N. Chug
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View article: Quality control of plastic scintillators for the total-body J-PET scanner
Quality control of plastic scintillators for the total-body J-PET scanner Open
The construction of the total-body Jagiellonian positron emission tomography scanner requires component verification before detector assembly. The purpose of this research is to verify the quality of BC-408 plastic scintillators with dimen…
View article: μPPET: Investigating the Muon Puzzle with J-PET Detectors
μPPET: Investigating the Muon Puzzle with J-PET Detectors Open
The μPPET [mu(μ)on Probe with J-PET] project aims to investigate the “Muon Puzzle” seen in cosmic ray air showers. This puzzle arises from the observation of a significantly larger number of muons on Earth’s surface than that predicted by …
View article: Nonmaximal entanglement of photons from positron-electron annihilation demonstrated using a plastic PET scanner
Nonmaximal entanglement of photons from positron-electron annihilation demonstrated using a plastic PET scanner Open
In state-of-the-art positron emission tomography (PET), information about annihilation photon polarization is unavailable. Here, we present a PET scanner built from plastic scintillators, where annihilation photons primarily interact via t…
View article: Realistic total‐body J‐PET geometry optimization: Monte Carlo study
Realistic total‐body J‐PET geometry optimization: Monte Carlo study Open
Background Total‐body (TB) Positron Emission Tomography (PET) is one of the most promising medical diagnostics modalities, opening new perspectives for personalized medicine, low‐dose imaging, multi‐organ dynamic imaging or kinetic modelin…
View article: First Positronium Imaging Using <sup>44</sup>Sc With the J-PET Scanner: a Case Study on the NEMA-Image Quality Phantom
First Positronium Imaging Using <sup>44</sup>Sc With the J-PET Scanner: a Case Study on the NEMA-Image Quality Phantom Open
Positronium Lifetime Imaging (PLI), an emerging extension of conventional positron emission tomography (PET) imaging, offers a novel window for probing the submolecular properties of biological tissues by imaging the mean lifetime of the p…
View article: Development of the normalization method for the first large field-of-view plastic-based PET Modular scanner
Development of the normalization method for the first large field-of-view plastic-based PET Modular scanner Open
In positron emission tomography acquisition (PET), sensitivity along a line of response can vary due to crystal geometrical arrangements in the scanner and/or detector inefficiencies, leading to severe artefacts in the reconstructed image.…
View article: Positronium image of the human brain in vivo
Positronium image of the human brain in vivo Open
Positronium is abundantly produced within the molecular voids of a patient’s body during positron emission tomography (PET). Its properties dynamically respond to the submolecular architecture of the tissue and the partial pressure of oxyg…
View article: Nanoporosity imaging by positronium lifetime tomography
Nanoporosity imaging by positronium lifetime tomography Open
Positron Annihilation Lifetime Spectroscopy (PALS) is a well-established non-destructive technique used for nanostructural characterization of porous materials. It is based on the annihilation of a positron and an electron. Mean positron l…
View article: Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology:A Simulation Study
Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology:A Simulation Study Open
The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment …
View article: Exploring the limits of CPT symmetry in ortho-positronium decays with J-PET
Exploring the limits of CPT symmetry in ortho-positronium decays with J-PET Open
The CPT symmetry is one of the most fundamental symmetries in physics. Any violation of this symmetry would have profound implications for our understanding of the universe. In this study, we report the CPT symmetry tests in 3$\\gamma$ dec…
View article: First positronium image of the human brain<i>in vivo</i>
First positronium image of the human brain<i>in vivo</i> Open
Positronium, an unstable atom consisting of an electron and a positron, is abundantly produced within the molecular voids of a patient’s body during positron emission tomography (PET) diagnosis. Its properties, such as its average lifetime…
View article: Improved test of CPT invariance in ortho-positronium decays at J-PET
Improved test of CPT invariance in ortho-positronium decays at J-PET Open
Symmetry violation under the combined transformation of charge (C), parity (P), and time reversal (T) in the charged leptonic sector can be sought through the non-vanishing expectation value of certain angular correlation operators that ar…
View article: Discrete symmetries tested at 10−4 precision using linear polarization of photons from positronium annihilations
Discrete symmetries tested at 10−4 precision using linear polarization of photons from positronium annihilations Open
View article: Classification of Signal Events for CPT~Symmetry Studies with J-PET Using Machine Learning Techniques
Classification of Signal Events for CPT~Symmetry Studies with J-PET Using Machine Learning Techniques Open
The deviations from combined Charge, Parity, and Time (CPT) symmetry could indicate the presence of new physics beyond the current theoretical framework. The positronium (Ps), the lightest bound state of an electron–positron pair, offers a…
