Explanipedia

Recognition of Oral Cancer Progression Stages using White Light Imaging Open

Sasidharan Padmaja Divya, Debajyoti Kumar, Ch. Yashwanth, Deepthi Rao · 2025

Oral cancer is the sixth most frequent type of cancer worldwide, and it is one of the main causes of mortality. Although early detection during precancerous phases can greatly increase survival rates, late-stage diagnoses are the cause of …

EFFICACY OF AN AYURVEDIC INTERVENTION AS AN ADJUNCT TO STANDARD CARE IN PREVENTING ACUTE PAIN CRISES IN SICKLE CELL ANEMIA: PROTOCOL OF A RANDOMIZED CONTROLLED TRIAL (Preprint) Open

U R Sekhar Namburi, Priya Thakre, Vaishali Kuchewar, Manish Deshmukh, Kalpana Kachare , et al. · 2025

Efficacy of an Ayurvedic Intervention as an Adjunct to Standard Care in Preventing Acute Pain Crises in Sickle Cell Anemia: Protocol of a Randomized Controlled Trial (Preprint) Open

U R Sekhar Namburi, Priya Thakre, Vaishali Kuchewar, Manish Deshmukh, Kalpana Kachare , et al. · 2025

BACKGROUND Sickle Cell Anemia (SCA) represents a major health concern among the tribal population of India, with frequent acute pain crises significantly compromising the quality of life of the affected individuals. As an inherited disord…

Quantifying changes in steatotic liver disease after bariatric surgery using ultrasound-derived fat fraction Open

Nanda Deepa Thimmappa, Ayman H. Gaballah, Talissa A. Altes, Deepti N Rao, Andrew A. Wheeler , et al. · 2025

Background A noninvasive, readily accessible, and quantitative methods are needed to evaluate changes in hepatic fat over time in patients undergoing bariatric surgery. Purpose To measure the change in ultrasound-derived fat fraction (UDFF…

Predicting Survivability of Cancer Patients with Metastatic Patterns Using Explainable AI Open

Polycarp Nalela, Deepthi Rao, Praveen Kumar Rao · 2025

Cancer remains a leading global health challenge and a major cause of mortality. This study leverages machine learning (ML) to predict the survivability of cancer patients with metastatic patterns using the comprehensive MSK-MET dataset, w…

A scalable tool for analyzing genomic variants of humans using knowledge graphs and graph machine learning Open

Shivika Prasanna, Ajay Kumar, Deepthi Rao, Eduardo J. Simões, Praveen Rao · 2025

Advances in high-throughput genome sequencing have enabled large-scale genome sequencing in clinical practice and research studies. By analyzing genomic variants of humans, scientists can gain better understanding of the risk factors of co…

Effect of Pegylated-interferon (Peg-inf) Plus Ribavirin (Rbv) Therapy on Haematological Profile of Different Age Groups Infected by Hepatitis C Virus in Pakistan Open

Aziz Ur Rehman, Sajjad Ali Shah, Rehana Masood, Aisha Siddique, Amir Atlas , et al. · 2025

Background and Aims: With an estimated 11.55% adult population carrying HCV, hepatitis is a serious public health concern in Pakistan. With almost one in every 20 Pakistanis already infected, the nation ranks second internationally in term…

Iron Pill–Induced Gastritis in a Pediatric Patient Taking Ferrous Sulfate Tablets Open

Charles B. Chen, Shreeya S Chugh, Deepthi Rao · 2024

Iron supplementation is frequently used in the treatment of iron deficiency anemia in the pediatric population. We describe a case of an 11-year old male who developed adverse side effects following treatment with oral ferrous sulfate tabl…

A Scalable Tool For Analyzing Genomic Variants Of Humans Using Knowledge Graphs and Machine Learning Open

Shivika Prasanna, Ajay Kumar, Deepthi Rao, Eduardo J. Simões, Praveen Rao · 2024

The integration of knowledge graphs and graph machine learning (GML) in genomic data analysis offers several opportunities for understanding complex genetic relationships, especially at the RNA level. We present a comprehensive approach fo…

