Norbert Müller
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View article: Navigating infection by pathogenic spirochetes: The host‐bacteria interface at the atomic level
Navigating infection by pathogenic spirochetes: The host‐bacteria interface at the atomic level Open
Pathogenic spirochetes bind and interact with various host structures and molecules throughout the course of infection. By utilizing their outer surface molecules, spirochetes can effectively modulate their dissemination, interact with imm…
View article: STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening
STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening Open
View article: RiboScreenTM Technology Delivers a Ribosomal Target and a Small-Molecule Ligand for Ribosome Editing to Boost the Production Levels of Tropoelastin, the Monomeric Unit of Elastin
RiboScreenTM Technology Delivers a Ribosomal Target and a Small-Molecule Ligand for Ribosome Editing to Boost the Production Levels of Tropoelastin, the Monomeric Unit of Elastin Open
Elastin, a key structural protein essential for the elasticity of the skin and elastogenic tissues, degrades with age. Replenishing elastin holds promise for anti-aging cosmetics and the supplementation of elastic activities of the cardiov…
View article: Two Sides of Theory of Mind: Mental State Attribution to Moving Shapes in Paranoid Schizophrenia Is Independent of the Severity of Positive Symptoms
Two Sides of Theory of Mind: Mental State Attribution to Moving Shapes in Paranoid Schizophrenia Is Independent of the Severity of Positive Symptoms Open
Background: Theory of Mind (ToM) impairment has repeatedly been found in paranoid schizophrenia. The current study aims at investigating whether this is related to a deficit in ToM (undermentalizing) or an increased ToM ability to hyperatt…
View article: Estimation of Radiation Damping Rates Using 133Cs, 7Li and 31P Solution NMR Spectroscopy and a Theoretical NMR RASER Model
Estimation of Radiation Damping Rates Using 133Cs, 7Li and 31P Solution NMR Spectroscopy and a Theoretical NMR RASER Model Open
Radio amplification using stimulated emission of radiation (RASER) effects in the NMR can increase NMR signals over time due to a feedback loop between the sample magnetization and the probe coil coupled with radiation damping (RD). Previo…
View article: The Interplay of Oxytocin and Attachment in Schizophrenic Patients: An fMRI Study
The Interplay of Oxytocin and Attachment in Schizophrenic Patients: An fMRI Study Open
Background: Attachment theory offers an important framework for understanding interpersonal interaction experiences. In the present study, we examined the neural correlates of attachment patterns and oxytocin in schizophrenic patients (SZP…
View article: Premature T cell aging in major depression: A double hit by the state of disease and cytomegalovirus infection
Premature T cell aging in major depression: A double hit by the state of disease and cytomegalovirus infection Open
View article: Wave disc engine apparatus
Wave disc engine apparatus Open
A wave disc engine apparatus is provided. A further aspect employs a constricted nozzle in a wave rotor channel. A further aspect provides a sharp bend between an inlet and an outlet in a fluid pathway of a wave rotor, with the bend being …
View article: Tryptophan metabolites predict response after cognitive behavioral therapy for depression: A single-arm trial.
Tryptophan metabolites predict response after cognitive behavioral therapy for depression: A single-arm trial. Open
Background: Cognitive behavioral therapy (CBT) is one of the most prominent standard treatments for depression. However, like with antidepressant drugs, a subgroup of patients remains unresponsive. Since an imbalance in serotonin and kynur…
View article: Editorial: Environmental risk factors and inflammation in psychiatric and neurological disease
Editorial: Environmental risk factors and inflammation in psychiatric and neurological disease Open
EDITORIAL article Front. Psychiatry, 07 December 2022Sec. Molecular Psychiatry Volume 13 - 2022 | https://doi.org/10.3389/fpsyt.2022.1080761
View article: Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study
Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study Open
ObjectiveTo investigate the association between Group-A streptococcal (GAS) infections and tic incidence among unaffected children with a family history of chronic tic disorders (CTD).MethodsIn a prospective cohort study, children with no …
View article: Spin noise gradient echoes
Spin noise gradient echoes Open
Nuclear spin noise spectroscopy in the absence of radio frequency pulses was studied under the influence of pulsed field gradients (PFGs) on pure and mixed liquids. Under conditions where the radiation-damping-induced line broadening is sm…
View article: Mycoplasma pneumoniae IgG positivity is associated with tic severity in chronic tic disorders
Mycoplasma pneumoniae IgG positivity is associated with tic severity in chronic tic disorders Open
View article: Efficacy of Sertraline Plus Placebo or Add-On Celecoxib in Major Depressive Disorder: Macrophage Migration Inhibitory Factor as a Promising Biomarker for Remission After Sertraline—Results From a Randomized Controlled Clinical Trial
