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View article: Placental Growth Factor Led Management of the Small for Gestational Age Fetus: Randomised Controlled Feasibility Study
Placental Growth Factor Led Management of the Small for Gestational Age Fetus: Randomised Controlled Feasibility Study Open
Objective To determine the feasibility of a trial investigating the optimal timing for the birth of women with a suspected late preterm and term SGA baby using either angiogenic biomarker‐led care or standard care. Design A mixed methods s…
View article: What Should Be Discussed When Considering a Vaginal Birth? A Delphi Consensus Study
What Should Be Discussed When Considering a Vaginal Birth? A Delphi Consensus Study Open
Objective Spontaneous vaginal births are often the presumed choice, representing 45% of UK births. However, information about benefits and risks is inconsistently given, impacting decision‐making and experience. A Core Information Set (CIS…
View article: Butterflies of Franklyn Park, and species diversity in the Mariepskop area, Mpumalanga Province, South Africa
Butterflies of Franklyn Park, and species diversity in the Mariepskop area, Mpumalanga Province, South Africa Open
The Mariepskop Mountain and its associated forests have been a favourite destination for Lepidoptera collectors and researchers alike for many decades. Nestled at the foot of the mountain where the forest gives way to woodland savanna is a…
View article: The PRECISION study protocol: Can cervical stiffness in the second trimester predict preterm birth in high-risk singleton pregnancies? A feasibility, cohort study
The PRECISION study protocol: Can cervical stiffness in the second trimester predict preterm birth in high-risk singleton pregnancies? A feasibility, cohort study Open
Background Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality. More than 13 million babies are affected globally every year and PTB will contribute to over 900,000 deaths. In the UK, PTB affects 8% of pregnancies an…
View article: The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? a feasibility, cohort study
The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? a feasibility, cohort study Open
Background Induction of labour (IOL) is a common obstetric intervention in the UK, affecting up to 33% of deliveries. IOL aims to achieve a vaginal delivery prior to spontaneous onset of labour to prevent harm from ongoing pregnancy compli…
View article: The efficacy of sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction: the STRIDER RCT
The efficacy of sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction: the STRIDER RCT Open
Background Severe early-onset intrauterine growth restriction is associated with stillbirth, neonatal death and neurodevelopmental impairment. There is no treatment for intrauterine growth restriction with timely delivery being the only ma…
View article: Study Protocol. The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? A feasibility, cohort study
Study Protocol. The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? A feasibility, cohort study Open
Background Induction of labour (IOL) is a common obstetric intervention in the UK, affecting up to 33% of deliveries. IOL aims to achieve a vaginal delivery prior to spontaneous onset of labour to prevent harm from ongoing pregnancy compli…
View article: The impact of gestational diabetes and gestational hypertension on future cardiovascular events: A nationwide cross-sectional cohort study
The impact of gestational diabetes and gestational hypertension on future cardiovascular events: A nationwide cross-sectional cohort study Open
Women with a history of both GH and GDM are at a 23-fold increased risk of myocardial infarction within the first 5 years of their postnatal lives.
View article: FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy – protocol for a prospective multicentre mixed-methods feasibility study
FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy – protocol for a prospective multicentre mixed-methods feasibility study Open
Introduction Selective fetal growth restriction (sFGR) in monochorionic twin pregnancy, defined as an estimated fetal weight (EFW) of one twin <10th centile and EFW discordance ≥25%, is associated with stillbirth and neurodisability for bo…
View article: Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study
Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study Open
Objectives As part of the FERN feasibility study, this qualitative research aimed to explore parents’ and clinicians’ views on the acceptability, feasibility and design of a randomised controlled trial (RCT) of active intervention versus e…
View article: Diagnosis and management of selective fetal growth restriction in monochorionic twin pregnancies: A cross‐sectional international survey
Diagnosis and management of selective fetal growth restriction in monochorionic twin pregnancies: A cross‐sectional international survey Open
Objective To identify current practices in the management of selective fetal growth restriction (sFGR) in monochorionic diamniotic (MCDA) twin pregnancies. Design Cross‐sectional survey. Setting International. Population Clinicians involve…
View article: Neurodevelopmental outcomes at 2 years in children who received sildenafil therapy in utero: The <scp>STRIDER randomised controlled trial</scp>
Neurodevelopmental outcomes at 2 years in children who received sildenafil therapy in utero: The <span>STRIDER randomised controlled trial</span> Open
Objective Severe early‐onset fetal growth restriction (FGR) causes stillbirth, neonatal death and neurodevelopmental impairment. Poor maternal spiral artery remodelling maintains vasoactive responsiveness but is susceptible to treatment wi…
View article: Repeat Placental Growth Factor-Based Testing in Women With Suspected Preterm Preeclampsia: A Stratified Analysis of the PARROT-2 Trial