An Atypical Case of Extrapulmonary Sarcoidosis with Severe Hypercalcemia as Initial Presentation, Successfully Treated with Glucocorticoids Open

Sushmita Mittal, Karolina Pogorzelski, Christopher Huxel, Chokkalingam Siva, Deepthi Rao · 2024

Background: Sarcoidosis is a multisystemic disease that is histologically characterized by non-caseating granulomas in one or more organs. Although hypercalcemia is commonly seen in sarcoidosis, clinically significant hypercalcemia as the …

A Multi-Modal CNN-based Approach for COVID-19 Diagnosis using ECG, X-Ray, and CT Open

Kumar Keshamoni, L. Koteswara Rao, Deepthi Rao · 2024

Controlling the spread of Coronavirus Disease 2019 (COVID-19) and reducing its impact on public health need prompt identification and treatment. To improve diagnostic accuracy, this study attempts to create and assess a Multi-Modality COVI…

Scalable Knowledge Graph Construction and Inference on Human Genome Variants Open

Shivika Prasanna, Deepthi Rao, Eduardo J. Simões, Praveen Rao · 2023

Real-world knowledge can be represented as a graph consisting of entities and relationships between the entities. The need for efficient and scalable solutions arises when dealing with vast genomic data, like RNA-sequencing. Knowledge grap…

Co-Presentation of Lupus Nephritis with Autoimmune Hepatitis Open

Fizah S. Chaudhary, Amit Sureen, Muhammad Nadeem Yousaf, Deepthi Rao, Chokkalingam Siva · 2023

BACKGROUND Systemic lupus erythematosus (SLE) is a multiorgan immunologic disease which commonly results in systemic manifestations by involving joints, kidneys, skin, heart, hematologic cell lines, pulmonary and central nervous systems. T…

EUS–guided versus percutaneous liver biopsy: A prospective randomized clinical trial Open

Ahmad H. Ali, Naren S. Nallapeta, Muhammad Nadeem Yousaf, Gregory F. Petroski, Neal Sharma , et al. · 2023

Background and Objectives Prospective studies comparing EUS–guided liver biopsy (EUS-LB) to percutaneous LB (PC-LB) are scarce. We compared the efficacy and safety of EUS-LB with those of PC-LB in a prospective randomized clinical trial. M…

Tumoral Intraductal Neoplasms of the Bile Ducts Comprise Morphologically and Genetically Distinct Entities Open

Tao Wang, Gokce Askan, Kerem Özcan, Satshil Rana, Ahmet Zehir , et al. · 2023

Context.— Tumoral (grossly visible) intraductal neoplasms of the bile ducts are still being characterized. Objective.— To investigate their morphologic, immunohistochemical, and molecular features. Design.— Forty-one cases were classified …

Is the Primary Tumor Site of Ampullary Carcinoma Distinct in the Setting of Morphology Subtype? Open

Chip J. Smith, Kenneth F. Scott, Deepthi Rao · 2022

Introduction/Objective Ampullary cancer (AC) are rare and represents only 6% of the malignant periampullary tumors. Two main histologic subtypes of AC are pancreatobiliary (Pb-AC), and intestinal (In-AC). The data on the influencing role o…

An Extremely Rare Variant of Pancreatic Ductal Adenocarcinoma Masquerading as Chronic Pancreatitis Open

Chip J. Smith, Kenneth F. Scott, Timothy Parrett, Deepthi Rao · 2022

Introduction/Objective Primary Pancreatic signet-ring cell carcinoma (PPSRCC) is an extremely rare histologic variant with sparse literature. Herein, we describe a case of PPSRCC in a 75-year-old female with positive family history of panc…

A Case Series of Gastric Metastatic Growths Open

Mustafa Gandhi, Harleen Chela, Hamza Ertugrul, Alhareth Al Juboori, Karthik Gangu , et al. · 2022

Gastric cancer is one of the gastrointestinal malignancies that can be quite devastating with high morbidity and mortality. Unfortunately, it is a malignancy that is encountered all across the world and is often brought into suspicion base…

