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View article: Giving a voice to early career midwives who desire to work in midwifery continuity of care: a co-designed approach
Giving a voice to early career midwives who desire to work in midwifery continuity of care: a co-designed approach Open
Early career midwives identified aspects of their experiences which helped or hindered their goal to work in midwifery continuity models. A co-designed survey was developed to gain further insight into this topic.
View article: Dissecting aortitis in a goat associated with Pasteurella multocida and Staphylococcus spp infection
Dissecting aortitis in a goat associated with Pasteurella multocida and Staphylococcus spp infection Open
Reports of primary cardiovascular disease in goats are rare and most commonly include ventricular septal defect, valvular endocarditis, traumatic pericarditis, ionophore poisoning and nutritional cardiomyopathies. We now report the patholo…
View article: Characterization of clinical presentation, histological features, ultrasonographic findings, and survival in 29 dogs with granulomatous hepatitis
Characterization of clinical presentation, histological features, ultrasonographic findings, and survival in 29 dogs with granulomatous hepatitis Open
Background Granulomatous hepatitis (GH) is a form of chronic hepatitis (CH) in dogs for which limited information is published. Hypothesis Describe the clinical presentation, clinical pathology, ultrasound, and hepatic histopathology findi…
View article: Quality Improvement Project to Improve the Implementation of Mental Health Act Code of Practice Guiding Principles and Patient Knowledge About MHA in In-Patient Psychiatric Unit
Quality Improvement Project to Improve the Implementation of Mental Health Act Code of Practice Guiding Principles and Patient Knowledge About MHA in In-Patient Psychiatric Unit Open
Aims To improve the efficiency of MHA documentation, patient education on MHA and implementation of guidelines of Code of Practice in in-patient unit. We also aimed to involve patients at some stages of the QI project to ensure they remain…
View article: Supplementary Table 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 52K, Networks associated to differentially expressed genes by Ingenuity Pathway Analysis. Genes in capital letters represent differentially expressed genes found within the network. A. Top networks associated with E2 treatment o…
View article: Supplementary Table 5 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 5 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 49K, Biological functions and canonical pathways associated with TAM treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physiological Sys…
View article: Supplementary Figure 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Figure 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 915K, Significant molecular networks affected by E2 treatment (P=10-50). P-values represent the probability of these interactions occurring by chance.
View article: Supplementary Figure 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Figure 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 529K, Significant molecular networks affected by the common genes between E2 and TAM treatments (P=10-45). P-values represent the probability of these interactions occurring by chance.
View article: Supplementary Figure 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Figure 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 419K, Significant molecular networks affected by Tamoxifen treatment (P=10-45). P-values represent the probability of these interactions occurring by chance.
View article: Supplementary Table 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 45K, Individual histological parameters in the corpus and antrum at 16 and 28 weeks of H. pylori infection. A) Corpus pathology at 16 WPI. B) Corpus pathology at 28 WPI. C) Antrum pathology at 16 WPI. D) Antrum pathology at 28 W…
View article: Data from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Data from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
Helicobacter pylori infection promotes male predominant gastric adenocarcinoma in humans. Estrogens reduce gastric cancer risk and previous studies showed that prophylactic 17β-estradiol (E2) in INS-GAS mice decreases H. pylori–induced car…
View article: Supplementary Table 5 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 5 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 49K, Biological functions and canonical pathways associated with TAM treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physiological Sys…
View article: Supplementary Table 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 45K, Individual histological parameters in the corpus and antrum at 16 and 28 weeks of H. pylori infection. A) Corpus pathology at 16 WPI. B) Corpus pathology at 28 WPI. C) Antrum pathology at 16 WPI. D) Antrum pathology at 28 W…
View article: Supplementary Figure 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Figure 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 529K, Significant molecular networks affected by the common genes between E2 and TAM treatments (P=10-45). P-values represent the probability of these interactions occurring by chance.