Repeat Placental Growth Factor-Based Testing in Women With Suspected Preterm Preeclampsia: A Stratified Analysis of the PARROT-2 Trial Open
BACKGROUND: PlGF (placental growth factor)-based testing reduces severe maternal adverse outcomes. Repeat PlGF-based testing is not associated with improved perinatal or maternal outcomes. This planned secondary analysis aimed to determine…
View article: Low Iodine Nutrition Knowledge in Chinese Breastfeeding Women despite Adequate Iodine Status
Low Iodine Nutrition Knowledge in Chinese Breastfeeding Women despite Adequate Iodine Status Open
There has been a scarcity of evidence about iodine nutrition knowledge among women during pregnancy and lactation. The aim of this study was to determine women’s iodine knowledge and the relationship between knowledge and iodine status dur…
View article: The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women
The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women Open
Breast milk iodine concentration (BMIC) is a promising indicator of iodine status in lactating women. However, there are limited data on its usefulness to reflect maternal iodine deficiency. Therefore, the aim of our study was to assess io…
View article: Vaginal birth core information set: study protocol for a Delphi study to achieve a consensus on a ‘core information set’ for vaginal birth
Vaginal birth core information set: study protocol for a Delphi study to achieve a consensus on a ‘core information set’ for vaginal birth Open
Introduction Studies have shown that women are often underinformed about potential benefits and risks of vaginal birth. This is in contrast to other modes of birth, such as caesarean birth, for which the risks/benefits are often conveyed p…
View article: Interventions affecting the nitric oxide pathway versus placebo or no therapy for fetal growth restriction in pregnancy
Interventions affecting the nitric oxide pathway versus placebo or no therapy for fetal growth restriction in pregnancy Open
Interventions affecting the nitric oxide pathway probably do not seem to influence all-cause (fetal and neonatal) mortality in pregnant women carrying a baby with FGR, although more evidence is needed. The certainty of this evidence is mod…
View article: Effectiveness of dinoprostone gel, misoprostol vaginal insert and dinoprostone vaginal insert for induction of labour in twin pregnancies
Effectiveness of dinoprostone gel, misoprostol vaginal insert and dinoprostone vaginal insert for induction of labour in twin pregnancies Open
Our data suggests that for women with a twin pregnancy considering a planned labour that induction with DG, MVI and DVI appear to be equally safe and effective IOL methods. These results should be interpreted with caution due to the study …
View article: Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study – CORRIGENDUM
Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study – CORRIGENDUM Open
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View article: Computerized cardiotocography and Dawes–Redman criteria: how should we interpret criteria not met?
Computerized cardiotocography and Dawes–Redman criteria: how should we interpret criteria not met? Open
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View article: Pregnancy-Related Complications and Incidence of Atrial Fibrillation: A Systematic Review
Pregnancy-Related Complications and Incidence of Atrial Fibrillation: A Systematic Review Open
Pregnancy-related complications are associated with a higher risk of various incident cardiovascular diseases, but their specific potential relationship with incident atrial fibrillation (AF) is less clear. This systematic review summarise…
View article: Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study
Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study Open
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View article: Nanomedicine strategies to improve therapeutic agents for the prevention and treatment of preterm birth and future directions
Nanomedicine strategies to improve therapeutic agents for the prevention and treatment of preterm birth and future directions Open
This review outlines the importance of improving the treatment of preterm birth, summarises the use of nanomedicines for the delivery of active pharmaceutical ingredients and discusses the opportunities/challenges for enhancing future pati…
View article: Low iodine knowledge in a group of Chinese breastfeeding women with adequate iodine status
Low iodine knowledge in a group of Chinese breastfeeding women with adequate iodine status Open
An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button.
View article: A nationwide cohort study on the impact of gestational diabetes on future cardiovascular events
A nationwide cohort study on the impact of gestational diabetes on future cardiovascular events Open
Background The link between hypertensive disease in pregnancy and future cardiovascular events is well established, as is the increased risk of developing type 2 diabetes mellitus after gestational diabetes (GDM). What is less well underst…
View article: Pharmacological Interventions in Labor and Delivery
Pharmacological Interventions in Labor and Delivery Open
While there is not a wide range of pregnancy-specific drugs, there are some very specific high-risk areas of obstetric care for which unique pharmacological approaches have been established. In preterm birth, labor induction and augmentati…
View article: Foetal loss after chorionic villus sampling and amniocentesis in twin pregnancies: A multicentre retrospective cohort study
Foetal loss after chorionic villus sampling and amniocentesis in twin pregnancies: A multicentre retrospective cohort study Open
Objective We aimed to determine foetal losses for DCDA and MCDA twins following transabdominal CVS or amniocentesis performed <22+ 0 weeks. Methods Retrospective cohort study conducted in the UK and Belgium 01/01/00–01/06/20. Cases with un…