Efficacy of Sertraline Plus Placebo or Add-On Celecoxib in Major Depressive Disorder: Macrophage Migration Inhibitory Factor as a Promising Biomarker for Remission After Sertraline—Results From a Randomized Controlled Clinical Trial Open
Introduction: Previous research delivers strong indications that inflammatory activation leads to treatment resistance in a subgroup of patients with Major Depressive Disorder (MDD). Thus, tailored interventions are needed. The present stu…
View article: Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders
Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders Open
Objective Disturbances in the kynurenine pathway have been implicated in the pathophysiology of psychotic and mood disorders, as well as several other psychiatric illnesses. It remains uncertain however to what extent metabolite levels det…
View article: Resonance assignment of coiled-coil 3 (CC3) domain of human STIM1
Resonance assignment of coiled-coil 3 (CC3) domain of human STIM1 Open
The protein stromal interaction molecule 1 (STIM1) plays a pivotal role in mediating store-operated calcium entry (SOCE) into cells, which is essential for adaptive immunity. It acts as a calcium sensor in the endoplasmic reticulum (ER) an…
View article: Resonance assignment and secondary structure of DbpA protein from the European species, Borrelia afzelii
Resonance assignment and secondary structure of DbpA protein from the European species, Borrelia afzelii Open
Decorin binding proteins (Dbps) mediate attachment of spirochetes in host organisms during the early stages of Lyme disease infection. Previously, different binding mechanisms of Dbps to glycosaminoglycans have been elucidated for the path…
View article: Spin-Noise Gradient Echoes
Spin-Noise Gradient Echoes Open
Nuclear spin-noise spectroscopy in absence of radio frequency pulses was studied under the influence of pulsed field gradients (PFGs) on pure and mixed liquids. Under conditions, where the radiation-damping induced line broadening is small…
View article: Supplementary material to "Spin-Noise Gradient Echoes"
Supplementary material to "Spin-Noise Gradient Echoes" Open
Simulations of spin-noise gradient echoTo assess the effect of SNGE, we perform simulations using Mathematica (Wolfram Research Inc., 2012) based on the Bloch equations (Bloch, 1946), and neglecting any effect of radiation damping.This las…
View article: Monocyte mitochondrial dysfunction, inflammaging, and inflammatory pyroptosis in major depression
Monocyte mitochondrial dysfunction, inflammaging, and inflammatory pyroptosis in major depression Open
View article: Tic disorders in children and adolescents: does the clinical presentation differ in males and females? A report by the EMTICS group
Tic disorders in children and adolescents: does the clinical presentation differ in males and females? A report by the EMTICS group Open
View article: Association of Group A <i>Streptococcus</i> Exposure and Exacerbations of Chronic Tic Disorders
Association of Group A <i>Streptococcus</i> Exposure and Exacerbations of Chronic Tic Disorders Open
This study does not support GAS exposures as contributing factors for tic exacerbations in children with CTD. Specific workup or active management of GAS infections is unlikely to help modify the course of tics in CTD and is therefore not …
View article: Additional file 7 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 7 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 7: Table S5. Comparative genomic assessment of mitochondrial genes in Naegleria spp.
View article: Additional file 1 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 1 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 1: Table S1. % identity of SSU rRNA genes. Sheet 1: Naegleria species. Sheet 2: Selected tetrapod organisms.
View article: Additional file 10 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 10 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 10: Table S8. Comparative genomics analysis of Ras superfamily GTPases in Naegleria spp.
View article: Additional file 5 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 5 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 5: Table S3. Transcription factors in Naegleria spp.
View article: Additional file 9 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 9 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 9: Table S7. Results of homology searching for membrane trafficking components in the predicted proteomes and genomes of N. fowleri V212, 39863, and 986.
View article: Additional file 12 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 12 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 12: Table S10. Differentially expressed genes following mouse-passage of N. fowleri LEE. Grey shading indicates genes found in N. fowleri alone or N. fowleri.
View article: Additional file 18 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 18 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 18: Table S16. Predicted adhesion G protein-coupled receptors in Naegleria spp.
View article: Additional file 15 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
Additional file 15 of Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri Open
Additional file 15: Table S13. Comparative genomic analysis of genes involved in autophagy in N. fowleri.