Kratom (Mitragyna speciosa)-Induced Hepatitis Open

Devin Allison, Muhammed Mubarak, Neal Sharma, Deepthi Rao · 2022

Kratom is a plant with opioid-like properties known to produce stimulant and analgesic effects. Although there are numerous studies on the psychoactive components of kratom, less is known about the toxicity. Specifically, few reports descr…

Evolving robotic process automation (RPA) & artificial intelligence (AI) in response to Covid-19 and its future Open

Deepthi Rao, Pankaj Pathak · 2022

The recent outbreak of COVID-19 across the globe has been a challenge not just to the health & well-being of people. However, it has also led to a downturn in the economy throughout the world. The purpose of this study is to thoroughly inv…

DISSEMINATED MULTIFOCAL MUCORMYCOSIS TREATED WITH A COMBINATION ANTIFUNGAL REGIMEN Open

Sachin Patil, BLAINE WINTERTON, Phillip Paul Beck, Paragkumar Patel, Deepthi Rao , et al. · 2021

Endoscopic Ultrasound-Guided Liver Biopsy; the Pathologist’s Perspective Open

Naren S. Nallapeta, Deepthi Rao, Ahmad H. Ali, Neal Sharma, Jamal A. Ibdah , et al. · 2020

In this study, the safety and efficacy of liver biopsies performed by endoscopic ultrasound (EUS-LB) were compared with those performed via the traditional percutaneous route at our Medical Center between January 2018 and August 2019.

Hepatoblastoma With Rubinstein-Taybi Syndrome: A Rare Association Open

Juwairiya Arshi, David C. Allison, Deepthi Rao · 2020

Introduction/Objective Hepatoblastoma is a malignant neoplasm of liver, exclusively seen in pediatric population. It has been known to occur with various syndromes like Li-fraumeni, Beckwith-Wiedemann, and Simpson-Golabi- Behmel among othe…

The efficacy and safety of endoscopic ultrasound-guided liver biopsy versus percutaneous liver biopsy in patients with chronic liver disease: a retrospective single-center study Open

Ahmad H. Ali, Sarjukumar Panchal, Deepthi Rao, Yujun Gan, Alhareth Al-Juboori , et al. · 2020

Endoscopic full-thickness resection of a long intussuscepted appendix by use of a colonoscope Open

Ghassan M. Hammoud, Jacob A. Quick, Sami Samiullah, Deepthi Rao, Jamal A. Ibdah · 2018

Limited role of Chromogranin A as clinical biomarker for pancreatic neuroendocrine tumors Open

Alessandra Pulvirenti, Deepthi Rao, Caitlin A. McIntyre, Mithat Gönen, Laura H. Tang , et al. · 2018

Portal Cavernoma Cholangiopathy Open

Meredith E. Pittman, Andrea S. Kierans, Deepthi Rao, Rhonda K. Yantiss, Benjamin Samstein , et al. · 2018

This case series provides clinicopathologic characteristics of portal cavernoma cholangiopathy. Histologic changes are reminiscent of hepatoportal sclerosis and/or bile duct obstruction. Attention to portal veins can provide helpful diagno…

Diagnostic Aspects of Exocrine Pancreatic Insufficiency (EPI) in Canines Open

Ambica Gadige, Deepthi Rao, Anil Kumar Banothu · 2018

Transgelin: a potentially useful diagnostic marker differentially expressed in triple-negative and non–triple-negative breast cancers Open

Deepthi Rao, Bruce F. Kimler, Warren B. Nothnick, Marilyn Davis, Fang Fan , et al. · 2015

High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA Open

Benjamin Powers, Diane L. Persons, Deepthi Rao, Janet Woodroof, Tara L. Lin · 2015

Acute promyelocytic leukemia (APL) is classically characterized by chromosomal translocation (15;17), resulting in the PML-RARA fusion protein leading to disease. Here, we present a case of a 50-year-old man who presented with signs and sy…

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