Mychajlo S. Kosyk
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View article: Three-Dimensional Assessment of Orbital Contours and Their Significance in Forehead Feminization
Three-Dimensional Assessment of Orbital Contours and Their Significance in Forehead Feminization Open
View article: D139. Development of an AI-Based Predictive Model for Septic Wrist and a Risk Assessment Tool
D139. Development of an AI-Based Predictive Model for Septic Wrist and a Risk Assessment Tool Open
PURPOSE: This study aimed to create a septic wrist AI prediction model and develop a score-based risk assessment tool. METHODS: An IRB-approved retrospective review was conducted on patients with a presumed septic wrist diagnosis (2003-202…
View article: 85. Development Of An AI-Based Predictive Model For Septic Wrist And A Risk Assessment Tool
85. Development Of An AI-Based Predictive Model For Septic Wrist And A Risk Assessment Tool Open
Purpose: The existing diagnostic criteria for septic wrist are non-specific, subjecting patients with non-infectious etiologies to surgical morbidity. This study aimed to create a septic wrist AI prediction model and develop a score-based …
View article: Septic Wrist or Wrist Inflammation? A 19-Year Review
Septic Wrist or Wrist Inflammation? A 19-Year Review Open
BACKGROUND: The existing diagnostic criteria for septic wrist are non-specific and patients with non-infectious etiologies risk undergoing unnecessary surgeries. This study aimed to identify predictive parameters to differentiate septic wr…
View article: Facial Scars: Do Position and Orientation Matter?
Facial Scars: Do Position and Orientation Matter? Open
Background: This study tested the core tenets of how facial scars are perceived by characterizing layperson response to faces with scars. The authors predicted that scars closer to highly viewed structures of the face (i.e., upper lip and …
View article: A Retrospective Cohort Study of 5-Year Aesthetic Outcomes: Fronto-orbital Distraction Osteogenesis Versus Fronto-orbital Advancement & Remodeling
A Retrospective Cohort Study of 5-Year Aesthetic Outcomes: Fronto-orbital Distraction Osteogenesis Versus Fronto-orbital Advancement & Remodeling Open
INTRODUCTION: Unicoronal craniosynostosis (UCS) phenotypically presents with ipsilateral frontal and parietal bone flattening, supraorbital rim elevation and recession, temporal retrusion, palpebral fissure widening, and vertical orbital d…
View article: 8. LONGITUDINAL OUTCOMES IN MIDFACIAL GROWTH AND SPEECH FOLLOWING FURLOW DOUBLE-OPPOSING Z-PALATOPLASTY: A 30-YEAR RETROSPECTIVE
8. LONGITUDINAL OUTCOMES IN MIDFACIAL GROWTH AND SPEECH FOLLOWING FURLOW DOUBLE-OPPOSING Z-PALATOPLASTY: A 30-YEAR RETROSPECTIVE Open
PURPOSE: The purpose of this study was to evaluate the long-term outcomes of midfacial growth and speech following modified Furlow palatoplasty over a 15-year period. METHODS: A retrospective review was performed of subjects undergoing mod…
View article: P70. INTRACRANIAL PRESSURE PATTERNS IN CHILDREN WITH SAGITTAL CRANIOSYNOSTOSIS
P70. INTRACRANIAL PRESSURE PATTERNS IN CHILDREN WITH SAGITTAL CRANIOSYNOSTOSIS Open
PURPOSE: Elevated intracranial pressure (ICP) in sagittal craniosynostosis has a wide spectrum of reported incidence, and patterns are not well understood across infancy and childhood. Characterizing the natural history of ICP in this popu…
View article: PC23. PEDIATRIC OMPHALOCELE REPAIR: A 26-YEAR SINGLE SURGEON CONSECUTIVE CASE SERIES
PC23. PEDIATRIC OMPHALOCELE REPAIR: A 26-YEAR SINGLE SURGEON CONSECUTIVE CASE SERIES Open
PURPOSE: The purpose of this study was to analyze long-term outcomes following pediatric omphalocele repair. METHODS: A retrospective review was performed of all consecutive subjects undergoing pediatric omphalocele repair between 1994 and…
View article: Abstracts from the American Society of Pediatric Neurosurgeons Virtual Meeting
Abstracts from the American Society of Pediatric Neurosurgeons Virtual Meeting Open
Background/Purpose: Next generation sequencing technologies have permitted a molecular understanding of the patho-etiology of non-syndromic craniosynostosis (NSC), however the underpinnings of the subtle neurocognitive deficits observed in…
View article: Minimally Invasive Endoscopic-assisted Anterior Cranial Vault Fronto-orbital Distraction Osteogenesis
Minimally Invasive Endoscopic-assisted Anterior Cranial Vault Fronto-orbital Distraction Osteogenesis Open