View article: Feasibility study of positronium imaging with Biograph Vision Quadra and Modular J-PET
Feasibility study of positronium imaging with Biograph Vision Quadra and Modular J-PET Open
Positronium Imaging is gaining interest as a new promising method that may improve the diagnostic specificity of Positron Emission Tomography. Recently, the first ex-vivo and in-vivo positronium lifetime images were demonstrated by means o…
View article: Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators
Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators Open
View article: Feasibility studies for imaging e$^{+}$e$^{-}$ annihilation with modular multi-strip detectors
Feasibility studies for imaging e$^{+}$e$^{-}$ annihilation with modular multi-strip detectors Open
Studies based on imaging the annihilation of the electron (e$^{-}$) and its antiparticle positron (e$^{+}$) open up several interesting applications in nuclear medicine and fundamental research. The annihilation process involves both the d…
View article: Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study
Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study Open
Objective. The Jagiellonian positron emission tomography (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasi…
View article: Modular J-PET with Improved o-Ps Detection Efficiency for CPT Tests
Modular J-PET with Improved o-Ps Detection Efficiency for CPT Tests Open
J-PET is a photon detector built of plastic scintillators, which already has been commissioned for CPT studies in the decays of positronium. In the first experiment, J-PET has achieved a sensitivity to CPT violation at a level of 10−4, and…
View article: Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators
Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators Open
Background: Total-Body imaging offers high sensitivity, single-bed position, and low dose, but high construction costs limit worldwide utilization. This study compares existing and developing tomographs using plastic scintillators via simu…
View article: Efficiency determination of J-PET: first plastic scintillators-based PET scanner
Efficiency determination of J-PET: first plastic scintillators-based PET scanner Open
Background The Jagiellonian Positron Emission Tomograph is the 3-layer prototype of the first scanner based on plastic scintillators, consisting of 192 half-metre-long strips with readouts at both ends. Compared to crystal-based detectors,…
View article: Comparative studies of plastic scintillator strips with high technical attenuation length for the total-body J-PET scanner
Comparative studies of plastic scintillator strips with high technical attenuation length for the total-body J-PET scanner Open
View article: Feasibility of the J-PET to monitor range of therapeutic proton beams
Feasibility of the J-PET to monitor range of therapeutic proton beams Open
Objective: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: The Monte Carlo simulation studies with GATE and…
View article: Modular J-PET with Improved o-Ps Detection Efficiency for CPT Tests
Modular J-PET with Improved o-Ps Detection Efficiency for CPT Tests Open
J-PET is a photon detector built of plastic scintillators, which already has been commissioned for CPT studies in the decays of positronium. In the first experiment, J-PET has achieved a sensitivity to CPT violation at a level of 10^{-4}, …
View article: TOF MLEM Adaptation for the Total-Body J-PET With a Realistic Analytical System Response Matrix
TOF MLEM Adaptation for the Total-Body J-PET With a Realistic Analytical System Response Matrix Open
We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is applica…
View article: J-PET detection modules based on plastic scintillators for performing studies with positron and positronium beams
J-PET detection modules based on plastic scintillators for performing studies with positron and positronium beams Open
The J-PET detector, which consists of inexpensive plastic scintillators, has demonstrated its potential in the study of fundamental physics. In recent years, a prototype with 192 plastic scintillators arranged in 3 layers has been optimize…
View article: Transformation of PET raw data into images for event classification using convolutional neural networks
Transformation of PET raw data into images for event classification using convolutional neural networks Open
In positron emission tomography (PET) studies, convolutional neural networks (CNNs) may be applied directly to the reconstructed distribution of radioactive tracers injected into the patient's body, as a pattern recognition tool. Nonethele…
View article: Realistic Total-Body J-PET Geometry Optimization -- Monte Carlo Study
Realistic Total-Body J-PET Geometry Optimization -- Monte Carlo Study Open
Total-Body PET is one of the most promising medical diagnostics modalities. The high sensitivity provided by Total-Body technology can be advantageous for novel tomography methods like positronium imaging. Several efforts are ongoing to lo…
View article: Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology: A Simulation Study
Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology: A Simulation Study Open
The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment …
View article: ProTheRaMon—a GATE simulation framework for proton therapy range monitoring using PET imaging
ProTheRaMon—a GATE simulation framework for proton therapy range monitoring using PET imaging Open
Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). Pro…