Toshiyuki Yoneda
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View article: Editorial comment
Editorial comment Open
View article: How to take initiative of and how to plan for urban park renovation
How to take initiative of and how to plan for urban park renovation Open
View article: Development of a PCR method for rapid detection of Leptospira from one microliter of whole blood
Development of a PCR method for rapid detection of Leptospira from one microliter of whole blood Open
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira. Its diagnosis is usually difficult, often resulting in delayed antimicrobial therapy and worse outcomes. Nucleic acid amplification tests of blood provide reliable Lept…
View article: JSBMR and JBMM mourn the death of Dr. Fujio Suzuki
JSBMR and JBMM mourn the death of Dr. Fujio Suzuki Open
View article: The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons
The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons Open
Cancers showing excessive innervation of sensory neurons (SN) in their microenvironments are associated with poor outcomes due to promoted growth, increased tumor recurrence, metastasis, and cancer pain, suggesting SNs play a regulatory ro…
View article: Cancer and bone: friendly and hostile relationship
Cancer and bone: friendly and hostile relationship Open
View article: Supplementary Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells
Supplementary Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells Open
Supplementary Figures S1-S7; Supplementary Table S1.
View article: Supplementary Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells
Supplementary Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells Open
Supplementary Figures S1-S7; Supplementary Table S1.
View article: Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells
Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells Open
Accumulating evidence indicates that the acidic microenvironments critically influence malignant behaviors of cancer including invasiveness, metastasis, and chemoresistance. Because the vacuolar-type H+-ATPase (V-ATPase) has bee…
View article: Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells
Data from The <i>a</i>3 Isoform Vacuolar Type H<sup>+</sup>-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells Open
Accumulating evidence indicates that the acidic microenvironments critically influence malignant behaviors of cancer including invasiveness, metastasis, and chemoresistance. Because the vacuolar-type H+-ATPase (V-ATPase) has bee…
View article: Supplementary figure 3 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure 3 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure 3. Osteocytes regulate cell proliferation and Notch receptor expression in MM cells.
View article: Data from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Data from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
In multiple myeloma, an overabundance of monoclonal plasma cells in the bone marrow induces localized osteolytic lesions that rarely heal due to increased bone resorption and suppressed bone formation. Matrix-embedded osteocytes comprise m…
View article: Supplementary figure 2 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure 2 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure 2. MM cells increase Rankl mRNA levels in osteocytes.
View article: Supplementary figure legends from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure legends from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure legends
View article: Supplementary figure 2 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure 2 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure 2. MM cells increase Rankl mRNA levels in osteocytes.
View article: Data from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Data from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Multiple myeloma patients experience severe bone pain (MMBP) that is undertreated and poorly understood. In this study, we studied MMBP in an intratibial mouse xenograft model that employs JJN3 human multiple myeloma cells. In this model, …
View article: Supplementary methods from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary methods from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary methods
View article: Supplemental Figure Legend from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Supplemental Figure Legend from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Legend for Supplementary Figures S1-S2.
View article: Data from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Data from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
In multiple myeloma, an overabundance of monoclonal plasma cells in the bone marrow induces localized osteolytic lesions that rarely heal due to increased bone resorption and suppressed bone formation. Matrix-embedded osteocytes comprise m…
View article: Supplementary Figure S1 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Supplementary Figure S1 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Characterization of 5TGM1 mouse MM cells in vivo and in vitro.
View article: Supplementary figure legends from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure legends from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure legends
View article: Supplementary figure 3 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure 3 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure 3. Osteocytes regulate cell proliferation and Notch receptor expression in MM cells.
View article: Supplementary Figure S1 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Supplementary Figure S1 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Characterization of 5TGM1 mouse MM cells in vivo and in vitro.
View article: Data from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Data from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Multiple myeloma patients experience severe bone pain (MMBP) that is undertreated and poorly understood. In this study, we studied MMBP in an intratibial mouse xenograft model that employs JJN3 human multiple myeloma cells. In this model, …
View article: Supplementary figure 1 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure 1 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure 1. MM cells induce apoptosis and activate Notch signaling in osteocytes.
View article: Supplementary Figure S2 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Supplementary Figure S2 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Contribution of TRPV1 to sprouting and activation of SN and MMBP in JJN3-injected mice.
View article: Supplementary methods from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary methods from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary methods
View article: Supplementary figure 1 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Supplementary figure 1 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma Open
Supplementary figure 1. MM cells induce apoptosis and activate Notch signaling in osteocytes.
View article: Supplementary Figure S2 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Supplementary Figure S2 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Contribution of TRPV1 to sprouting and activation of SN and MMBP in JJN3-injected mice.
View article: Supplemental Figure Legend from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Supplemental Figure Legend from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 Open
Legend for Supplementary Figures S1-S2.