N. J. P. Subhashini
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View article: Synthesis and Characterization of Novel Indole Containing 1,2,3-Triazole Linked 1,3,4-Thiadiazole Hybrids: Evaluation of Anticancer Activity and Molecular Docking Studies
Synthesis and Characterization of Novel Indole Containing 1,2,3-Triazole Linked 1,3,4-Thiadiazole Hybrids: Evaluation of Anticancer Activity and Molecular Docking Studies Open
Novel scaffolds containing indole, 1,2,3-triazole linked thiadiazole derivatives (9a-l) were synthesized and confirmed with analytical techniques like 1H NMR, 13C NMR and LC-MS. All the compounds were further screened for their anticancer …
View article: Heart Check: Predictive Analytics for Early Heart Disease Detection using Machine Learning
Heart Check: Predictive Analytics for Early Heart Disease Detection using Machine Learning Open
Heart diseases or cardiovascular diseases refer to a variety of conditions that affect your heart health like the blood vessel problem, irregular heartbeat rhythms as well as congenital heart defects. Being a mentioned top cause of death w…
View article: Design, Synthesis, Molecular Docking Studies and Anticancer activity of 5-sustituted-3-((2-(4-nitrophenyl) Thiazol-4-yl) Imino)-1-(substituted-1-ylmethyl) Indolin-2-one Scaffolds
Design, Synthesis, Molecular Docking Studies and Anticancer activity of 5-sustituted-3-((2-(4-nitrophenyl) Thiazol-4-yl) Imino)-1-(substituted-1-ylmethyl) Indolin-2-one Scaffolds Open
A new series of 5-sustituted-3-((2-(4-nitrophenyl) Thiazol-4-yl) Imino)-1-(substituted-1-ylmethyl) Indolin-2-one derivatives (3a-3l) are synthesized by conventional method. All synthesized compounds were characterized via IR, 1H-NMR, 13C-N…
View article: TELMISARTAN AND AZELNIDIPINE QUANTIFICATION EMPLOYING HPLC STRATAGEM; STABILITY INVESTIGATION ON TELMISARTAN AND AZELNIDIPINE
TELMISARTAN AND AZELNIDIPINE QUANTIFICATION EMPLOYING HPLC STRATAGEM; STABILITY INVESTIGATION ON TELMISARTAN AND AZELNIDIPINE Open
Objective: The focus of our research was to create a fairly sensitive HPLC stratagem for determining telmisartan (TLM) and azelnidipine (AEL) in bulk and tablet types. Methods: Analysis of TLM and AEL was performed on a “C18 Kromasil stati…
View article: Synthesis, Molecular Docking Studies, Antimicrobial, Anticancer andAntioxidant Activity of Some Novel Mannich Bases of Isatin Scaffold
Synthesis, Molecular Docking Studies, Antimicrobial, Anticancer andAntioxidant Activity of Some Novel Mannich Bases of Isatin Scaffold Open
A series of novel Mannich bases of isatin derivatives (VIIIa-VIIIt) was synthesized and evaluated as potential antimicrobial, antioxidant, anticancer activities and molecular docking studies. Structure of all the isatin derivatives was eva…
View article: 1-(3-ACETYL PHENYL)-4-(4-ARYLIDENE)-2-PHENYL-1HIMIDAZOL-5(4H)-ONES: SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, ANTIMICROBIAL AND MOLECULAR DOCKING STUDIES
1-(3-ACETYL PHENYL)-4-(4-ARYLIDENE)-2-PHENYL-1HIMIDAZOL-5(4H)-ONES: SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, ANTIMICROBIAL AND MOLECULAR DOCKING STUDIES Open
Imidazole rings are privileged moieties in heterocyclic chemistry since they permit functional group and structural modifications to synthesize abundant substituted heterocycles.Thus, the pursuit of exploring many more alterations on imida…
View article: Isolation, Molecular Characterization and Antimicrobial Resistance Patterns of Four Different Vibrio Species Isolated from Fresh Water Fishes
Isolation, Molecular Characterization and Antimicrobial Resistance Patterns of Four Different Vibrio Species Isolated from Fresh Water Fishes Open
Vibrio species are the major food borne pathogens commonly associated with aquatic food poisonings and lead to food-borne outbreaks. In this present study, out of 105 fresh water fish (Catlacatla) samples collected, 87 (82.85%) were found …