Mei Liu, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Li...
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Exploring foci of
2024-12-01
Multiomics analysis reveals signatures of selection and loci associated with complex traits in pigs
2024-12-01 • Lei Liu, Guoqiang Yi, Yilong Yao, Yuwen Liu, Jiang Li, Yalan Yang, Mei Liu, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Li...
Abstract The genetic basis of complex traits and phenotypic differentiation remains unclear in pigs. Using nine genomes—seven of which were newly generated, high‐quality de novo assembled genomes—and 1081 resequencing genomes, we built a pan‐genome and identified 134.24 Mb nonredundant nonreference sequences, 1099 novel protein‐coding genes, 187,927 structural variations (SVs) and 30,143,962 single‐nucleotide polymorphisms (SNPs). Analysis of selective domestication revealed BRCA1 associated with enhanced adipocyt…
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Slope Stability Analysis
Thermogravimetric Analysis
Functional Analysis
Multiple-Criteria Decision Analysis
Self-Monitoring, Analysis And Reporting Technology
Sieve Analysis
Spatial Analysis
Musical Analysis
Image Analysis
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Exploring foci of
2023-09-21
Multi-omics analysis reveals signatures of selection and loci associated with complex traits in pigs
2023-09-21 • Guoqiang Yi, Lei Liu, Yilong Yao, Yuwen Liu, Li Jiang, Yalan Yang, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Liyuan Wang...
Abstract Selection signatures that contribute to phenotypic diversity, especially morphogenesis in pigs, remain to be further elucidated. To reveal the regulatory role of genetic variations in phenotypic differences between Eastern and Western pig breeds, we performed a systematic analysis based on seven high-quality de novo assembled genomes, 1,081 resequencing data representing 78 domestic breeds, 162 methylomes, and 162 transcriptomes of skeletal muscle from Tongcheng (Eastern) and Landrace (Western) pigs at 27…
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Slope Stability Analysis
Exploratory Factor Analysis
Thermogravimetric Analysis
Analysis Of Western European Colonialism And Colonization
Nodal Analysis
Functional Analysis
Requirements Analysis
Technical Analysis
Self-Monitoring, Analysis And Reporting Technology
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Exploring foci of
2022-09-14
Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs
2022-09-14 • Yuwen Liu, Yang Fu, Yalan Yang, Guoqiang Yi, Jinmin Lian, Bingkun Xie, Yilong Yao, Muya Chen, Yongchao Niu, Lei Liu, Liyuan Wang, Yongsheng Zhang,...
Abstract Background The genetic mechanisms that underlie phenotypic differentiation in breeding animals have important implications in evolutionary biology and agriculture. However, the contribution of cis-regulatory variants to pig phenotypes is poorly understood. Therefore, our aim was to elucidate the molecular mechanisms by which non-coding variants cause phenotypic differences in pigs by combining evolutionary biology analyses and functional genomics. Results We obtained a high-resolution phased chromosome-sc…
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Computer Data Storage
Tokenization (Data Security)
Data Fusion
Erwin Data Modeler
Digimon Data Squad
Data Scrubbing
Enterprise Application Integration
Data Validation
System Integration Testing
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Exploring foci of
2022-01-01
Additional file 2 of Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs
2022-01-01 • Yuwen Liu, Yang Fu, Yalan Yang, Guoqiang Yi, Jinmin Lian, Bingkun Xie, Yilong Yao, Muya Chen, Yongchao Niu, Lei Liu, Liyuan Wang, Yongsheng Zhang,...
Additional file 2: Table S1. Statistics of the resequencing data produced by this study. Table S2. Overview of the data that were downloaded from NCBI. Table S3. Statistics of the NCBI data—according to run_ID. Table S4. Primers used in this study. Table S5. Information on the luciferase reporter assay for 10 selected potential enhancers. Table S6. siRNA sequences used in this study. Table S7. BioNano optical maps of the Luchuan pig. Table S8. Statistics of the two haplotigs in each step of assembly processes. Tab…
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File (Command)
Computer File
Continuous Integration
Andrew File System
Comparison Of Distributed File Systems
Comparison Of File Synchronization Software
Timeline Of File Sharing
Enterprise Application Integration
Comparison Of File Archivers
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Exploring foci of
2021-07-27
Landscape of tissue-specific RNA Editome provides insight into co-regulated and altered gene expression in pigs (<i>Sus-scrofa</i>)
2021-07-27 • Adeyinka Abiola Adetula, Xinhao Fan, Yongsheng Zhang, Yilong Yao, Junyu Yan, Muya Chen, Yijie Tang, Yuwen Liu, Guoqiang Yi, Kui Li, Zhonglin Tang
RNA editing generates genetic diversity in mammals by altering amino acid sequences, miRNA targeting site sequences, influencing the stability of targeted RNAs, and causing changes in gene expression. However, the extent to which RNA editing affect gene expression via modifying miRNA binding site remains unexplored. Here, we first profiled the dynamic A-to-I RNA editome across tissues of Duroc and Luchuan pigs. The RNA editing events at the miRNA binding sites were generated. The biological function of the differe…
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Landscape Photography
English Landscape Garden
Landscape
Landscape Design
Landscape Ecology
Cultural Landscape
The Moral Landscape
Landscape With The Fall Of Icarus
Landscape Painting
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