View article: Supplementary Table 4 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 4 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 53K, Biological functions and canonical pathways associated with E2 treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physiological Syst…
View article: Data from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Data from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
Helicobacter pylori infection promotes male predominant gastric adenocarcinoma in humans. Estrogens reduce gastric cancer risk and previous studies showed that prophylactic 17β-estradiol (E2) in INS-GAS mice decreases H. pylori–induced car…
View article: Supplementary Table 6 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 6 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 48K, Biological functions and canonical pathways associated with both E2 and TAM treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physi…
View article: Supplementary Table 4 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 4 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 53K, Biological functions and canonical pathways associated with E2 treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physiological Syst…
View article: Supplementary Figure 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Figure 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 419K, Significant molecular networks affected by Tamoxifen treatment (P=10-45). P-values represent the probability of these interactions occurring by chance.
View article: Supplementary Figure 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Figure 1 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 915K, Significant molecular networks affected by E2 treatment (P=10-50). P-values represent the probability of these interactions occurring by chance.
View article: Supplementary Table 6 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 6 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 48K, Biological functions and canonical pathways associated with both E2 and TAM treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physi…
View article: Supplementary Table 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 110K, Genes differentially expressed by treatment. A. 169 downregulated and 194 upregulated genes in infected E2 male mice compared to infected untreated male mice. B. 69 downregulated and 75 upregulated genes in infected TAM ma…
View article: Supplementary Table 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 2 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 110K, Genes differentially expressed by treatment. A. 169 downregulated and 194 upregulated genes in infected E2 male mice compared to infected untreated male mice. B. 69 downregulated and 75 upregulated genes in infected TAM ma…
View article: Supplementary Table 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice
Supplementary Table 3 from 17β-Estradiol and Tamoxifen Prevent Gastric Cancer by Modulating Leukocyte Recruitment and Oncogenic Pathways in <i>Helicobacter Pylori</i>–Infected INS-GAS Male Mice Open
PDF file - 52K, Networks associated to differentially expressed genes by Ingenuity Pathway Analysis. Genes in capital letters represent differentially expressed genes found within the network. A. Top networks associated with E2 treatment o…
View article: Polyorchidism in a cat
Polyorchidism in a cat Open
A 9-mo-old, male domestic shorthair cat was presented for castration because of mounting behavior observed by the owner. On physical examination, the cat was bilaterally cryptorchid, but had penile spines. Abdominal exploration through a m…
View article: A Novel Digital Algorithm for Identifying Liver Steatosis Using Smartphone-Captured Images
A Novel Digital Algorithm for Identifying Liver Steatosis Using Smartphone-Captured Images Open
Background. Access to lifesaving liver transplantation is limited by a severe organ shortage. One factor contributing to the shortage is the high rate of discard in livers with histologic steatosis. Livers with <30% macrosteatosis are gene…
View article: Outcome and Prognostic Factors in Cats Undergoing Resection of Intestinal Adenocarcinomas: 58 Cases (2008–2020)
Outcome and Prognostic Factors in Cats Undergoing Resection of Intestinal Adenocarcinomas: 58 Cases (2008–2020) Open
The purpose of this multi-institutional retrospective study was to expand the available data pertaining to pre-operative clinical findings, progression-free and overall survival times, and potential prognostic factors for cats undergoing s…
View article: Activation of autophagy during normothermic machine perfusion of discarded livers is associated with improved hepatocellular function
Activation of autophagy during normothermic machine perfusion of discarded livers is associated with improved hepatocellular function Open
We demonstrate that ischemia-reperfusion injury occurs in all livers during NMP, though there are notable differences in gene expression between functional and nonfunctional livers. We further demonstrate that activation of the liver’s rep…
View article: Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model
Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model Open
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Epigenetic dysregulation is hypothesized to play a role in the observed association between inflammatory bowel disease (IBD) and colon tumor development. In the present work, DNA me…