Explanipedia

Counterion-Enabled Divergent Reactivity in Dinuclear Gold Photoredox Catalysis Open

Mahesh Bhagwan Thoke, Anupam Das, Deep S. Kulkarni, Nitin T. Patil · 2025

Tuning the electronics of photocatalysts is crucial for controlling the reactivity pathways in photoredox catalysis. While the key approaches like ligand engineering and donor-acceptor modulation are crucial, they invariably require multis…

Gold-Mediated Chemistry Special Issue Open

Belén Martı́n-Matute, Nitin T. Patil, Marı́a Méndez, Xiaodong Shi · 2025

Bidentate (P^N) Au(<span>iii</span>)–azide complexes: synthesis and reductive elimination studies Open

Urvashi Urvashi, Nitin T. Patil · 2025

Herein, we report the synthesis and characterization of novel (P^N) aryl Au( iii )–azide complexes.

Ligand‐Enabled Gold‐Catalyzed Cyanation of Organohalides Open

Anil Kumar, Nandita Bhattacharya, Manoj V. Mane, Nitin T. Patil · 2024

Herein, we disclose the first report on gold‐catalyzed C(sp 2 )‐CN cross‐coupling reaction by employing a ligand‐enabled Au(I)/Au(III) redox catalysis. This transformation utilizes acetone cyanohydrin as a nucleophilic cyanide source to co…

Ligand‐Enabled Gold‐Catalyzed Cyanation of Organohalides Open

Anil Kumar, Nandita Bhattacharya, Manoj V. Mane, Nitin T. Patil · 2024

Herein, we disclose the first report on gold‐catalyzed C(sp 2 )‐CN cross‐coupling reaction by employing a ligand‐enabled Au(I)/Au(III) redox catalysis. This transformation utilizes acetone cyanohydrin as a nucleophilic cyanide source to co…

Gold-Catalyzed Migratory Insertion of Alkynes Open

Avishek Das, Biswajit Biswas, Vincent Gandon, Nitin T. Patil · 2024

Herein, for the first time, we disclose the migratory insertion of alkynes into Au(III)‒C bonds in a catalytic fashion. Experimental results clearly suggest that the migratory insertion pathway predominates over the π-activation pathway - …

Gold‐Catalyzed Alkoxy‐Carbonylation of Aryl and Vinyl Iodides Open

Vivek W. Bhoyare, Asish Bera, Vincent Gandon, Nitin T. Patil · 2024

Herein, for the first time, we disclose the gold‐catalyzed alkoxy‐carbonylation of aryl and vinyl iodides utilizing ligand‐enabled Au(I)/Au(III) redox catalysis. The present methodology is found to be general, efficient, employs mild react…

Gold-Catalyzed 1,2-Carboxyarylation of Alkenes Open

Tanmayee Nanda, Avishek Das, Prafulla Bera, Nitin T. Patil · 2024

Herein, we have disclosed the gold-catalyzed 1,2-carboxyarylation of alkenes through the ligand enabled Au(I)/Au(III) catalysis. Unlike other approaches for arylative functionalization of C-C multiple bonds that involve the use of strong n…

Gold-Catalyzed Migratory Insertion of Alkynes Open

Avishek Das, Biswajit Biswas, Vincent Gandon, Nitin T. Patil · 2024

Herein, we disclose the gold-catalyzed annulation reaction of 2-iodobiphenyls with alkynes, leading to the formation of phenanthrene derivatives. The crucial aspect of this reaction lies in the catalytic migratory insertion of alkynes into…

Early Detection of Breast Cancer using Deep Learning in Mammograms Open

Rashmi Gudur, Nitin T. Patil, Shridhar Thorat · 2024

Breast cancer still poses a serious threat to world health, needing creative approaches to early identification in order to improve patient outcomes. This study investigates the potential of deep learning methods to improve the precision a…

Gold-Catalyzed Alkoxy-Carbonylation of Organohalides Open

Vivek W. Bhoyare, Asish Bera, Vincent Gandon, Nitin T. Patil · 2024

Herein, for the first time, we disclose the gold-catalyzed alkoxy-carbonylation of organohalides utilizing ligand-enabled Au(I)/Au(III) redox catalysis. The present methodology is found to be general, efficient, employs mild reaction condi…

CCDC 2290838: Experimental Crystal Structure Determination Open

Urvashi Urvashi, Sampoorna Mishra, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2246572: Experimental Crystal Structure Determination Open

Vivek W. Bhoyare, Akash G. Tathe, Vincent Gandon, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2254613: Experimental Crystal Structure Determination Open

Vivek W. Bhoyare, Akash G. Tathe, Vincent Gandon, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Gold-Catalyzed Alkenylation and Arylation of Phosphorothioates Open

