MV Padma Srivastava
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View article: Patterns and predictors of cancer-associated ischemic stroke
Patterns and predictors of cancer-associated ischemic stroke Open
Objectives: Cancer-associated stroke (CAS) represents a unique ischemic stroke subtype with distinct mechanisms and poor prognosis. Our study aimed to evaluate CAS patient demographics, stroke patterns, and prognostic factors with a focus …
View article: Subacute Sclerosing Panencephalitis: A Clinical, Radiological, and Outcome Study of 144 Cases
Subacute Sclerosing Panencephalitis: A Clinical, Radiological, and Outcome Study of 144 Cases Open
Background and Objectives: Subacute sclerosing panencephalitis (SSPE) is a progressive encephalitis caused by persistent measles virus infection and is mostly described as small case series in literature. We aimed to describe the clinical …
View article: Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention
Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention Open
Background and Objectives: Intracerebral hemorrhage (ICH) is associated with high mortality and morbidity. Uncertainty still exists regarding the benefit of surgery in the management of supratentorial spontaneous ICH (sICH), especially of …
View article: Sociodemographic and risk factor analysis of the SMRUTHI India: a cohort of at risk elderly Indians for primary prevention of dementia
Sociodemographic and risk factor analysis of the SMRUTHI India: a cohort of at risk elderly Indians for primary prevention of dementia Open
Background Around 40% of dementia cases can be prevented or delayed by modifying the risk factors. The SMRUTHI INDIA study will be conducted to establish a trial‐ready cohort of elderly Indians who are at high risk of developing dementia. …
View article: Multimodal Care Bundle Approach for Primary Prevention of Dementia in an Indian Cohort (SMRUTHI‐India)
Multimodal Care Bundle Approach for Primary Prevention of Dementia in an Indian Cohort (SMRUTHI‐India) Open
Background The SMRUTHI‐India is a multimodal multisite intervention trial among the “at‐risk” elderly population of India, in a cohort randomized controlled manner for the prevention of Dementia. This study intends to introduce and present…
View article: An Institutional Perspective on the Number of Stent Retriever Pass and Rate of Recanalization in Mechanical Thrombectomy for Acute Ischemic Stroke: When to Stop?
An Institutional Perspective on the Number of Stent Retriever Pass and Rate of Recanalization in Mechanical Thrombectomy for Acute Ischemic Stroke: When to Stop? Open
Background and purpose: Mechanical thrombectomy is the standard treatment modality for flow restoration in acute ischemic stroke. In cases of persistent occlusion, the optimal number of retrieval attempts before considering procedure termi…
View article: RE-OPEN: Randomised trial of biosimilar TNK versus TPA during endovascular therapy for acute ischaemic stroke due to large vessel occlusions
RE-OPEN: Randomised trial of biosimilar TNK versus TPA during endovascular therapy for acute ischaemic stroke due to large vessel occlusions Open
Rationale Rapid and timely treatment with intravenous thrombolysis and endovascular treatment (EVT) in patients with acute ischaemic stroke (AIS) and large vessel occlusion (LVO) significantly improves patient outcomes. Bridging therapy is…
View article: Strategic Multimodal Intervention in at‐risk Elderly Indians for Prevention of Dementia (SMRUTHI INDIA): A cohort multiple randomised controlled trial (cmRCT)
Strategic Multimodal Intervention in at‐risk Elderly Indians for Prevention of Dementia (SMRUTHI INDIA): A cohort multiple randomised controlled trial (cmRCT) Open
Background The major burden of dementia will be falling on Low and middle‐income countries in the next few decades. One of the major strategies to counter the rise in dementia burden is primary prevention, especially in at‐risk elderly ind…
View article: Optical Genome Mapping for the Molecular Diagnosis of Facioscapulohumeral Muscular Dystrophy: Advancement and Challenges
Optical Genome Mapping for the Molecular Diagnosis of Facioscapulohumeral Muscular Dystrophy: Advancement and Challenges Open
Facioscapulohumeral muscular dystrophy (FSHD) is the second most common muscular dystrophy in adults, and it is associated with local D4Z4 chromatin relaxation, mostly via the contraction of the D4Z4 macrosatellite repeat array on chromoso…
View article: Use of Social Media in Stroke: A Systematic Review
Use of Social Media in Stroke: A Systematic Review Open
Background: Stroke is a leading cause of death and disability globally. Over the last decade, digital health and related technology has emerged as a useful adjunct in the management of persons with stroke, particularly with the development…
View article: Collateral Circulation- Evolving from Time Window to Tissue Window
Collateral Circulation- Evolving from Time Window to Tissue Window Open
Cerebral collateral circulation refers to the auxiliary vascular structures which compensate cerebral blood flow when it has been compromised due to stenosis or occlusion of the principal supplying arteries. They play a vital role in susta…
View article: Quantifying Quality of Life after Stroke
Quantifying Quality of Life after Stroke Open
How do you define the quality of life? As a measure of how easily and successfully one can accomplish activities of daily living? Eating, bathing, dressing, walking, talking, etc.? Which on an ordinary day are taken for granted as a "norma…
View article: Machine Learning Based Reanalysis of Clinical Scores for Distinguishing Between Ischemic and Hemorrhagic Stroke in Low Resource Setting
Machine Learning Based Reanalysis of Clinical Scores for Distinguishing Between Ischemic and Hemorrhagic Stroke in Low Resource Setting Open
BACKGROUND Identification of stroke and classifying them as ischemic and hemorrhagic type using clinical scores alone faces two unaddressed issues. One pertains to over-estimation of performance of scores and the other involves class imbal…
View article: Cerebral Venous Sinus Thrombosis Presenting with Features of Raised Intracranial Tension and En Plaque Meningeal Thickening; A Case Report
Cerebral Venous Sinus Thrombosis Presenting with Features of Raised Intracranial Tension and En Plaque Meningeal Thickening; A Case Report Open
View article: Early Post-Stroke Seizures in Acute Ischemic Stroke
Early Post-Stroke Seizures in Acute Ischemic Stroke Open
Introduction: Stroke is the most common cause of epilepsy in the adult population. Post-stroke seizures (PSSs) are classified into early-onset seizures (ES) and late-onset (LS). ES can significantly affect the clinical outcome and occurren…
View article: Steroid responsive acute isolated ophthalmoplegia: A rare presentation of anti-GQ1b antibodies syndrome
Steroid responsive acute isolated ophthalmoplegia: A rare presentation of anti-GQ1b antibodies syndrome Open
View article: Contributing factors which led to relapse of tobacco-seeking behaviour among stroke survivors, in a selected tertiary care hospital, New Delhi
Contributing factors which led to relapse of tobacco-seeking behaviour among stroke survivors, in a selected tertiary care hospital, New Delhi Open
Background: The outcome of treatment of stroke depends on removal of modifiable risk factors, such as stopping tobacco seeking behavior which is important factor to prevent reoccurrence of stroke. Aim: To identify contributory factors and …
View article: Polymyositis with too many associations: A paraneoplastic syndrome
Polymyositis with too many associations: A paraneoplastic syndrome Open
Sir, Polymyositis is characterized by symmetrical proximal weakness. Asymmetry and associated neuropathy are rare. It may be associated with interstitial lung disease (ILD), and a paraneoplastic association is known as well. The disease is…
View article: TIA as acute cerebrovascular syndrome
TIA as acute cerebrovascular syndrome Open