INTRODUCTION: Distraction osteogenesis of the cranial vault has been established as a reliable and safe method for achieving increase in intracranial volume and improvement in head shape in patients with craniosynostosis. Similarly, endosc…
View article: Optical Coherence Tomography for Assessment of Elevated Intracranial Pressure in Sagittal Craniosynostosis
Optical Coherence Tomography for Assessment of Elevated Intracranial Pressure in Sagittal Craniosynostosis Open
INTRODUCTION: Children with early diagnosis of isolated sagittal craniosynostosis are candidates for spring-mediated cranioplasty or endoscopic-assisted strip craniectomy. Neurocognitive developmental differences are seen in some children …
View article: Surgical and Nonsurgical Factors Associated with Salvaging Exposed VEPTR Hardware
Surgical and Nonsurgical Factors Associated with Salvaging Exposed VEPTR Hardware Open
BACKGROUND: Vertical expandable prosthetic titanium rib (VEPTR) devices were designed to treat childhood scoliosis and thoracic insufficiency syndrome, but present a profound subcutaneous hardware burden. It remains unknown whether certain…
View article: Genomic Findings in Bone Blood Paired DNA Comparison of Nonsyndromic Craniosynostosis
Genomic Findings in Bone Blood Paired DNA Comparison of Nonsyndromic Craniosynostosis Open
OBJECTIVE: The purpose of this study is to elucidate genetic variants contributing to nonsyndromic craniosynostosis by comparing samples from abnormally fused bones, unaffected bones, and parent saliva, to those from patient peripheral who…
View article: Sphenoid Wing Dysplasia in the Absence of Neurofibromatosis: Diagnosis and Management of a Novel Phenotype
Sphenoid Wing Dysplasia in the Absence of Neurofibromatosis: Diagnosis and Management of a Novel Phenotype Open
Summary: Congenital sphenoid wing dysplasia is one of the major diagnostic criteria for neurofibromatosis type 1, and is often considered pathognomonic for the disease. Between 5% and 12% of neurofibromatosis type 1 cases have evidence of …
View article: Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells
Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells Open
The PLR in severe LCA patients likely represents the activation of the melanopic circuit in isolation from rod and cone input. Knowledge of the properties of the human melanopic PLR allows not only comparison to those in animal models but …
View article: Human Melanopic Pupillary Responses Isolated from Outer Retinal Photoreceptor Input in LCA Patients with Severe Vision Loss
Human Melanopic Pupillary Responses Isolated from Outer Retinal Photoreceptor Input in LCA Patients with Severe Vision Loss Open
View article: AAV-mediated Knockdown and Replacement of Rhodopsin Protects Rods in a Canine Model of RHO-ADRP
AAV-mediated Knockdown and Replacement of Rhodopsin Protects Rods in a Canine Model of RHO-ADRP Open
View article: Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations
Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations Open
View article: Outcome Measures for Clinical Trials of Leber Congenital Amaurosis Caused by the Intronic Mutation in the <i>CEP290</i> Gene
Outcome Measures for Clinical Trials of Leber Congenital Amaurosis Caused by the Intronic Mutation in the <i>CEP290</i> Gene Open
Efficacy would be a quantitative change in foveal cone function and possibly distal laminar structure. FST provides a subjective photoreceptor-based outcome; OCT and NIR-RAFI can assess photoreceptor and RPE structure. TPLR and OCI can pro…
View article: Overlap of abnormal photoreceptor development and progressive degeneration in Leber congenital amaurosis caused by<i>NPHP5</i>mutation
Overlap of abnormal photoreceptor development and progressive degeneration in Leber congenital amaurosis caused by<i>NPHP5</i>mutation Open
Ciliary defects can result in severe disorders called ciliopathies. Mutations in NPHP5 cause a ciliopathy characterized by severe childhood onset retinal blindness, Leber congenital amaurosis (LCA), and renal disease. Using the canine NPHP…
View article: Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease
Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease Open
Significance Corrective gene therapies for inherited retinal degenerations are being developed with the expectation that even patients in later stages of the disease will benefit from such intervention. Evidence in animal models for a resc…