Urvashi Urvashi, Sampoorna Mishra, Nitin T. Patil · 2023

Reported herein is the gold-catalyzed alkenylation and arylation of phosphorothioates using alkenyl and aryl iodides. The facile transmetalation between Ag-sulfur complex and Au(III) intermediate formed after oxidative addition is the key …

Unlocking the Chain-Walking Process in Gold Catalysis Open

Vivek W. Bhoyare, Akash G. Tathe, Vincent Gandon, Nitin T. Patil · 2023

The successful realization of gold-catalyzed chain-walking reactions, facilitated by ligand-enabled Au(I)/Au(III) redox catalysis, has been reported for the first time. This breakthrough has led to the development of gold-catalyzed annulat…

Electrochemical Gold‐Catalyzed 1,2‐Difunctionalization of C−C Multiple Bonds** Open

Anil Kumar, Khyati Shukla, Salman Ahsan, Amit Paul, Nitin T. Patil · 2023

Herein, we disclose the first report of 1,2‐difunctionalization of C−C multiple bonds using electrochemical gold redox catalysis. By adopting the electrochemical strategy, the inherent π‐activation and cross‐coupling reactivity of gold cat…

Electrochemical Gold‐Catalyzed 1,2‐Difunctionalization of C−C Multiple Bonds** Open

Anil Kumar, Khyati Shukla, Salman Ahsan, Amit Paul, Nitin T. Patil · 2023

Herein, we disclose the first report of 1,2‐difunctionalization of C−C multiple bonds using electrochemical gold redox catalysis. By adopting the electrochemical strategy, the inherent π‐activation and cross‐coupling reactivity of gold cat…

CCDC 2244813: Experimental Crystal Structure Determination Open

Nitin T. Patil, Shashank P. Sancheti, Yukta Singh, Manoj V. Mane · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2261141: Experimental Crystal Structure Determination Open

Nitin T. Patil, Shashank P. Sancheti, Yukta Singh, Manoj V. Mane · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2244819: Experimental Crystal Structure Determination Open

Nitin T. Patil, Shashank P. Sancheti, Yukta Singh, Manoj V. Mane · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Electrochemical Gold-Catalyzed 1,2-Difunctionalization of C–C Multiple Bonds Open

Anil Kumar, Khyati Shukla, Salman Ahsan, Amit Paul, Nitin T. Patil · 2023

Herein, we disclose the first report of 1,2-difunctionalization of C-C multiple bonds using electrochemical redox gold catalysis. By adopting the electrochemical strategy, the inherent π-activation and cross-coupling reactivity of gold cat…

Gold-Catalyzed Interrupted Relay Heck Reaction Open

Vivek W. Bhoyare, Akash G. Tathe, Vincent Gandon, Nitin T. Patil · 2023

Herein, we disclose the gold-catalyzed interrupted relay Heck reaction successfully demonstrating the implementation of a chain-walking process for the first time in a catalytic fashion. The reaction involves the merging of three distinct …

Gold-Catalyzed 1,2-Dicarbofunctionalization of Alkynes Open

Nitin T. Patil, Shashank P. Sancheti, Yukta Singh, Manoj V. Mane · 2023

Herein, we report the first gold-catalyzed 1,2-dicarbofunctionalization of alkynes using organohalides as non-prefunctionalized coupling partners. The mechanism of the reaction involves an oxidative addition/π-activation mechanism, in cont…

CCDC 2218105: Experimental Crystal Structure Determination Open

Shashank P. Sancheti, Dibya Jyoti Mondal, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2218000: Experimental Crystal Structure Determination Open

Shashank P. Sancheti, Dibya Jyoti Mondal, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2195866: Experimental Crystal Structure Determination Open

Vivek W. Bhoyare, E. Daiann Sosa Carrizo, Chetan C. Chintawar, Vincent Gandon, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2195871: Experimental Crystal Structure Determination Open

Vivek W. Bhoyare, E. Daiann Sosa Carrizo, Chetan C. Chintawar, Vincent Gandon, Nitin T. Patil · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Gold Catalysis: A New Contender for Cross-Coupling Reactions with Aryl Halides Open

Vaibhav Bedi, Puja K. Mahajan, Nitin T. Patil · 2023

Cross-coupling reactions of aryl halides catalyzed by transition metals such as Pd, Ni, Cu etc have shown to be effective tools for the generation of carbon–carbon and carbon–heteroatom bonds. However, because of the difficulties associate…

Ligand-Enabled Gold-Catalyzed C(sp2)–O Cross-Coupling Reactions Open

Nitin T. Patil, Avishek Das · 2023

Reported herein is a ligand-enabled gold-catalyzed C(sp2)-O cross-coupling reaction of aryl iodides and aliphatic alcohols. The synthesis of a variety of aryl alkyl ethers including complex biomolecules and various medicinally relevant mot…

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